Abstract
The behavioural symptoms of acute p-benzoquinone intoxication in the cockroach were shown to be an initial excitation followed by rigid paralysis. p-Benzoquinone produced a depolarization of the postsynaptic membrane of the giant neurones in the 6th abdominal ganglion of the cockroach which was accompanied by an increase in the electrically evoked excitatory postsynaptic potential. The frequency and amplitude of unitary postsynaptic potentials also increased. These effects may be due to inhibition of active cation transport, as illustrated here on the frog isolated skin.
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Abbreviations
- CNS:
-
central nervous system
- n :
-
number of preparations studied
- EPSP:
-
excitatory postsynaptic potential
- IPSP:
-
inhibitory postsynaptic potential
- GABA:
-
γ-amino butyric acid
- (Na,K)-ATPase:
-
sodium, potassium adenosine triphosphatase
- ISC :
-
short-circuit current
- VM :
-
transmembrane potential
- Rm :
-
transmembrane resistance
- RMP:
-
resting membrane potential
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© 1982 Springer-Verlag
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Chambers, P.L., Rowan, M.J. (1982). The Toxicity of p-Benzoquinone on the Central Nervous System of the Cockroach. In: Chambers, C.M., Chambers, P.L. (eds) New Toxicology for Old. Archives of Toxicology, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68511-8_19
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DOI: https://doi.org/10.1007/978-3-642-68511-8_19
Publisher Name: Springer, Berlin, Heidelberg
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