Ioglunide: A New Contrast Medium for Myelography and Cisternography (Animal Experiments and Preliminary Clinical Experience)

  • R. E. Gonsette
  • L. Liesenborgh
Conference paper

Abstract

Since 1972, metrizamide (Amipaque) has been extensively used for the opacification of perimedullary and pericerebral spaces, and there is a general agreement that the neurotoxicity of this new contrast medium (CM) is definitely lower than that of previous ionic iodinated compounds.

Keywords

Sugar Toxicity Iodine Neurotoxicity Iopamidol 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bertoni JM, Schwartzman RJ, Van Horn G, Partin J (1981) Asterixis and encephalopathy following Metrizamide myelography: investigations into possible mechanisms and review of literature. Ann Neurol 9:366–370PubMedCrossRefGoogle Scholar
  2. 2.
    Gonsette RE, Brucher JM (1980) Neurotoxicity of novel water-soluble contrast media for intrathecal application. Invest Radiol 15:254–259CrossRefGoogle Scholar
  3. 3.
    Gonsette RE (to be published) Immediate and delayed neurotoxicity of newly synthesized contrast media demonstrated by EEG sequential analysis.Google Scholar
  4. 4.
    Haughton VM, Ho KC (1980) The risk of arachnoiditis from experimental nonionic contrast media. Radiology 136:395–397PubMedGoogle Scholar
  5. 5.
    Hilal SK, Dauth GW, Hess KH, Gilman S (1978) Development and evaluation of a new water-soluble iodinated myelographic contrast medium with markedly reduced convulsive effects. Radiol 126:417–422Google Scholar
  6. 6.
    Picard L, Vespignani H, Vieux-Rochat P, et al. (1979) Serious neurological complications of Metrizamide myelography. Report of 8 cases. J Neuroradiol 6:3–14PubMedGoogle Scholar
  7. 7.
    Richert S, Sartor K, Holl B (1979) Subclinical organic psychosyndromes on intrathecal injection of Metrizamide for lumbar myelography. Neuroradiology 18:177–184PubMedCrossRefGoogle Scholar
  8. 8.
    Ropper AH, Chiappa KH, Young RR (1979) The effect of Metrizamide on the electroencephalogram: a prospective study in 61 patients. Ann Neurol 6:222–226PubMedCrossRefGoogle Scholar
  9. 9.
    Schmidt RC (1980) Mental disorders after myelography with Metrizamide and other water-soluble contrast media. Neuroradiology 19:153–157PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • R. E. Gonsette
  • L. Liesenborgh

There are no affiliations available

Personalised recommendations