Zusammenfassung
Etwa 80–85% der Magen-Darm-Blutungen stammen aus dem oberen Magen-Darm-Trakt [14]. In den meisten größeren publizierten Studien sind Ulcera duodeni und Ulcera ventriculi die häufigsten Blutungsquellen, gefolgt von Blutungen aus sog. hämorrhagischen Erosionen oder akuten Ulcerationen. Letztere Läsionen entstehen besonders häufig als Folge eines sog. Streßulcussyndroms oder nach Einnahme von entzündungshemmenden Medikamenten, wie vor allem Aspirin und Indomethacin.
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Literatur
Allen A, Garner A (1980) Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection. Gut 21:249–262
Clémençon G, Bürgi W, Kaufmann H (1975) Lysolecithin im Mageninhalt. Z Gastroenterol 13:1–2
Clémençon G, Finger J, Fehr HF (1981) The role of taurocholic acid, glycocholic acid and lysolecithin in experimental stress ulcer in the rat. Scand J Gastroent [Suppl] 67:137–140
Davenport HW (1964) Gastric mucosal injury by fatty and acetylsalicylic acids. Gastroenterology 46:245–253
Davenport HW (1968) Destruction of the gastric mucosal barrier by detergents and urea. Gastroenterology 54:175–181
Davenport HW (1970) Effect of lysolecithin, digitonin and phospholipase A upon the dog’s gastric mucosal barrier. Gastroenterology 59:505–509
Dieulafoy G (1910) A text book of medicine. Appleton, New York, p 674
Dowling RH, Small DM (1968) The effect of pH on the solubility of varying mixtures of free and conjugated bile salts in Solution. Gastroenterology 54:1291
Idjadi F, Robbins R, Stahl WM, Essiet G (1971) Prospective study of gastric secretion in stressed patients with intracranial injury. J Trauma 11:681–688
Ivey KJ, DenBesten L, Clifton JA (1970) Effect of bile salts on ionic movement across the human gastric mucosa. Gastroenterology 59:683–690
Ivy AC, Grossman MI, Bachrach WH (1950) In: (eds) Peptic ulcer. Blakiston, Philadelphia Toronto, p 225–227
Johnson AG, MacDermott SJ (1974) Lysolecithin, a factor in the pathogenesis of gastric ulceration? Gut 15:710–713
Lambling A, Gösset JR (1947) Le reflux des secretions alcalines duodeno-pancreatico-biliaires en Physiopathologie gastrique. Arch Mal Appar Dig Mal Nutr 36:533
Lucas CE (1980) Prevention and treatment of acute gastric erosions and stress ulcerations. In: Fiddian-Green RG, Turcotte JG (eds) Gastrointestinal hemorrhage. Grune and Stratton, New York London Toronto Sydney San Francisco, p 167–188
Norton L, Greer J, Eiseman B (1970) Gastric secretory response to head injury. Arch Surg 101:200–204
Overholt BF, Pollard HM (1968) Acid diffusion into the human gastric mucosa. Gastroenterology 54:182–189
Payne JG, Bowen JC (1981) Hypoxia of canine gastric mucosa caused by escherichia coli sepsis and prevented with methylprednisolone therapy. Gastroenterology 80:84–93
Reimann HJ, Meier HJ, Schmal A, Fischer M, Lorenz A (1977) Adaption und Kreuzadaption an Kälte und Restraint zur Vermeidung von Streßulkus-Bildung bei der weiblichen Ratte. Z Phys Med 6:22–23
Ritchie WP Jr, Shearburn EW (1976) Acute gastric mucosal ulcerogenesis is dependent on the concentration of bile salts. Surgery 80:98–105
Robert A (1979) Cytoprotection by Prostaglandins. Gastroenterology 77:761–767
Scheurer U, Schlegel JF, Kelly DG, Code CF (1981) Chronic bile exposure increases resistance of canine gastric mucosa to bile. Scand J Gastroenterol [Suppl] 67:205–210
Schumpelick V, Begemann F (1979) DGR und klinische Streßulkus-Gefährdung. In: Schumpelick H, Begemann F, Berndt W (Hrsg) Refluxkrankheit des Magens. Enke, Stuttgart, S 96–103
Stremple JF, Mori H, Lev R, Glass GBJ (1973) The stress ulcer Syndrome. In: (eds) Current problems in surgery year book medical. Publishers, Chicago, p. 33–36
Thjodleifsson B, Wormsley KG (1977) Back-diffusion — fact or fiction? Digestion 15:53–72
Whitfield PF, Hobsley M (1977) Failure to detect back-diffusion in human gastric aspirate. Gut 18:947
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Halter, F. (1982). Pathogenese. In: Siewert, J.R., Blum, A.L., Farthmann, E.H., Lankisch, P.G. (eds) Notfalltherapie. Interdisziplinäre Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68497-5_23
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