Effects of Diet Substituted in Protein Components on the Fertility and on Postnatal Growth and Behaviour of Rats

  • E. Chiesara
  • F. Clementi
  • A. Bizzi
  • L. Marabini
Conference paper
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 5)

Abstract

A long term treatment, carried out on the rat using diet with 50–60% of the protein content substituted with proteins obtained from algae (Spirulina), causes a reduced fertility.

However it does not cause any modification of the course of pregnancy or of the postnatal development of the litters, apart from an increased benzopyrene hydroxylase activity in the hepatic microsomes of the newborn. The activity returns to normal shortly after weaning.

Key words

Diet Spirulina Alga Fertility Microsomes 

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References

  1. Chiesara E, Bizzi A, Clementi F, Della Torre P, Marabini L, Rizzi R, Villa A (1980) Trattamenti prolungati nel ratto con diete contenenti proteine algali (Spirulina). Aspetti biochimici, morfologici e tossicologici. Proceeding of symposium “Prospettive della coltura di spirulina in Italia” November 20–21, 1980Google Scholar
  2. Chiesara E, Bizzi A, Clementi F, Della Torre P, Marabini L (1981) Morphological aspects of kidney of animals fed on proteins from algae. Gen Pharmacol 12: A41Google Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • E. Chiesara
    • 1
  • F. Clementi
    • 2
  • A. Bizzi
    • 3
  • L. Marabini
    • 2
  1. 1.Department of PharmacologyChair of ToxicologyMilanoItaly
  2. 2.CNR Center of CitopharmacologyMilanoItaly
  3. 3.“M. Negri” InstituteMilanoItaly

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