The Treatment of Fever from a Clinical Viewpoint

  • C. A. Dinarello
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 60)


In most clinical settings, the reduction of elevated body temperature is a routine procedure. During the past 200 years, increasingly more sophisticated pharmacological agents have expanded our ability to reduce body temperature, while several physical methods have been available for over 25 centuries. Despite the variety of procedures which can lower body temperature, treatment should be appropriate for the particular clinical problem. For example, the physician who is treating a patient with a febrile illness considers whether reducing the fever will obscure information concerning the progress of the disease or the effectiveness of a particular drug. Other aspects which should be considered include the physical status of the patient, the cause of the temperature elevation, and whether the elevation of body temperature is harmful to the patient.


Febrile Seizure Heat Stroke Elevated Body Temperature Clinical Viewpoint Endogenous Pyrogen 
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© Springer-Verlag Berlin Heidelberg 1982

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  • C. A. Dinarello

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