Skip to main content

Konservative Therapie

  • Conference paper
Notfalltherapie

Part of the book series: Interdisziplinäre Gastroenterologie ((GASTROENTEROLOG))

Zusammenfassung

Oesophagusvaricen sind dauerhaft unter erhöhtem Binnendruck stehende und konsekutiv abnorm erweiterte Venen der Speiseröhre. Ihre Wandung ist durch eine Rarefizierung der Media mit sekundärem Ersatz durch Bindegewebe, eine Unterbrechung der Elastica interna als geschlossene Grenzlamelle und eine fibröse Verdickung der Intima gekennzeichnet [70].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Aronsen KF, Wetterlin S, Emås S, Vojtišek V, Mulder JL, Cort JH (1975) Die Wirkung von Triglycyl-Lysin-Vasopressin auf Kontrollpersonen und Patienten mit Blutungen des oberen Gastrointestinaltraktes. Klin Wochenschr 53:747–753

    Article  PubMed  CAS  Google Scholar 

  2. Barr JW, Lakin RC, Rösch J (1975) Similarity of arterial and intravenous Vasopressin on portal and systemic hemodynamics. Gastroenterology 69:13–19

    PubMed  CAS  Google Scholar 

  3. Bauer JJ, Kreel I, Kark AE (1974) The use of the Sengstaken-Blakemore tube for immediate control of bleeding esophageal varices. Ann Surg 179:273–277

    Article  PubMed  CAS  Google Scholar 

  4. Baum S, Nusbaum M (1971) The control of gastrointestinal hemorrhage by selective mesenteric arterial infusion of vasopressin. Radiology 98:497–505

    PubMed  CAS  Google Scholar 

  5. Beller BM, Trevino A, Urban E (1971) Pitressin induced myocardial injury and depression in a young woman. Am J Med 51:675–679

    Article  PubMed  CAS  Google Scholar 

  6. Berardi RS (1974) Vascular complications of superior mesenteric artery infusion with pitressin in treatment of bleeding esophageal varices. Am J Surg 127:757–761

    Article  PubMed  CAS  Google Scholar 

  7. Bertrand L, Michel H (1969) La sonde de Linton-Nachlas. Sa supériorité sur celle de Sengstaken-Blakemore pour le tamponnement des varices oeso-gastriques chez le cirrhotique. Arch Fr Mal Appar Dig 58:797–816

    CAS  Google Scholar 

  8. Bosch J, Kravetz D, Rodes J (1981) Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver:comparison with Vasopressin. Gastroenterology 80:518–525

    PubMed  CAS  Google Scholar 

  9. Boyce HW Jr (1962) Modification of the Senkstaken-Blakemore balloon tube. N Engl J Med 267:195–196

    Article  PubMed  Google Scholar 

  10. Brunswig D, Liehr H (1972) Die Behandlung der Ösophagusvarizenblutung mit der Linton-Nachlas-Sonde. Dtsch Med Wochenschr 97:502–507

    Article  PubMed  CAS  Google Scholar 

  11. Brunswig D, Spech HJ, Heine WD (1974) Komplikationen bei der Behandlung von Ösophagusvarizenblutungen mit Ballonsonden. Therapiewoche 24:4261–4264

    Google Scholar 

  12. Bützow GH, Ossenberg FW (1981) Hämodynamische Veränderungen bei Leberzirrhose. In:Eckert P, Liehr H (Hrsg) Akutes und chronisches Leberversagen. Thieme, Stuttgart New York, S 68–73

    Google Scholar 

  13. Burcharth F, Malmstrom J (1976) Experiences with the Linton-Nachlas and the Sengstaken-Blakemore tubes for bleeding esophageal varices. Surg Gynecol Obstet 142:529–531

    PubMed  CAS  Google Scholar 

  14. Chojkier M, Conn HO (1980) Esophageal tamponade in the treatment of bleeding varices. A decadal progress report. Dig Dis Sci 25:267–272

    Article  PubMed  CAS  Google Scholar 

  15. Chojkier M, Groszmann RJ, Atterbury CE et al. (1979) A controlled comparison of continuous intraarterial and intravenous infusion of Vasopressin in hemorrhage from esophageal varices. Gastroenterology 77:540–546

    PubMed  CAS  Google Scholar 

  16. Clanet J, Tournut R, Fourtanier G, Joncquiert F, Pascal JP (1978) Traitement par la pitressine des hémorragies par rupture de varices oesophagiennes chez le cirrhotique. Etüde contrôlée. Acta Gastroenterol Belg 41:539–543

    PubMed  CAS  Google Scholar 

  17. Conn HO (1958) Hazards attending the use of esophageal tamponade. N Engl J Med 259:701–707

    Article  PubMed  CAS  Google Scholar 

  18. Conn HO (1970) The prognosis and management of bleeding esophageal varices. Ann NY Acad Sci 170:345–357

    Article  Google Scholar 

  19. Conn HO (1974) The rational evaluation and management of portal hypertension. In:Schaffner F Sherlock S, Leevy CM (eds) The liver and its diseases. Thieme, Stuttgart, S 289–306

    Google Scholar 

  20. Conn HO, Simpson JA (1967) Excessive mortality associated with balloon tamponade of bleeding varices. A critical reappraisal. JAMA 202:587–591

    Article  PubMed  CAS  Google Scholar 

  21. Conn HO, Ramsby GR, Storer EH (1972) Selective intraarterial Vasopressin in the treatment of upper gastrointestinal hemorrhage. Gastroenterology 63:634–645

    PubMed  CAS  Google Scholar 

  22. Conn HO, Ramsby GR, Storer EH et al. (1975) Intraarterial Vasopressin in the treatment of upper gastrointestinal hemorrhage:a prospective controlled clinical trial. Gastroenterology 68:211–221

    PubMed  CAS  Google Scholar 

  23. Eckardt VF, Grace ND (1979) Gastroesophageal reflux and bleeding esophageal varices. Gastroenterology 76:39–42

    PubMed  CAS  Google Scholar 

  24. Felson B, Lessure AR (1964) “Downhill” varices of the esophagus. Dis Chest 46:740–746

    Article  PubMed  CAS  Google Scholar 

  25. Feruglio FS, Greco F, Cesano L, Indovina D, Sardi G, Chiandussi L (1964) Effect of drug infusion on systemic and splanchnic circulation. II. Octapressin infusion in normal and cirrhotic subjects. Clin Sci (Oxf) 26:493–498

    CAS  Google Scholar 

  26. Freedman AR, Kerr JC, Swan KG, Robson II RW (1978) Primate mesenteric blood flow. Effects of Vasopressin and its route of delivery. Gastroenterology 74:875–878

    PubMed  CAS  Google Scholar 

  27. Gallenkamp H, Liehr H (1981) Aspekte zur Therapie der Ösophagusvarizenblutung. Med Welt 32:393–397

    PubMed  CAS  Google Scholar 

  28. Gerstenberg E, Taenzer V, Bachmann D, Wöllgens P (1971) Downhill-Varizen:Ösophagusvarizen ohne portale Hypertension. Med Welt 22:1433–1436

    PubMed  CAS  Google Scholar 

  29. Getzen LC, Brink RR, Wolfman EF Jr (1978) Survival following infusion of pitressin into the superior mesenteric artery to control bleeding esophageal varices in cirrhotic patients. Ann Surg 187:337–342

    Article  PubMed  CAS  Google Scholar 

  30. Greenwald RA, Rheingold OJ, Chiprut RO, Rogers AI (1978) Local gangrene:a complication of peripheral pitressin therapy for bleeding esophageal varices. Gastroenterology 74:744–746

    PubMed  CAS  Google Scholar 

  31. Heene DL (1979) Hämostasestörungen bei Lebererkrankungen. In:Kühn HA, Wernze H (Hrsg) Klinische Hepatologie. Thieme, Stuttgart, S 3105–3119

    Google Scholar 

  32. Heil T, Mattes P, Loeprecht H (1979) Der gastrooesophageale Reflux — auslösender Faktor der Oesophagusvarizenblutung? Chirurg 50:640–642

    PubMed  CAS  Google Scholar 

  33. Hermann RE, Traul D (1970) Experience with the Sengstaken-Blakemore tube for bleeding esophageal varices. Surg Gynecol Obstet 130:879–885

    PubMed  CAS  Google Scholar 

  34. Hey D, Ditter H, Berndt D, Neuhof H (1973) Die Beeinflussung der kollageninduzierten Plättchenaggregation durch verschiedene Plasmaersatzmittel. Med Welt 24:1167–1170

    PubMed  CAS  Google Scholar 

  35. Joelsson B, Börjesson B, Carlsson C, Gustafson I (1981) Acute treatment of bleeding oesophageal varices. A retrospective study of 88 patients. Scand J Gastroenterol 16:81–85

    PubMed  CAS  Google Scholar 

  36. Johansen TS, Baden H (1973) Re-appraisal of the Sengstaken-Blakemore balloon tamponade for bleeding esophageal varices; results in 91 patients. Scand J Gastroenterol 8:181–183

    PubMed  CAS  Google Scholar 

  37. Johnson WC, Widrich WC, Ansell JE, Robbins AH, Nabseth DC (1977) Control of bleeding varices by vasopressin:a prospektive randomized study. Ann Surg 186:369–376

    Article  PubMed  CAS  Google Scholar 

  38. Kehne HJ, Hughes FA, Gompertz ML (1956) The use of surgical pituitrin in the control of esophageal varix bleeding. An experimental study and report of two cases. Surgery 39:917–925

    PubMed  CAS  Google Scholar 

  39. Lagemann K (1973) Obere Oesophagusvarizen bei Struma. Fortschr Röntgenstr 118:440–445

    Article  CAS  Google Scholar 

  40. Lebrec D, DeFleury P, Rueff B, Nahum H, Benhamou JP (1980) Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis. Gastroenterology 79:1139–1144

    PubMed  CAS  Google Scholar 

  41. Liebowitz HR (1961) Pathogenesis of esophageal varix rupture. JAMA 175:874–879

    PubMed  CAS  Google Scholar 

  42. Liehr H, Doht F, Brugger E, Feldmann K, Brunswig D (1981) Zur Pathophysiologie von Antithrombin III und alpha-2-Makroglobulin bei Leberzirrhose. Verh Dtsch Ges Inn Med 87:946–949

    Google Scholar 

  43. Linton RR (1953) The emergency and definitive treatment of bleeding esophageal varices. Gastroenterology 24:1–9

    PubMed  CAS  Google Scholar 

  44. Merigan TC Jr, Plotkin GR, Davidson CS (1962) Effect of intravenously administered posterior pituitary extract on hemorrhage from bleeding esophageal varices. A controlled evaluation. N Engl J Med 266:134–135

    Article  PubMed  Google Scholar 

  45. Mitchell KJ, MacDougall BRD, Silk DBA, Williams R (1978) New view on treatment of portal hypertension. Acta Gastroenterol Belg 41:479–490

    PubMed  CAS  Google Scholar 

  46. Mitchell K, Silk DBA, Williams R (1980) Prospective comparison of two Sengstaken tubes in the management of patients with variceal haemorrhage. Gut 21:570–573

    Article  PubMed  CAS  Google Scholar 

  47. Murray-Lyon IM, Pugh RNH, Nunnerley HB, Laws JW, Dawson JL, Williams R (1973) Treatment of bleeding oesophageal varices by infusion of Vasopressin into the superior mesenteric artery. Gut 14:59–63

    Article  PubMed  CAS  Google Scholar 

  48. Nachlas MM (1955) A new triple lumen tube for the diagnosis and treatment of upper gastrointestinal hemorrhage. N Engl J Med 252:720–721

    Article  PubMed  CAS  Google Scholar 

  49. Novis BH, Duys P, Barbezat GO, Ciain J, Bank S, Terblanche J (1976) Fibreoptic endoscopy and the use of the Sengstaken tube in acute gastrointestinal haemorrhage in patients with portal hypertension and varices. Gut 17:258–263

    Article  PubMed  CAS  Google Scholar 

  50. Nusbaum M, Younis MT, Baum S, Blakemore WS (1974) Control of portal hypertension. Selective mesenteric arterial infusion of Vasopressin. Arch Surg 108:342–347

    PubMed  CAS  Google Scholar 

  51. Orloff NJ, Thomas HS (1963) Pathogenesis of esophageal varix rupture. Arch Surg 87:301–306

    PubMed  CAS  Google Scholar 

  52. Palmer ED (1970) Endoscopic contributions to the understanding of portal hypertension. Ann NY Acad Sci 170:164–176

    Article  Google Scholar 

  53. Pitcher JL (1971) Safety and effectiveness of the modified Sengstaken-Blakemore tube:a prospective study. Gastroenterology 61:291–298

    PubMed  CAS  Google Scholar 

  54. Raptis S, Zoupas C (1979) Somatostatin not helpful in bleeding esophageal varices. N Engl J Med 300:736–737

    PubMed  CAS  Google Scholar 

  55. Read AE, Dawson AM, Kerr DNS, Turner MD, Sherlock S (1960) Bleeding oesophageal varices treated by oesophageal compression tube. Br Med J 7:227–231

    Article  Google Scholar 

  56. Renert WA, Button KF, Fuld SL, Casarella WJ (1972) Mesenteric venous thrombosis and small-bowel infarction following infusion of Vasopressin into the superior mesenteric artery. Radiology 102:299–302

    PubMed  CAS  Google Scholar 

  57. Reynolds TB, Ito S, Iwatsuki S (1970) Measurement of portal pressure and its clinical application. Am J Med 49:649–657

    Article  PubMed  CAS  Google Scholar 

  58. Schröder R, Vang J (1973) Zur Therapie der schweren Ösophagusvarizenblutung. Schweiz Med Wochenschr 103:1081–1086

    PubMed  Google Scholar 

  59. Sengstaken RW, Blakemore AH (1950) Balloon tamponade for the control of hemorrhage from esophageal varices. Ann Surg 131:781–789

    Article  PubMed  CAS  Google Scholar 

  60. Sonnenberg GE, Keller U, Perruchoud A, Burckhardt D, Gyr K (1981) Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects. Gastroenterology 80:526–532

    PubMed  CAS  Google Scholar 

  61. Spech HJ, Wördehoff D (1982) Klassifizierung von Ösophagusvarizen — endoskopische und klinische Aspekte. Leber Magen Darm 12. Im Druck

    Google Scholar 

  62. Stelzner F, Lierse W (1968) Der angiomuskuläre Dehn Verschluß der terminalen Speiseröhre. Langenbecks Arch Chir 321:35–64

    Article  PubMed  CAS  Google Scholar 

  63. Terés J, Cecilia A, Bordas JM, Rimola A, Bru C, Rodés J (1978) Esophageal tamponade for bleeding varices. Controlled trial between the Sengstaken-Blakemore tube and the Linton-Nachlas tube. Gastroenterology 75:566–569

    PubMed  Google Scholar 

  64. Thulin L, Tyden G, Samnegård H, Muhrbeck O, Efendić S (1979) Treatment of bleeding oesophageal varices with somatostatin. Acta Chir Scand 145:395–398

    PubMed  CAS  Google Scholar 

  65. Tydén G, Samnegård H, Thulin L, Friman L, Efendić S (1978) Treatment of bleeding esophageal varices with somatostatin. N Engl J Med 299:1466–1467

    Article  PubMed  Google Scholar 

  66. Tydén G, Samnegård H, Thulin L, Efendić S (1979) Somatostatin and bleeding varices. N Engl J Med 301:46

    PubMed  Google Scholar 

  67. Varela PM, Cosme A, Muro J, Cano JM, Vazquez O (1973) Utilidad de la sonda-balón de Sengstaken-Blakemore. Estudio prospectivo. Rev Esp Enferm Apar Dig 39:283–298

    Google Scholar 

  68. Wehinger H (1967) Zur Beeinflussung der Blutgerinnung durch niedermolekulares Dextran (Rheo-Macrodex). Klin Wochenschr 45:1031–1035

    Article  PubMed  CAS  Google Scholar 

  69. Westaby S, Wilkinson SP, Warren R, Williams R (1978) Spleen size and portal hypertension in cirrhosis. Digestion 17:63–68

    Article  PubMed  CAS  Google Scholar 

  70. Zeitlhofer J (1970) Über die Oesophagusvarizenblutung. Wien Z Inn Med 51:90–92

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Spech, H.J., Liehr, H. (1982). Konservative Therapie. In: Siewert, J.R., Blum, A.L., Farthmann, E.H., Lankisch, P.G. (eds) Notfalltherapie. Interdisziplinäre Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68497-5_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68497-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68498-2

  • Online ISBN: 978-3-642-68497-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics