Abstract
The process of implantation of the blastocyst in utero in the mouse is normally triggered by oestradiol-17β. It can, however, be prevented by the drug tamoxifen whose actions in other species are classified as anti-oestrogenic, but which the mouse is held to be a weak oestrogen. Results are presented which support the claim that the anti-implantation action of tamoxifen is dose dependent, oestrogenicity dominating at high doses and anti-oestrogenicity being of major importance at lower doses.
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References
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© 1982 Springer-Verlag
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Pugh, D.M., Sumano, H.S. (1982). The Anti-Implantation Action of Tamoxifen in Mice. In: Chambers, C.M., Chambers, P.L. (eds) New Toxicology for Old. Archives of Toxicology, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68511-8_38
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DOI: https://doi.org/10.1007/978-3-642-68511-8_38
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-11406-2
Online ISBN: 978-3-642-68511-8
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