Skip to main content

Pathogenese

  • Conference paper
Notfalltherapie

Part of the book series: Interdisziplinäre Gastroenterologie ((GASTROENTEROLOG))

  • 23 Accesses

Zusammenfassung

Etwa 80–85% der Magen-Darm-Blutungen stammen aus dem oberen Magen-Darm-Trakt [14]. In den meisten größeren publizierten Studien sind Ulcera duodeni und Ulcera ventriculi die häufigsten Blutungsquellen, gefolgt von Blutungen aus sog. hämorrhagischen Erosionen oder akuten Ulcerationen. Letztere Läsionen entstehen besonders häufig als Folge eines sog. Streßulcussyndroms oder nach Einnahme von entzündungshemmenden Medikamenten, wie vor allem Aspirin und Indomethacin.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Allen A, Garner A (1980) Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection. Gut 21:249–262

    Article  PubMed  CAS  Google Scholar 

  2. Clémençon G, Bürgi W, Kaufmann H (1975) Lysolecithin im Mageninhalt. Z Gastroenterol 13:1–2

    Article  Google Scholar 

  3. Clémençon G, Finger J, Fehr HF (1981) The role of taurocholic acid, glycocholic acid and lysolecithin in experimental stress ulcer in the rat. Scand J Gastroent [Suppl] 67:137–140

    Google Scholar 

  4. Davenport HW (1964) Gastric mucosal injury by fatty and acetylsalicylic acids. Gastroenterology 46:245–253

    PubMed  CAS  Google Scholar 

  5. Davenport HW (1968) Destruction of the gastric mucosal barrier by detergents and urea. Gastroenterology 54:175–181

    PubMed  CAS  Google Scholar 

  6. Davenport HW (1970) Effect of lysolecithin, digitonin and phospholipase A upon the dog’s gastric mucosal barrier. Gastroenterology 59:505–509

    PubMed  CAS  Google Scholar 

  7. Dieulafoy G (1910) A text book of medicine. Appleton, New York, p 674

    Google Scholar 

  8. Dowling RH, Small DM (1968) The effect of pH on the solubility of varying mixtures of free and conjugated bile salts in Solution. Gastroenterology 54:1291

    Google Scholar 

  9. Idjadi F, Robbins R, Stahl WM, Essiet G (1971) Prospective study of gastric secretion in stressed patients with intracranial injury. J Trauma 11:681–688

    Article  PubMed  CAS  Google Scholar 

  10. Ivey KJ, DenBesten L, Clifton JA (1970) Effect of bile salts on ionic movement across the human gastric mucosa. Gastroenterology 59:683–690

    PubMed  CAS  Google Scholar 

  11. Ivy AC, Grossman MI, Bachrach WH (1950) In: (eds) Peptic ulcer. Blakiston, Philadelphia Toronto, p 225–227

    Google Scholar 

  12. Johnson AG, MacDermott SJ (1974) Lysolecithin, a factor in the pathogenesis of gastric ulceration? Gut 15:710–713

    Article  PubMed  CAS  Google Scholar 

  13. Lambling A, Gösset JR (1947) Le reflux des secretions alcalines duodeno-pancreatico-biliaires en Physiopathologie gastrique. Arch Mal Appar Dig Mal Nutr 36:533

    PubMed  CAS  Google Scholar 

  14. Lucas CE (1980) Prevention and treatment of acute gastric erosions and stress ulcerations. In: Fiddian-Green RG, Turcotte JG (eds) Gastrointestinal hemorrhage. Grune and Stratton, New York London Toronto Sydney San Francisco, p 167–188

    Google Scholar 

  15. Norton L, Greer J, Eiseman B (1970) Gastric secretory response to head injury. Arch Surg 101:200–204

    PubMed  CAS  Google Scholar 

  16. Overholt BF, Pollard HM (1968) Acid diffusion into the human gastric mucosa. Gastroenterology 54:182–189

    PubMed  CAS  Google Scholar 

  17. Payne JG, Bowen JC (1981) Hypoxia of canine gastric mucosa caused by escherichia coli sepsis and prevented with methylprednisolone therapy. Gastroenterology 80:84–93

    PubMed  CAS  Google Scholar 

  18. Reimann HJ, Meier HJ, Schmal A, Fischer M, Lorenz A (1977) Adaption und Kreuzadaption an Kälte und Restraint zur Vermeidung von Streßulkus-Bildung bei der weiblichen Ratte. Z Phys Med 6:22–23

    Google Scholar 

  19. Ritchie WP Jr, Shearburn EW (1976) Acute gastric mucosal ulcerogenesis is dependent on the concentration of bile salts. Surgery 80:98–105

    PubMed  CAS  Google Scholar 

  20. Robert A (1979) Cytoprotection by Prostaglandins. Gastroenterology 77:761–767

    PubMed  CAS  Google Scholar 

  21. Scheurer U, Schlegel JF, Kelly DG, Code CF (1981) Chronic bile exposure increases resistance of canine gastric mucosa to bile. Scand J Gastroenterol [Suppl] 67:205–210

    CAS  Google Scholar 

  22. Schumpelick V, Begemann F (1979) DGR und klinische Streßulkus-Gefährdung. In: Schumpelick H, Begemann F, Berndt W (Hrsg) Refluxkrankheit des Magens. Enke, Stuttgart, S 96–103

    Google Scholar 

  23. Stremple JF, Mori H, Lev R, Glass GBJ (1973) The stress ulcer Syndrome. In: (eds) Current problems in surgery year book medical. Publishers, Chicago, p. 33–36

    Google Scholar 

  24. Thjodleifsson B, Wormsley KG (1977) Back-diffusion — fact or fiction? Digestion 15:53–72

    Article  PubMed  CAS  Google Scholar 

  25. Whitfield PF, Hobsley M (1977) Failure to detect back-diffusion in human gastric aspirate. Gut 18:947

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Halter, F. (1982). Pathogenese. In: Siewert, J.R., Blum, A.L., Farthmann, E.H., Lankisch, P.G. (eds) Notfalltherapie. Interdisziplinäre Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68497-5_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68497-5_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68498-2

  • Online ISBN: 978-3-642-68497-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics