Abstract
Chronic hypertrophic and dilative heart disease is one of the most common cardiac diseases in man (1). From the functional point of view, ventricular hypertrophy provides a basic mechanism that permits the heart to maintain normal cardiac pump function despite abnormal pressure, stress, or volume load (5–8, 13). However, progression of cardiac hypertrophy is a significant precursor of cardiac dilatation and failure and of coronary insufficiency. Therefore, the question has been raised whether specific regression of hypertrophy (14, 15) might be appropriate to prevent both the myocardial and coronary consequences of cardiac hypertrophy.
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References
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Strauer, B.E., Motz, W. (1983). Functional and Metabolic Consequences of Chronic Alterations in Preload and Afterload in the Hypertrophied and Dilated Heart. In: Just, H., Bussmann, WD. (eds) Vasodilators in Chronic Heart Failure. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68605-4_2
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DOI: https://doi.org/10.1007/978-3-642-68605-4_2
Publisher Name: Springer, Berlin, Heidelberg
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