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The Chemistry of the Non-Steroidal Antipyretic Agents: Structure-Activity Relationships

  • Chapter
Pyretics and Antipyretics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 60))

  • 186 Accesses

Abstract

For a long time human fever has been considered to be a result of an alteration in the body’s thermostat in the hypothalamus, in response to a variety of pyrogenic factors such as bacteria, viruses and fungi. Inflammation, caused by whatever means, has also been thought to cause similar alterations of the thermostat, resulting in fever (Feldberg and Milton 1979). These febrile responses have been considered to be a defence mechanism of the body against such foreign invaders.

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Authors
  1. D. H. Kim
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  2. C. G. Van Arman
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  3. D. Armstrong
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Editors and Affiliations

  1. Department of Pharmacology, University of Aberdeen, Marischal College, AB9 1AS, Aberdeen, Scotland, Great Britain

    Anthony S. Milton

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© 1982 Springer-Verlag Berlin Heidelberg

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Kim, D.H., Van Arman, C.G., Armstrong, D. (1982). The Chemistry of the Non-Steroidal Antipyretic Agents: Structure-Activity Relationships. In: Milton, A.S. (eds) Pyretics and Antipyretics. Handbook of Experimental Pharmacology, vol 60. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68569-9_12

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  • DOI: https://doi.org/10.1007/978-3-642-68569-9_12

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