Abstract
Investigation of the structure and function of antigen-specific molecules synthesized by T cells is a major aspect of current immunological research, since such molecules have an important role in immune regulation. A partial understanding of the structure of T cell factors and receptors has resulted from analysis of antigen-binding materials derived from relatively crude T cell sources, such as activated T cells (e.g. Feldmann and Basten, 1972; Binz and Wigzell, 1975), and this has been confirmed using more homogeneous T cell sources (T cell hybrids, TCGF-dependent lines, virus tranformed lines etc). This understanding has been enhanced by the use of various antisera which recognise T cell factors and receptors.
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Culbert, E.J., Kontiainen, S., Douglas, L.M., Feldmann, M. (1982). Definition of Function-Related Isotypic Markers on T Cells. In: Boehmer, H.V., Haas, W., Köhler, G., Melchers, F., Zeuthen, J. (eds) T Cell Hybridomas. Current Topics in Microbiology and Immunology, vol 100. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68586-6_3
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DOI: https://doi.org/10.1007/978-3-642-68586-6_3
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