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Grundlagen

  • Conference paper
Notfalltherapie

Part of the book series: Interdisziplinäre Gastroenterologie ((GASTROENTEROLOG))

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Zusammenfassung

Toxische Colondilatationen (toxisches Megacolon) sind als Komplikation ulceröser und granulomatosa Colitiden selten. Das klinische Bild des toxischen Megacolons wird beherrscht durch hohes Fieber, profuse Durchfälle, durch Störungen des Wasser-, Eiweiß- und Elektrolythaushaltes, oft durch eine ausgeprägte Lethargie der Patienten [18]. Das häufig kombinierte Auftreten mit Perforationen und profusen, unstillbaren Blutungen erklärt die hohe Mortalität dieser „darmeigenen“ Komplikationen chronisch-entzündlicher Dickdarmerkrankungen [5, 21, 22, 27, 29, 33, 35, 61, 64].

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Literatur

  1. Adler HF, Atkinson AJ, Ivy AC (1942) Effect of morphine and dilaudid on the ileum, and of morphine, dilaudid and atropine on the colon of man. Arch Intern Med 69:974

    Google Scholar 

  2. Balslev I, Jensen HE, Norgaard F, Poll P (1970) Ischemic Colitis. Acta Chir Scand 136:235–242

    PubMed  CAS  Google Scholar 

  3. Barron RA, Jarkowski TL, Ruel RE (1964) Ileocolitis, the importance of a more precise definition. Am J Dig Dis 9:862–871

    Article  PubMed  CAS  Google Scholar 

  4. Bartlett JG (1981) Clostridium difficile and inflammatory bowel disease. Gastroenterology 80:863–865

    PubMed  CAS  Google Scholar 

  5. Binder SC, Patterson JF, Glotzer DJ (1974) Toxic megacolon in ulcerative Colitis. Gastroenterology 66:909–915

    PubMed  CAS  Google Scholar 

  6. Bockus HL, Roth JLA, Buchman E, Kaiser M (1958) Ulcerative Colitis. I. Classification of types, clinical behavior, life history, prognosis. In:Jones FA (ed) Modern trends in gastroenterology, vol 2. Hoeker, New York, p 296

    Google Scholar 

  7. Brown JW (1979) Toxic megacolon associated with Loperamide therapy. JAMA 241:501–502

    Article  PubMed  CAS  Google Scholar 

  8. Buckell NA, Williams GT, Bartram CI, Lennard-Jones JE (1980) Depth of ulceration in acute Colitis. Correlation with outcome and clinical and radiologic features. Gastroenterology 79:19–25

    PubMed  CAS  Google Scholar 

  9. Buzzard AJ, Baker WNW, Needham PRG, Warren RE (1974) Acute toxic dilatation of the colon in Crohn’s Colitis. Gut 15:416–419

    Article  PubMed  CAS  Google Scholar 

  10. Cardosa JM, Kimura K, Stoopen M, Cervantes LF, Elizondo L, Churchill R, Moncada R (1977) Radiology of invasive amoebiasis of the colon. Am J Roentgenol 128:935–941

    Google Scholar 

  11. Case Records of the Massachusetts General Hospital, Case 19023, 23201, 27242. N Engl J Med 208:94 (1933); 216:894–896 (1937); 224:1029–1031 (1941)

    Google Scholar 

  12. Cohn EM, Copit P, Turnen HJ (1965) Ulcerative Colitis with hypopotassemia. Gastroenterology 30:950–957

    Google Scholar 

  13. Crile G, Thomas CY (1951) The treatment of acute toxic ulcerative Colitis by ileostomy and simultaneous colectomy. Gastroenterology 19:58–68

    PubMed  Google Scholar 

  14. DeDombal FT, Watts JM, Watkinson G, Goligher JC (1965) Ulcerative Colitis and pregnancy. Lancet 11:599–602

    Article  Google Scholar 

  15. Edwards FC, Truelove SC (1964) The course and prognosis of ulcerative Colitis. Part III:Complications. Gut 5:1–15

    Article  PubMed  CAS  Google Scholar 

  16. Ewerwahn WJ, Winkler R (1977) Die zweizeitige chirurgische Therapie der akuten komplizierten Colitis ulcerosa. Indikation, Erfahrungen und Ergebnisse. Dtsch Med Wochenschr 102:860–865

    Article  PubMed  CAS  Google Scholar 

  17. Faegenburg D, Cheal H, Mandel PR, Ross ST (1967) Toxic megacolon in amoebic Colitis. A case report. Am J Roentgenol 99:74–76

    CAS  Google Scholar 

  18. Fahrländer H, Bianchi L Mihatsch MJ (1979) Die chronisch entzündlichen Darmkrankheiten. Ergeb Inn Med Kinderheilkd 42:1–111

    Article  PubMed  Google Scholar 

  19. Farmer RG, Hawk WA, Turnbull RB (1968) Regional enteritis of the colon:A clinical and pathologic comparison with ulcerative Colitis. Am J Dig Dis 13:501–514

    Article  PubMed  CAS  Google Scholar 

  20. Fazio VW (1980) Toxic megacolon in ulcerative Colitis and Crohn’s Colitis. Clin Gastroenterol 9:389–407

    PubMed  CAS  Google Scholar 

  21. Fazio VW, Turnbull RB, Goldsmith MG (1976) Ileostomy-colostomy for the mega-colon phase of toxic ulcerative Colitis. In:Harris R, Clearfield MD, Dinoso VP (eds) Gastrointestinal emergencies. Grüne & Stratton, New York, p 209–219

    Google Scholar 

  22. Flatmark A, Fretheim B, Gjone E (1975) Early colectomy in severe ulcerative Colitis. Scand J Gastroenterol 10:427–431

    PubMed  CAS  Google Scholar 

  23. Garrett JM, Sauer WG, Moertel CG (1967) Colonic motility in ulcerative Colitis after Opiate administration. Gastroenterology 53:93–100

    PubMed  CAS  Google Scholar 

  24. Gebbers JO, Otto HF (1978) Evidence for local immune complexes in ulcerative Colitis. Acta Gastroenterol Belg 41:329–350

    PubMed  CAS  Google Scholar 

  25. Giacchino JL, Pickleman J, Bartizal JF, Banich FE (1978) The therapeutic dilemma of acute amoebic and ulcerative Colitis. Surg Gynecol Obstet 146:599–603

    PubMed  CAS  Google Scholar 

  26. Gloor F (im Druck) Die nicht klassifizierbaren ulcerösen Colitiden. Schweiz Med Wochenschr

    Google Scholar 

  27. Goligher JC, Hoffman DC, DeDombal FT (1970) Surgical treatment of severe attacks of ulcerative Colitis, with special reference to the advantages of early operation. Br Med J 4:703–706

    Article  PubMed  CAS  Google Scholar 

  28. Greenstein AJ, Kark AE, Dreiling DA (1975) Crohn’s disease of the colon. III. Toxic dilatation of the colon in Crohn’s Colitis. Am J Gastroenterol 63:117–128

    PubMed  CAS  Google Scholar 

  29. Heberer G, Hoffmann K, Bary S v (1976) Operative Behandlung entzündlicher Dickdarmerkrankungen:Colitis ulcerosa, Morbus Crohn, Divertikulitis. Dtsch Med Wochenschr 101:605–611

    Article  PubMed  CAS  Google Scholar 

  30. Hoogland T, Cooperman AM, Farmer RG, Fazio VW (1977) Toxic megacolon — unusual complication of pseudomembranous Colitis. Cleve Clin Q 44:149–155

    PubMed  CAS  Google Scholar 

  31. Hywel Jones J, Chapman M (1969) Definition of megacolon in Colitis. Gut 10:562–564

    Article  Google Scholar 

  32. Jalan KN, Sircus W, Card WI et al. (1969) An experience of ulcerative Colitis. I. Toxic dilatation in 55 cases. Gastroenterology 57:68–82

    PubMed  CAS  Google Scholar 

  33. Jalan KN, Prescott RJ, Sircus W et al. (1970) An experience of ulcerative Colitis. III. Long term outcome. Gastroenterology 59:598–609

    PubMed  CAS  Google Scholar 

  34. Juhlin L, Krause U, Shelley WB (1980) Endotoxin-induced microclots in ulcerative Colitis and Crohn’s disease. Scand J Gastroenterol 15:311–314

    Article  PubMed  CAS  Google Scholar 

  35. Koudahl G, Kristensen M (1975) Toxic megacolon in ulcerative Colitis. Scand J Gastroenterol 10:417–421

    PubMed  CAS  Google Scholar 

  36. Lumb G, Protheroe RHB, Ramsay GS (1955) Ulcerative Colitis with dilatation of the colon. Br J Surg 43:182–188

    Article  PubMed  CAS  Google Scholar 

  37. Madison MS, Bargen JA (1951) Fulminating ulcerative Colitis with unusual segmental dilatation of the colon:Report of a case. Mayo Clin Proc 26:21–24

    CAS  Google Scholar 

  38. Marshak RH, Lester LJ, Friedman AI (1950) Megacolon, a complication of ulcerative Colitis. Gastroenterology 16:768–772

    PubMed  CAS  Google Scholar 

  39. Marshak RH, Korelitz BI, Klein SH, Wolf BS, Janowitz HD (1960) Toxic dilation of the colon in the course of ulcerative Colitis. Gastroenterology 38:165–180

    PubMed  CAS  Google Scholar 

  40. McConnell F, Hanelin J, Robbins LL (1958) Piain film diagnosis of fulminating ulcerative Colitis. Radiology 71:674–681

    PubMed  CAS  Google Scholar 

  41. Mclnerney GT, Sauer WG, Baggenstoss AH, Hodgson JR (1962) Fulminating ulcerative Colitis with marked colonic dilation:A clinicopathologic study. Gastroenterology 42:244–256

    Google Scholar 

  42. Meyers S, Mayer L, Bottone E, Desmond E, Janowitz HD (1981) Occurrence of Clostridium difficile toxin during the course of inflammatory bowel disease. Gastroenterology 80:697–700

    PubMed  CAS  Google Scholar 

  43. Mogan GR, Sachar DB, Bauer J, Salky B, Janowitz HD (1980) Toxic megacolon in ulcerative Colitis complicated by Pneumomediastinum:Report of two cases. Gastroenterology 79:559–562

    PubMed  CAS  Google Scholar 

  44. Neschis M, Siegelman SS, Parker JG (1968) Diagnosis and management of the mega-colon of ulcerative Colitis. Gastroenterology 55:251–259

    PubMed  CAS  Google Scholar 

  45. Norland CC, Kirsner JB (1969) Toxic dilatation of colon (toxic megacolon):Etiology, treatment and prognosis in 42 patients. Medicine (Baltimore) 48:229–250

    Article  CAS  Google Scholar 

  46. Odyniec NA, Judd ES, Sauer WG (1967) Toxic megacolon:Significant improvement in surgical management. Arch Surg 94:638–641

    PubMed  CAS  Google Scholar 

  47. Oehmichen M, Reifferscheid P (1977) Intramural ganglion cell degeneration in inflammatory bowel disease. Digestion 15:482–496

    Article  PubMed  CAS  Google Scholar 

  48. Otto HF, Gebbers JO (1981) Electron microscopic, ultracytochemical and immunohistological observations in Crohn’s disease of the ileum and colon. Virchows Arch [Pathol Anat] 391:189–205

    Article  CAS  Google Scholar 

  49. Papp JP, Pollard HM (1970) Toxic dilatation of the colon in granulomatous Colitis. Report of 2 cases. Am J Dig Dis 15:1105–1113

    Article  PubMed  CAS  Google Scholar 

  50. Posey EL, Bargen JA, Dearing WH, Code CF (1948) The effects of certain so-called antispasmodies on intestinal motility. Gastroenterology 11:344

    PubMed  CAS  Google Scholar 

  51. Price AB (1977) Difficulties in the differential diagnosis of ulcerative Colitis and Crohn’s disease. In:Yardley JH, Morson BC, Abell MR (eds) The gastrointestinal tract (International Academy of Pathology Monograph, No 18, p 1–14 ). Williams & Wilkins, Baltimore

    Google Scholar 

  52. Price AB (1978) Overlap in the spectrum of non-specific inflammatory bowel disease — Colitis indeterminate. J Clin Pathol 31:567–577

    Article  PubMed  CAS  Google Scholar 

  53. Prohaska JV, Greer D, Ryan JF (1964) Acute dilatation of the colon in ulcerative Colitis. Arch Surg 89:24–30

    PubMed  CAS  Google Scholar 

  54. Rosato EF, Rosato FG, Scott J (1969) Ischaemic dilatation of the colon. Am J Dig Dis 14:922–928

    Article  PubMed  CAS  Google Scholar 

  55. Rosen IB, Cooter NB, Ruderman RL (1973) Necrotizing Colitis. Surg Gynecol Obstet 137:645–649

    PubMed  CAS  Google Scholar 

  56. Roth JLA, Valdes-Dapena A, Stein GN, Bockus HL (1959) Toxic megacolon in ulcerative Colitis. Gastroenterology 37:239–255

    PubMed  CAS  Google Scholar 

  57. Roth JLA, Stitcher JE, Stein GN, Valdes-Dapena A (1975) Toxic megacolon complicating ulcerative Colitis. In:Lukash WM, Johnson RB (eds) The systemic manifestations of inflammatory bowel disease. Thomas, Springfield III, p 133–175

    Google Scholar 

  58. Schachter H, Goldstein MJ, Kirsner JB (1967) Toxic dilation complicating Crohn’s disease of the colon. Gastroenterology 53:136–142

    PubMed  CAS  Google Scholar 

  59. Schofield PF, Mandal BK, Ironside AG (1979) Toxic dilatation of the colon in Salmonella Colitis and inflammatory bowel disease. Br J Surg 66:5–8

    Article  PubMed  CAS  Google Scholar 

  60. Smith FW, Law DH, Nickel WF, Sleisenger MH (1962) Fulminant ulcerative Colitis with toxic dilation of the colon:Medical and surgical management of eleven cases with observations regarding etiology. Gastroenterology 42:233–243

    Google Scholar 

  61. Strauss RJ, Flint GW, Platt N, Levin L, Wise L (1976) The surgical management of toxic dilatation of the colon:A report of 28 cases and review of the literature. Ann Surg 184:682–688

    Article  PubMed  CAS  Google Scholar 

  62. Trnka YM, Lamont JT (1981) Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease. Gastroenterology 80:693–696

    PubMed  CAS  Google Scholar 

  63. Truelove SC, Marks CG (1981) Toxic megacolon. Part I:Pathogenesis, diagnosis and treatment. Clin Gastroenterol 10:107–117

    PubMed  CAS  Google Scholar 

  64. Watts JM, DeDombal FT, Goligher JC (1966) Long-term complications and prognosis following major surgery for ulcerative Colitis. Br J Surg 53:1014–1023

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. H. F. Otto
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Editors and Affiliations

  1. Klinik und Poliklinik für Allgemeinchirurgie, der Georg-August-Universität Göttingen, Robert-Koch-Straße 40, D-3400, Göttingen, Germany

    Jörg Rüdiger Siewert

  2. Medizinische Klinik, Stadtspital Triemli, Birmendorferstraße 497, CH-8063, Zürich, Switzerland

    André Louis Blum

  3. Abteilung für Allgemeine Chirurgie mit Poliklinik, Chirurgische Universitätsklinik, Hugstetterstraße 55, D-7800, Freiburg, Germany

    Eduard H. Farthmann

  4. Abteilung Gastroenterologie und Stoffwechsel, Medizinische Universitätsklinik, Robert-Koch-Straße 40, D-3400, Göttingen, Germany

    Paul G. Lankisch

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© 1982 Springer-Verlag Berlin Heidelberg

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Otto, H.F. (1982). Grundlagen. In: Siewert, J.R., Blum, A.L., Farthmann, E.H., Lankisch, P.G. (eds) Notfalltherapie. Interdisziplinäre Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68497-5_37

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  • DOI: https://doi.org/10.1007/978-3-642-68497-5_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68498-2

  • Online ISBN: 978-3-642-68497-5

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