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The Pyrogenic Responses of Non-mammalian Vertebrates

  • Chapter
Pyretics and Antipyretics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 60))

Abstract

Vertebrate animals can be classified on the basis of their thermoregulatory mechanisms into endotherms and ectotherms. Endotherms produce a significant quantity of internal heat through relatively high and controllable rates of aerobic metabolism, while at the same time having a relatively low but variable thermal conductance, so that their major source of body heat is internal (Reynolds 1979). The only non-mammalian vertebrate class which is primarily endothermic is the class Aves, the birds. Some fishes (tunas and lamnid sharks), and some large varanid lizards and brooding pythons among the reptiles also show a limited degree of endothermy; but by and large, lower vertebrates (Reptilia, Amphibia, Osteichthyes, Chondrichthyes, Agnatha) are ectothermic (Reynolds 1979). Ectotherms have relatively low rates of metabolic heat production and relatively high thermal conductance (i.e. poor thermal insulation), so that most metabolic heat is rapidly lost to the environment. The major source of body heat is external; i.e. the body temperature differs little from the temperature of the environment.

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References

  • Anderson JM (1971) Assessment of the effects of pollutants on physiology and behavior.II. Sublethal effects and changes in ecosystems. Proc R Soc Lond [Biol] 77:307–320

    Google Scholar 

  • Adair ER (1974) Hypothalamic control of thermoregulatory behavior. In: Lederis K, Cooper KE (eds) Recent studies of hypothalamic function. Karger, Basel pp 341–358

    Google Scholar 

  • Bartholomew GA, Tucker VA (1964) Size, body temperature, thermal conductance, oxygen consumption and heart rate in Australian varanid lizards. Physiol Zool 37:341–354

    Google Scholar 

  • Bernheim HA, Kluger MJ (1976a) Fever and antipyresis in the lizard Dipsosaurus dor sails. Am J Physiol 231:198–203

    PubMed  CAS  Google Scholar 

  • Bernheim HA, Kluger MJ (1976b) Fever: effect of drug-induced antipyresis on survival. Science 193:237–239

    PubMed  CAS  Google Scholar 

  • Bernheim HA, Kluger MJ (1977) Endogenous pyrogen-like substance produced by reptiles. J Physiol (Lond) 267:659–666

    CAS  Google Scholar 

  • Bernheim HA, Bodel PT, Askenase PW, Atkins E (1978) Effects of fever on host defense mechanisms after infection in the lizard Dipsosaurus dorsalis. Br J Exp Pathol 59:76–84

    PubMed  CAS  Google Scholar 

  • Bishai I, Coceani F (1976) Presence of 15-hydroxy prostaglandin dehydrogenase, prostaglandin-Δ13-reductase and prostaglandin E-9-keto(α)-reductase in the frog spinal cord. J. Neurochem 26:1167–1174

    PubMed  CAS  Google Scholar 

  • Bligh J (1973) Temperature regulation in mammals and other vertebrates. North-Holland, Amsterdam

    Google Scholar 

  • Bligh J, Milton AS (1972) The thermoregulatory effects of prostaglandin E1 when infused into a lateral cerebral ventricle of the Welsh mountain sheep at different ambient temperatures. J Physiol (Lond) 229:30–31P

    Google Scholar 

  • Bligh J, Cottle WH, Maskrey M (1971) Influence of ambient temperature on the thermoregulatory responses to 5-hydroxytryptamine, noradrenaline and acetylcholine injected into the lateral cerebral ventricles of sheep, goats and rabbits. J Physiol (Lond) 212:377–392

    CAS  Google Scholar 

  • Bligh J, Louw G, Young BA (1976) Effect of cerebroventricular administration of noradrenaline and carbachol on behavioural and autonomic thermoregulation in the monitor lizard Varanus albigularis albigularis. J Therm Biol 1:241–243

    CAS  Google Scholar 

  • Brattstrom BH (1979) Amphibian temperature regulation studies in the field and laboratory. Am Zool 19:345–356

    CAS  Google Scholar 

  • Brown S, Fedoruk K, Eales JG (1978) Physical injury due to injection or blood removal causes transitory elevations of plasma thyroxine in rainbow trout,Salmo gairdneri. Can J Zool 56:1998–2003

    CAS  Google Scholar 

  • Bustard HR (1967) Activity cycle and thermoregulation in the Australian gecko Gehyra variegata. Copeia 1967:753–758

    Google Scholar 

  • Casterlin ME, Reynolds WW (1977a) Behavioral fever in anuran amphibian larvae. Life Sei 20:593–596

    CAS  Google Scholar 

  • Casterlin ME, Reynolds WW (1978a) Behavioral thermoregulation in Rana pipiens tadpoles. J Therm Biol 3:143–145

    Google Scholar 

  • Casterlin ME, Reynolds WW (1978b) Prostaglandin E1 fever in the crayfish Cambarus bartoni. Pharmacol Biochem Behav 9:593–595

    PubMed  CAS  Google Scholar 

  • Casterlin ME, Reynolds WW (1979) Shark thermoregulation. Comp Biochem Physiol [A] 64:451–453

    Google Scholar 

  • Casterlin ME, Reynolds WW, Covert JB (1978) Prostaglandin E1-and bacterial pyrogen-induced fever in aquatic ectotherms. Fed Proc 37:427

    Google Scholar 

  • Clark WG, Lipton JM (1974) Complementary lowering of the behavioural and physiological thermoregulatory set-points by tetrodotoxin and saxitoxin in the cat. J Physiol (Lond) 238:181–191

    CAS  Google Scholar 

  • Coceani F (1974) Prostaglandins and the central nervous system. Arch Intern Med 133:119–129

    PubMed  CAS  Google Scholar 

  • Coceani F (1976) Prostaglandin system in developing and mature central nervous tissue. In: Brazier MAB, Coceani E (eds) Brain dysfunction in infantile febrile convulsion. Raven, New York, pp 55–67

    Google Scholar 

  • Covert JB, Reynolds WW (1977) Survival value of fever in fish. Nature 267:43–45

    PubMed  CAS  Google Scholar 

  • Cranston WI, Duff GW, Hellon RF, Mitchell D, Townsend Y (1976) Evidence that brain prostaglandin synthesis is not essential in fever. J Physiol (Lond) 259:239–249

    CAS  Google Scholar 

  • Crawshaw LI, Hammel HT (1973) Behavioral temperature regulation in the California horn shark, Heterodontus francisci. Brain Behav Evol 7:447–452

    PubMed  CAS  Google Scholar 

  • Crawshaw LI, Hammel HT (1974) Behavioral regulation of internal temperature in the brown bullhead, Ictalurus nebulosus. Comp Biochem Physiol [A] 47:51–60

    CAS  Google Scholar 

  • Crawshaw LI, Stitt JT (1975) Behavioural and autonomic induction of prostaglandin Et fever in squirrel monkeys. J Physiol (Lond) 244:197–206

    CAS  Google Scholar 

  • D’Alecy LG, Kluger MJ (1975) Avian febrile response. J Physiol (Lond) 253:223–232

    Google Scholar 

  • Dean JM (1976) Temperatures of tissues in freshwater fishes. Trans Am Fish Soc 105:709–711

    Google Scholar 

  • Dizon AE, Brill RW (1979) Thermoregulation in tunas. Am Zool 19:249–265

    Google Scholar 

  • Domanik AM, Zar HJ (1978) The effect of malathion on the temperature selection response of the common shiner, Notropis cornutus. Bull Environ Contam Toxicol 7:193–206

    CAS  Google Scholar 

  • Elattar TMA (1978) Prostaglandins: physiology, biochemistry, pharmacology and clinical applications. J Oral Pathol 7:239–282

    PubMed  CAS  Google Scholar 

  • Engbretson GA, Hutchison VH (1976) Parietalectomy and thermal selection in the lizard Sceloporus magister. J Exp Zool 198:29–38

    PubMed  CAS  Google Scholar 

  • Feldberg W (1970) Monoamines of the hypothalamus as mediators of temperature regulation. In: The hypothalamus. Academic Press, New York

    Google Scholar 

  • Fryer JN, Ogilvie DM (1974) Temperature selection response of Atlantic salmon, Salmo salar, and rainbow trout, Salmo gairdneri, after exposure to pentobarbitol. Comp Gen Pharmacol 5:111–116

    Google Scholar 

  • Fryer JN, Ogilvie DM (1978) Alteration of thermoregulatory behavior in fish by 5-hydroxy-tryptamine. Pharmacol Biochem Behav 8:129–132

    PubMed  CAS  Google Scholar 

  • Gardner DR (1973) The effect of some DDT and methoxychlor analogs on temperature selection and lethality in brook trout fingerlings. Pestic Biochem Physiol 2:437–440

    CAS  Google Scholar 

  • Garside ET, Morrison GC (1977) Thermal preferences of mummichog, Fundulus hetero-clitus L., and banded killifish, F. diaphanus (LeSueur), (Cyprinodontidae) in relation to thermal acclimation and salinity. Can J Zool 55:1190–1194

    Google Scholar 

  • Gatten RE Jr (1974) Effect of nutritional status on the preferred body temperature of the turtles Pseudemys scripta and Terr apene ornata. Copeia 1974:912–917

    Google Scholar 

  • Green MD, Lomax P (1976) Behavioural thermoregulation and neuroamines in fish (Chromis chromis). J Therm Biol 1:237–240

    CAS  Google Scholar 

  • Green MD, Lomax P (1977) Fish (Chromis chromis) as a model for the study of thermoregulatory behavior. In: Cooper KE, Lomax P, Schönbaum E (eds) Drugs, biogenic amines and body temperature. Karger, Basel, pp 74–76

    Google Scholar 

  • Hammel HT (1968) Regulation of internal body temperature. Ann. Rev Physiol 30:641–710

    CAS  Google Scholar 

  • Hammel HT, Caldwell FT Jr, Abrams RM (1967) Regulation of body temperature in the blue-tongued lizard. Science 156:1260–1262

    PubMed  CAS  Google Scholar 

  • Hammel HT, Stromme SB, Myhre K (1969) Forebrain temperature activates behavioral thermoregulatory response in arctic sculpins. Science 165:83–85

    PubMed  CAS  Google Scholar 

  • Hammel HT, Crawshaw LI, Cabanac HP (1973) The activation of behavioral responses in the regulation of body temperature in vertebrates. In: Schönbaum E, Lomax P (eds) The pharmacology of thermoregulation. Karger, Basel, pp 124–141

    Google Scholar 

  • Harri MNE (1974) The relation between thyroid activity and responsiveness to adrenaline during cold acclimation in the frog, Rana temporaria. Comp Gen Pharmacol 5:305–309

    Google Scholar 

  • Horseman ND, Meier AH (1978) Prostaglandin and the osmoregulatory role of prolactin in a teleost. Life Sei 22:1485–1490

    CAS  Google Scholar 

  • Huey RB, Stevenson RD (1979) Integrating thermal physiology and ecology of ectotherms: a discussion of approaches. Am Zool 19:357–366

    Google Scholar 

  • Hulbert A J (1978) The thyroid hormones: a thesis concerning their action. J Theor Biol 73:81–100

    PubMed  CAS  Google Scholar 

  • Jacob J, Girault JM, Peindaries R (1972) Actions of 5-hydroxytryptamine and 5-hydroxy-tryptophan injected by various routes on the rectal temperature of the rabbit. Neuropharmacology 11:1–16

    PubMed  CAS  Google Scholar 

  • Javaid MY (1972) Effect of DDT on temperature selection of some salmonids. Pak J Sei Ind Res 15:171–172

    CAS  Google Scholar 

  • Javaid MY, Anderson JM (1967) Influence of starvation on selected temperatures of some salmonids. J Fish Res Board Can 24:1515–1519

    Google Scholar 

  • Kluger MJ (1977) Fever in the frogHyla cinerea. J Therm Biol 2:79–81

    Google Scholar 

  • Kluger MJ (1978) The evolution and adaptive value of fever. Am Sei 66:38–43

    CAS  Google Scholar 

  • Kluger MJ (1979) Fever in ectotherms: evolutionary implications. Am Zool 19:295–304

    CAS  Google Scholar 

  • Kluger MJ, Rothenburg BA (1979) Fever and reduced iron: their interaction as a host defense response to bacterial infection. Science 203:374–376

    PubMed  CAS  Google Scholar 

  • Kluger MJ, Ringler DH, Anver MR (1975) Fever and survival. Science 188:166–168

    PubMed  CAS  Google Scholar 

  • Lagerspetz KYH, Harri MNE, Okslahti R (1974) The role of the thyroid in the temperature acclimation of the oxidative metabolism in the frogRana temporia. Gen Comp Endocrinol 22:169–176

    PubMed  CAS  Google Scholar 

  • Lilly white HB, Licht P, Chelgren P (1973) The role of behavioral thermoregulation in the growth energetics of the toad, Bufo boreas. Ecology 54:375–383

    Google Scholar 

  • Lotti VJ (1973) Body temperature responses to morphine. In: Schönbaum E, Lomax P (eds) The pharmacology of thermoregulation. Karger, Basel, pp 236–244

    Google Scholar 

  • Louw G, Young BA, Bligh J (1976) Effect of thyroxine and noradrenaline on thermoregulation, cardiac rate and oxygen consumption in the monitor lizard Varanus albigularis albigularis. J Therm Biol 1:189–193

    CAS  Google Scholar 

  • Malvin MD, Kluger MJ (1979) Oxygen uptake in green iguana (Iguana iguana) injected with bacteria. J Therm Biol 4:147–148

    Google Scholar 

  • McCauley RW, Reynolds WW, Huggins NH (1977) Photokinesis and behavioral thermoregulation in adult sea lampreys (Petromyzon marinus). J Exp Zool 202:431–437

    Google Scholar 

  • McKeown BA, Peter RE (1976) The effects of photoperiod and temperature on the release of prolactin from the pituitary gland of the goldfish. Can J Zool 54:1960–1969

    PubMed  CAS  Google Scholar 

  • Meier AH (1970) Thyroxin phases the circadian fattening response of goldfish to prolactin. Proc Soc Exp Biol Med 133:1113–1116

    PubMed  CAS  Google Scholar 

  • Miller DL, Ogilvie DM (1975) Temperature selecton in the brook trout (Salvelinus fon- tinalis) following exposure to DDT, PCB and phenol. Bull Environ Contam Toxicol 14:545–551

    Google Scholar 

  • Milton AS, Wendlandt S (1970) A possible role of prostaglandin as a modulator for temperature regulation in the central nervous system of the cat. J Physiol (Lond) 207:76–77P

    Google Scholar 

  • Milton AS, Wendlandt S (1971) Effects on body temperature of prostaglandins of the A, E, and F series on injection into the third ventricle of unanaesthetized cats and rabbits. J Physiol (Lond) 218:325–336

    CAS  Google Scholar 

  • Mueller R (1976) Investigations on the body temperature of freshwater fishes. Arch Fischereiwiss 27:1–28

    Google Scholar 

  • Myers RD (1977) New aspects of the role of hypothalamic calcium ions, 5-HT and PGE during normal thermoregulation and pyrogen fever. In: Cooper KW, Lomax P, Schönbaum E (eds) Drugs, biogenic amines and body temperature. Karger, Basel, pp 374–386

    Google Scholar 

  • Myers RD, Simpson CW, Higgins D, Natterman RA, Rice JC, Redgrave P, Metealf G (1976) Hypothalamic Na+ and Ca+ + ions and temperature set-point: new mechanisms of action of a central of peripheral thermal challenge and intrahypothalamic 5-HT, NE, PGEi and pyrogen. Brain Res Bull 1:301–327

    CAS  Google Scholar 

  • Myhre K (1978) Behavioral temperature regulation in neonate chick of bantam hen (Gallus domesticus). Poultry Sei 57:1369–1375

    CAS  Google Scholar 

  • Myhre K, Cabanac M, Myhre G (1977) Fever and behavioural temperature regulation in the frog Rana esculenta. Acta Physiol Scand 101:219–229

    PubMed  CAS  Google Scholar 

  • Nagai M, Iriki M (1978) Autonomic response of the fish to pyrogen. Experientia 34:1177–1178

    PubMed  CAS  Google Scholar 

  • Nakaoka Y, Oosawa F (1977) Temperature-sensitive behavior ofParamecium caudatum. J Protozool 24:575–580

    Google Scholar 

  • Nistico G, Rotiroti D (1978) Antipyretics and fever induced in adult fowls by prostaglandinsE1 E2 and O somatic antigen. Neuropharmacology 17:197–204

    PubMed  CAS  Google Scholar 

  • Ogilvie DM, Anderson JM (1965) Effect of DDT on temperature selection by young Atlantic salmon, Salmo salar. J Fish Res Board Can 22:503–512

    CAS  Google Scholar 

  • Ogilvie DM, Fryer JN (1971) Effect of sodium pentobarbitol on the temperature selection response of guppies (Poecilia reticulata). Can J Zool 49:949–951

    PubMed  CAS  Google Scholar 

  • Opuszynski K (1971) Temperature preference of fathead minnow (Pimephales promelas Raf.) and its changes induced by copper salt CuSO4. Pol Arch Hydrobiol 18:401–408

    CAS  Google Scholar 

  • Peter RE McKeown BA (1975) Hypothalamic control of prolactin and thyrotropin secretion in teleosts, with special reference to recent studies on the goldfish. Gen Comp Endocrinol 25:153–165

    Google Scholar 

  • Peterson RH (1973a) Temperature selection of juvenile Atlantic salmon (Salmo salar) and brook trout (Salvelinus fontinalis) as influenced by various chlorinated hydrocarbons. J Fish Res Board Can 30:1091–1097

    CAS  Google Scholar 

  • Peterson RH (1973b) Temperature selection of juvenile Atlantic salmon (Salmo salar L.) exposed to some pesticides. Fish Res Board Can MS Rep Ser 1251:1–9

    Google Scholar 

  • Peterson RH (1976) Temperature selection of juvenile Atlantic salmon (Salmo salar) as influenced by various toxic substances. J Fish Res Board Can 33:1722–1730

    CAS  Google Scholar 

  • Pittman OJ, Veale WL, Cockeram AW, Cooper KE (1976) Changes in body temperature produced by prostaglandins and pyrogens in the chicken. Am J Physiol 230:1284–1287

    PubMed  CAS  Google Scholar 

  • Polk DK, Lipton JM (1975) Effects of sodium salicylate, aminopyrine and chlorpromazine on behavioral temperature regulation. Pharmacol Biochem Behav 3:167–172

    PubMed  CAS  Google Scholar 

  • Ralph CL, Firth BT, Turner JS (1979) The role of the pineal body in ectotherm thermoregulation. Am Zool 19:273–293

    CAS  Google Scholar 

  • Regal PJ (1966) Thermophilic response following feeding in certain reptiles. Copeia 1966:588–590

    Google Scholar 

  • Regal PJ (1967) Voluntary hypothermia in reptiles. Science 155:1551–1553

    PubMed  CAS  Google Scholar 

  • Reynolds WW (1977a) Thermal equilibration rates in relation to heartbeat and ventilatory frequencies in largemouth blackbass, Micropterus salmoides. Comp Biochem Physiol [A] 56:195–201

    CAS  Google Scholar 

  • Reynolds WW (1977b) Temperature as a proximate factor in orientation behaviour. J Fish Res Board Can 34:734–739

    Google Scholar 

  • Reynolds WW (1977c) Fever and antipyresis in the bluegill sunfish, Lepomis macrochirus. Comp Biochem Physiol [C] 57:165–167

    CAS  Google Scholar 

  • Reynolds WW (1977d) Circadian rhythms in the goldfish Carassius auratus L.: preliminary observations and possible implications. Rev Can Biol 36:355–356

    Google Scholar 

  • Reynolds WW (1979) Perspective and introduction to the symposium: thermoregulation in ectotherms. Am Zool 19:193–194

    Google Scholar 

  • Reynolds WW, Casterlin ME (1976) Thermal preferenda and behavioral thermoregulation in three centrarchid fishes. In: Esch GW, McFarlane RW (eds) Thermal ecology II. US National Technical Information Service, Springfield, Va, pp 185–190

    Google Scholar 

  • Reynolds WW, Casterlin ME (1977) Temperature preferences of four fish species in an electronic thermoregulatory shuttlebox. Prog Fish-Cult 39:123–125

    Google Scholar 

  • Reynolds WW, Casterlin ME (1978a) Estimation of cardiac output and stroke volume from thermal equilibration and heartbeat rates in fish. Hydrobiologia 57:49–52

    Google Scholar 

  • Reynolds WW, Casterlin ME (1978b) Behavioral thermoregulation and diel activity in white sucker (Catostomus commersoni). Comp Biochem Physiol [A] 59:261–262

    Google Scholar 

  • Reynolds WW, Casterlin ME (1978c) Thermoregulatory behavior in the smooth dogfish shark, Mustelus canis. Fed Proc 37:427

    Google Scholar 

  • Reynolds WW, Casterlin ME (1978d) Behavioral thermoregulation by ammocoete larvae of the sea lamprey (Petromyzon marinus) in an electronic shuttlebox. Hydrobiologia 61:145–147

    Google Scholar 

  • Reynolds WW, Casterlin ME (1978e) Complementarity of thermoregulatory rhythms in Micropterus salmoides and M. dolomieui. Hydrobiologia 60:89–91

    Google Scholar 

  • Reynolds WW, Casterlin ME (1979) Behavioral thermoregulation and the “final prefer-endum” paradigm. Am Zool 19:211–224

    Google Scholar 

  • Reynolds WW, Casterlin ME (1980) The role of fever in aquatic vertebrates. In: Cox B, Lomax P, Milton AS, Schönbaum E (eds) Thermoregulatory mechanisms and their therapeutic implications. Karger, Basel, pp 148–151

    Google Scholar 

  • Reynolds WW, Covert JB (1977) Behavioral fever in aquatic ectothermic vertebrates. In: Cooper KE, Lomax P, Schönbaum E (eds) Drugs, biogenic amines and body temperature. Karger, Basel, pp 108–110

    Google Scholar 

  • Reynolds WW, Casterlin ME, Covert JB (1976a) Behavioural fever in teleost fishes. Nature 259:41–42

    PubMed  CAS  Google Scholar 

  • Reynolds WW, McCauley RW, Casterlin ME, Crawshaw LI (1976b) Body temperatures of behaviorally thermoregulating largemouth blackbass (Micropterus salmoides). Comp Biochem Physiol [A] 54:461–463

    CAS  Google Scholar 

  • Reynolds WW, Casterlin ME, Covert JB (1978a) Febrile responses of bluegill (Lepomis macrochirus) to bacterial pyrogens. J Therm Biol 3:129–130

    Google Scholar 

  • Reynolds WW, Casterlin ME, Matthey JK, Millington ST, Ostrowski AC (1978b) Diel patterns of preferred temperature and locomotor activity in the goldfish Carassius auratus. Comp Biochem Physiol [A] 59:225–227

    Google Scholar 

  • Reynolds WW, Covert JB, Casterlin ME (1978c) Febrile responses of goldfish Carassius auratus to Aeromonas hydrophila and to Escherichia coli endotoxin. J Fish Dis 1:271–273

    Google Scholar 

  • Reynolds WW, Casterlin ME, Covert JB (1979) Comparative thermoregulatory and febrile behavior of aquatic ectothermic vertebrates and arthropods. Fed Proc 38:1053

    Google Scholar 

  • Reynolds WW, Casterlin ME, Covert JB (1980) Behaviorally mediated fever in aquatic ec-totherms. In: Lipton JM (ed) Fever. Raven, New York, pp 207–212

    Google Scholar 

  • Reynolds WW, Casterlin ME, Spieler RE (1982) Thyroxine: effect on behavioral thermoregulation in fishes. Can J Zool 60:926–928

    CAS  Google Scholar 

  • Roth J J, Ralph CL (1977) Thermal and photic preferences in intact and parietalectomized Anolis carolinensis., Behav Biol 19:341–348

    PubMed  CAS  Google Scholar 

  • Satinoff E (1972) Salicylate: action on normal body temperature in rats. Science 176:532–533

    PubMed  CAS  Google Scholar 

  • Satinoff E, McEwen GN Jr, Williams BA (1976) Behavioral fever in newborn rabbits. Science 193:1139–1140

    PubMed  CAS  Google Scholar 

  • Saxena PN (1976) Sodium and calcium ions in the control of temperature set-point in the pigeon. Br J Pharmacol 56:187–192

    PubMed  CAS  Google Scholar 

  • Smith EN (1979) Behavioral and physiological thermoregulation of crocodilians. Am Zool 19:239–247

    Google Scholar 

  • Spieler RE, Noeske TA (1979) Diel variations in circulating levels of triiodothyronine and thyroxine in goldfish. Can J Zool 57:665–669

    CAS  Google Scholar 

  • Spieler RE, Noeske TA, deVlaming VL, Meier AH (1977) Effects of thermocycles on body weight gain and gonadal growth in the goldfish,Carassius auratus.Trans Am Fish Soc 106:440–444

    Google Scholar 

  • Stern RC (1977) Pathophysiologic basis for sympatric treatment of fever. Pediatrics 59:92–98

    PubMed  CAS  Google Scholar 

  • Stevens ED, Fry FE J (1970) The rate of thermal exchange in a teleost, Tilapia mossambica.Can J Zool 48:221–226

    PubMed  CAS  Google Scholar 

  • Stevens ED, Fry FE J (1974) Heat transfer and body temperatures in non-thermoregulatory teleosts. Can J Zool 52:1137–1145

    PubMed  CAS  Google Scholar 

  • Stuntz WE, Magnuson J J (1976) Daily ration, temperature selection and activity of bluegill. In: Esch GW, McFarlane RW (eds) Thermal ecology II. US National Technical Information Service, Springfield, VA, pp 180–184

    Google Scholar 

  • Takahara J, Mori M, Ofuji N et al. (1977) Effects of prostaglandin E1 and indomethacin on ACTH, prolactin, GH and LH from the rat pituitary in vitro. Endocrinol Jpn 24:97–103

    PubMed  CAS  Google Scholar 

  • Tonque T (1977) TRH: a possible mediator of behavioral thermoregulation in neonatal chicken. Proc Int Union Physiol Sei 13:757

    Google Scholar 

  • Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirinlike drugs. Nature 231:232–235

    CAS  Google Scholar 

  • Van Miert ASJPAM, Frens J (1968) The reaction of different animal species to bacterial pyrogens. Zentral Veterinaer med 15:532–543

    Google Scholar 

  • Vaughn LK, Bernheim HA, Kluger MJ (1974) Fever in the lizard Dipsosaurus dorsalis. Nature 252:473–474

    PubMed  CAS  Google Scholar 

  • Veale WL, Cooper KE Pittman QJ (1977) Role of prostaglandins in fever and temperature regulation. In: Ramwell PW (ed) The prostaglandins, vol 3. Plenum, New York, pp 145–167

    Google Scholar 

  • Von Euler US (1961) Occurrence and distribution of catecholamines in the fish brain. Acta Physiol Scand 52:62–64

    Google Scholar 

  • Weiss B, Laties VG (1963) Effects of amphetamines, chlorpromazine and pentobarbitol on behavioral thermoregulation. J Pharmacol Exp Ther 140:1–7

    PubMed  CAS  Google Scholar 

  • Welsh JH (1968) Distribution of serotonin in the nervous system of various animal species. Adv Pharmacol 6:71–88

    Google Scholar 

  • Wigham T, Nishioka RS, Bern HA (1977) Factors affecting in vitro activity of prolactin cells in the euryhaline teleost Sarotherodon mossambicus (Tilapia mossambica). Gen Comp Endocrinol 32:120–131

    PubMed  CAS  Google Scholar 

  • Wodtke E (1978) Lipid adaptation in liver mitochondrial membranes of carp acclimated to different environmental temperatures: phospholipid composition, fatty acid pattern, and cholesterol content. Biochim Biophys Acta 529:280–291

    PubMed  CAS  Google Scholar 

  • Yakovleva IV, Komachkova ZK (1978) Hypothalamo-hypophyseal neurosecretory system and the thyroid in the parr of the sturgeon Acipenser guldenstadti during variation in environmental temperature. Zh Evol Biokhim Fiziol 14:175–179

    Google Scholar 

  • Ziel R, Krupp P (1976) Mechanisms of action of antipyretic drugs. In: Brazier MAB, Co-ceani F (eds) Brain dysfunction in infantile febrile convulsions. Raven, New York, pp 153–160

    Google Scholar 

  • Zeihuisen H (1895) Beiträge zur Lehre der Immunität und Idiosynkrasie. I. Über den Einfluß der Körpertemperatur auf die Wirkung einiger Gifte an Tauben. Arch Exp Pathol Pharmakol 35:181–212

    Google Scholar 

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Reynolds, W.W., Casterlin, M.E. (1982). The Pyrogenic Responses of Non-mammalian Vertebrates. In: Milton, A.S. (eds) Pyretics and Antipyretics. Handbook of Experimental Pharmacology, vol 60. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68569-9_19

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