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Ulcus-Therapie pp 113-122 | Cite as

Symptomatik des peptischen Ulcus

  • S. A. Müller-Lissner
Conference paper
Part of the Interdisziplinäre Gastroenterologie book series (GASTROENTEROLOG)

Zusammenfassung

„Die Symptome des Duodenalulcus sind eindeutig und nicht leicht zu mißdeuten. Unmittelbar nach einer Mahlzeit verspürt der Patient Erleichterung; wenn zuvor Schmerzen oder Unwohlsein bestanden, so bessert die Mahlzeit diese und beseitigt sie für eine Weile völlig… Viele Patienten berichten spontan, daß die Schmerzen beginnen,,sobald sie anfangen, hungrig zu werden‘, und ich schlug deshalb in einer meiner früheren Publikationen den Begriff,Hungerschmerz‘zur Beschreibung dieses Symptoms vor. Es ist sehr charakteristisch für den Schmerz, daß er den Patienten nachts weckt; und als Zeit des Erwachens wird regelmäßig 2 Uhr angegeben…

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Literatur

  1. 1.
    Bockus, H.L.: Symptomatic and physical diagnosis of uncomplicated gastric and duodenal ulcer. In: Peptic ulcer. Sandweiss, D.J. (ed.), pp. 199–208. Philadelphia, London: Saunders 1951Google Scholar
  2. 2.
    Bonney, G.L.W., Pickering, G.W.: Observations on the mechanism of pain in ulcer of the stomach and duodenum. Part I - The nature of the stimulus. Clin. Sci. 6, 63–90 (1946)Google Scholar
  3. 3.
    Bonney, G.L.W., Pickering, G.W.: Observations on the mechanism of pain in ulcer of the stomach and duodenum. Part II—The location of the pain nerve endings. Clin. Sci. 6, 91–111 (1946)PubMedGoogle Scholar
  4. 4.
    Chinn, A.B., Weckesser, E.C.: Acute hemorrhage from peptic ulceration: An analysis of 322 cases. Ann. Intern. Med. 34, 339–351 (1951)PubMedGoogle Scholar
  5. 5.
    Clarke, M., Halil, T., Salmon, N.: Peptic ulceration in man. Epidemiology and medical care. Br. J. Prev. Soc. Med. 30, 115–122 (1976)PubMedGoogle Scholar
  6. 6.
    Collen, MJ., Hanan, M.R., Mäher, J.A., Rent, M., Stubrin, S.E., Arguello, J.F., Gardner, L.: Cimetidine vs placebo in duodenal ulcer therapy. Six-week controlled double- blind investigation without any antacid therapy. Dig. Dis. Sei. 25, 744–749 (1980)CrossRefGoogle Scholar
  7. 7.
    Davies, W.A., Reed, P.I.: Controlled trial of duogastrone in duodenal ulcer. Gut 18, 78–83 (1977)PubMedCrossRefGoogle Scholar
  8. 8.
    Demling, L., Rösch, W.: Peptisches Ulcus. In: Handbuch der inneren Medizin, 5. Aufl. Bd. 3/2: Magen. Demling, L. (Hrsg.), pp. 659–772. Berlin, Heidelberg, New York: Springer 1974Google Scholar
  9. 9.
    Dunn, J.P., Etter, L.E.: Inadequacy of the medical history in the diagnosis of duodenal ulcer. N. Engl. J. Med. 266, 68–72 (1962)PubMedCrossRefGoogle Scholar
  10. 10.
    Earlam, R.: A computerized questionnaire analysis of duodenal ulcer symptoms. Gastroenterology 77, 314–317 (1976)Google Scholar
  11. 11.
    Edwards, F.C., Coghill, N.F.: Clinical manifestations in patients with chronic atrophic gastritis, gastric ulcer, and duodenal ulcer. Q. J. Med. 37, 337–360 (1968)PubMedGoogle Scholar
  12. 12.
    Frost, F., Rahbek, I., Rune, S.J., et al.: Cimetidine in patients with gastric ulcer. Br. Med. J. 2, 795–799 (1977)PubMedCrossRefGoogle Scholar
  13. 13.
    Frühmorgen, P., Jenny, S., Classen, M., Bauerle, H., Koch, H.: Anamnese bei Ulkus und Narben im Bulbus duodeni. Dtsch. Med. Wochenschr. 97, 188–193 (1972)PubMedCrossRefGoogle Scholar
  14. 14.
    Gäumann, N., Jost, L., Müller-Lissner, S.A., Schmid, P., Jenny, S., Blum, A.L.: Refluxoesophagitis und Ulcuskrankheit—Koinzidenz? Schweiz. Med. Wochenschr. (im Druck)Google Scholar
  15. 15.
    Gibbs, J.O.: A study of 219 cases of peptic ulcer in series of 2301 consecutive necropsies. Q. Bull. Northwest. Univ. Med. Sch. 20, 328–338 (1946)PubMedGoogle Scholar
  16. 16.
    Hafter, E.: Praktische Gastroenterologie, 6. Aufl. Stuttgart: Thieme 1978Google Scholar
  17. 17.
    Hajdu, I., Balogh, I., Forgacs, S.: Gastroduodenales Altersulkus. Klinik und Röntgenbild. M.M.W. 12, 532–537 (1972)Google Scholar
  18. 18.
    Hess, H., Würsch, T.G., Killer-Walser, R., et al.: How often does peptic ulcer produce “typical“ ulcer symptoms? Acta Hepatogastroenterol. (Stuttg.) 27, 57–61 (1980)Google Scholar
  19. 19.
    Hollander, D., Harland, J.: Antacids vs placebos in peptic ulcer therapy. A controlled double-blind investigation. J.A.M.A. 226, 1181–1185 (1973)PubMedCrossRefGoogle Scholar
  20. 20.
    Horrocks, J.C., Dombai, F.T. de: Clinical presentation of patients presenting with “dyspepsia“. Detailed symptomatic study of 360 patients. Gut 79, 19–26 (1978)CrossRefGoogle Scholar
  21. 21.
    Ippoliti, A.F., Sturdevant, R.A.L., Isenberg, J.I., et al.: Cimetidine versus intensive antacid therapy for duodenal ulcer. Gastroenterology 74, 393–395 (1978)PubMedGoogle Scholar
  22. 22.
    Ivy, A.C., Grossman, M.I., Bachrach, W.H.: Peptic ulcer. Philadelphia, Toronto: Blakiston 1950Google Scholar
  23. 23.
    James, O., Kenefick, J.S.: Pain in peptic ulcer. Proc. R. Soc. Med. 68, 286 - 287 (1975)PubMedGoogle Scholar
  24. 24.
    Kasich, A.M., Fein, H.D., Boleman, A.P.: Pain in peptic ulcer. Experimental observations on the factors involved in the pain mechanism. Am. J. Med. Sci. 241, 111–115 (1961)CrossRefGoogle Scholar
  25. 25.
    Krag, E.: The pseudo-ulcer syndrome. A clinical, radiographic and statistical follow-up study in patients with ulcer symptoms but no demonstrable ulcer in the stomach or duodenum. Dan. Med. Bull. 16, 6–9 (1969)PubMedGoogle Scholar
  26. 26.
    Kratzsch, K.-H., Fürstenau, M., Zimmermann, S.: Ulkusanamnese und gastoduodeno- skopischer Befund—ein Beitrag zur Symptomatologie des gastroduodenalen Ulcus. Z. Ges. Inn. Med. 34, 530–534 (1979)PubMedGoogle Scholar
  27. 27.
    Lam, S.K., Lam, K.C., Lai, C.L., Yeung, C.K., Yam, L.Y.C., Wong, W.S.: Treatment of duodenal ulcer with antacid and sulpiride. A double-blind controlled study. Gastroenterology 76, 315–322 (1979)PubMedGoogle Scholar
  28. 28.
    Lawson, H.H., Rovelstad, R.A.: Continuous recording of pH in the duodenal bulb after food and alkali. Gut 10, 215–218 (1969)PubMedCrossRefGoogle Scholar
  29. 29.
    Marks, I.N., Wright, J.P., Denyer, M., Garisch, J.A.M., Lücke, W.: Comparison of sucralfate with Cimetidine in the short-term treatment of chronic peptic ulcers. S. Afr. Med. J. 57, 567–573 (1980)PubMedGoogle Scholar
  30. 30.
    McCray, R.S., Ferris, E.J., Herskovic, T., Winawer, S.J., Shapiro, J.H., Zamchek, M.N.: Clinical differences between gastric ulcers with and without duodenal deformity. Ann. Surg. 168, 821–823 (1968)PubMedCrossRefGoogle Scholar
  31. 31.
    Möllmann, K.-M., Bonnevie, O., Gutbrand-Höyer, E., Wulff, H.R.: A diagnostic study of patients with upper abdominal pain. Scand. J. Gastroenterol. 10, 805–809 (1975)PubMedGoogle Scholar
  32. 32.
    Moshal, M.G.: The treatment of duodenal ulcers with TDB: A duodenoscopic double- blind cross-over investigation. Postgrad. Med. J. [Suppl. 5] 51, 36–40 (1975)PubMedGoogle Scholar
  33. 33.
    Moshal, M.G., Spitaels, J.M., Khan, F.: Sucralfate in the treatment of duodenal ulcers. S. Afr. Med. J. 57, 742–744 (1980)PubMedGoogle Scholar
  34. 34.
    Moynihan, B.G.A.: On duodenal ulcer: With notes of 52 operations. Lancet1905 I,340–346Google Scholar
  35. 35.
    Moynihan, B.G.A.: Duodenal ulcer, pp. 101–121. Philadelphia, London: Saunders 1910Google Scholar
  36. 36.
    Patterson, T.L., Sandweiss, D.J.: The relationship between gastroduodenal motility phases and symptoms associated with duodenal ulcer in the human. Am. J. Dig. Dis. 9, 375–383 (1942)CrossRefGoogle Scholar
  37. 37.
    Rhodes, J., Apsimon, H.T., Lawrie, J.H.: pH of the contents of the duodenal bulb in relation to duodenal ulcer. Gut 7, 502–508 (1966)PubMedCrossRefGoogle Scholar
  38. 38.
    Rinaldo, J.A., Scheinok, P., Rupe, C.E.: Symptom diagnosis. A mathematical analysis of epigastric pain. Ann. Intern. Med. 59, 145–154 (1963)PubMedGoogle Scholar
  39. 39.
    Ruffin, J.M., Baylin, G.J., Legerton, C.W., Texter, E.C.: Mechanism of pain in peptic ulcer. Gastroenterology 23, 252–269 (1953)PubMedGoogle Scholar
  40. 40.
    Rune, S.J., Zachariassen, A.: Acute relief of epigastric pain by antacids in duodenal ulcer patients. Scand. J. Gastroenterol. [Suppl.58] 14, 41–53 (1980)Google Scholar
  41. 41.
    Sheppard, M.C., Holmes, G.K.T., Cockel, R.: Clinical picture of peptic ulceration diagnosed endoscopically. Gut 18, 524–530 (1977)PubMedCrossRefGoogle Scholar
  42. 42.
    Smith, V.M., Feldman, M.: Silent peptic ulcer: A clinical and pathologic study. Gastroenterology 38, 978–979 (1960)Google Scholar
  43. 43.
    Sonnenberg, A., Kiene, K. Weber, K.B., Pelloni, S., Peter, P., Wienbeck, M., Strohmeyer, G., Blum, A.L.: Rezidivprophylaxe des Ulcus duodeni mit Cimetidin. Dtsch. Med. Wochenschr. 104, 725–730 (1979)PubMedCrossRefGoogle Scholar
  44. 44.
    Sturdevant, R.A.L., Isenberg, J.I., Secrist, D., Ansfield, J.: Antacid and placebo produced similar pain relief in duodenal ulcer patients. Gastroenterology 72, 1–5 (1977)PubMedGoogle Scholar
  45. 45.
    Weithofer, G., Langbein, G., Lübke, H., Bloch, R.: Zur Bedeutung der Magensäure für den Ulkusschmerz. Z. Gastroenterol. 19, 237–241 (1981)PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • S. A. Müller-Lissner

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