Abstract
Myogenic activity, contractions of the walls, and transit of contents represent the main aspects of motor activity in the alimentary canal. Myoelectric properties of the muscle layers regulate contractions of the walls. Wall contractions cause variations in the intraluminal pressure and thus pressure gradients, which may either stimulate or inhibit the transit of the contents. Knowledge of these motor aspects is due to, and, at the same time limited by, a particular technique; these limitations are even more evident in human investigations.
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References
Adler HF, Atkinson AJ, Ivy AC (1941) A study of the motility of the human colon: an explanation of dysynergia of the colon, or of the “unstable colon”. Am J Dig Dis 8:197–202.
Akkermans LMA, Jacobs F, Hong-Yoe O (1979) A non-invasive method to quantify antral contractile activity in man and dog. Abstracts 7 th International Symposium on Gastrointestinal Motility, Iowa City, University of Iowa, Iowa City, p 45.
Alvarez WC (1929) Physiologic studies on the motor activities of the stomach and bowel of man. Am J Physiol 88:650–662.
Alvarez WC, Freedlander BL (1924) The rate of progress of food residues through the large bowel. JAMA 83:576–580.
Arhan P, Faverdin C, Persoz B, Devroede G, Dubois F, Dornic C, Pellerin D (1976) Relationship between viscoelastic properties of the rectum and anal pressure in man. J Appl Physiol 41:677–682.
Arndorfer RC, Stef JJ, Dodds WJ, Linchan JH, Hogan WJ (1977) Improved infusion system for intraluminal esphageal manometry. Gastroenterology 73:23–27.
Atkinson M, Edwards DAW, Honour AJ, Rowlands EN (1957) Comparison of cardiac and pyloric sphincters. A manometric study. Lancet 2:918–922.
Barany F, Jacobson B (1964) Endoradiosonde study of propulsion and pressure activity induced by test meals, prostigmine, and diphenoxylate in the small intestine. Gut 5:90–95.
Barbaro V, Daniele Sargentini A, Frank M, Macellari V, Neroni M (1971) Use of a piezo-transistor for a pressure-sensitive radiotelemetering capsule. Rend Gastroenterol 3:34–37.
Bass P, Wiley JN (1972) Contractile force transducers for recording muscle activity in un-asthesized animals. J Appl Physiol 32:567–570.
Benmair Y, Dreyfuss F, Fishel B, Frei EH, Gilat T (1977 a) Study of gastric emptying using a ferromagnetic tracer. Gastroenterology 73:1041–1045.
Benmair Y, Fishel B, Frei EH, Gilat T (1977 b) Evaluation of a magnetic method for the measurement of small intestinal transit time. Am J Gastroenterol 68:470–475.
Biancani P, Zabinski MP, Behar J (1975) Pressure, tension, and forces of closure at the human lower esophageal sphincter and esophagus. J Clin Invest 56:476–483.
Bond JH, Levitt MD (1975) Investigation of small bowel transit time in man utilising pulmonary hydrogen (H2) measurement. J Lab Clin Med 85:546–555
Borgström S, Arborelius M Jr (1971) A technique for studying propulsion and the displacement of contents in the duodenum and proximal jejunum. Rend Gastroenterol 3:174–177.
Botha GSM, Astley R, Carre IJ (1957) A combined cineradiographic and manometric study of the gastro-esophageal junction. Lancet 1:659–662.
Brown BSJ (1965) Defecography or anorectal studies in children including cinefluoro-graphic observations. J Assoc Radiol 16:66–76.
Burnett FL (1923) The intestinal rate and form of the feces. Am J Roentgenol 10:599–604.
Cassano CC, Amoruso M, Arullani P, Badalamenti G (1967) Ricerche sui tempi di transito gastrointestinal totali parziali. Arch Ital Mal Appar Dig 34:290–293.
Chapman WP, Palazzo WL (1949) Multiple-balloon-kymograph recording of intestinal mo-tility in man with observations on the correlation of the tracing patterns with barium movements. J Clin Invest 28:1517–1525.
Chauve A, Devroede G, Bastin E (1976) Intraluminal pressures during perfusion of the human colon in situ. Gastroenterology 70:336–340.
Cohen S, Harris LD (1970) Lower esophageal sphincter pressure as an index of lower esophageal sphincter strength. Gastroenterology 58:157–162.
Cohen BR, Wolf BS (1968) Cineradiographic and intraluminal pressure correlations in the pharynx and esophagus. In: Code CF (ed) Alimentary canal. American Physiological Society, Washington, DC (Handbook of physiology, vol IV, sect 6, pp 1841–1860).
Connell AM, Rowlands EN (1960) Wireless telemetering from the digestive tract. Gut 1:266–272.
Cooper H, Levitan R, Fordtran JS, Ingelfmger FJ (1976) A method of studying absorption of water and solute from the human small intestine. Gastroenterology 50:1–7.
Corazziari E, Dani S, Pozzessere C, Anzini F, Torsoli A (1975) Colonic segmentai transit times in non-organic constipation. Rend Gastroenterol 7:67–69.
Cummings JH, Wiggins HS (1976) Transit through the gut measured by analysis of a single stool. Gut 17:219–223.
Delin NA, Axelsson B, Johansson C, Poppen B (1978) Comparison of gamma-camera and withdrawal method for the measurement of gastric emptying. Scand J Gastroenterol 13:867–872.
Deller DJ, Wangel AG (1965) Intestinal motility in man. I. A study combining the use of intraluminal pressure recording and cineradiography. Gastroenterology 48:45–57.
Dent J (1976) A new technique for continuous sphincter pressure measurement. Gastroenterology 71:263–267.
De Salamanca FE Jr (1949) Estudio de fisiologiá gåstrica en el perro. Trab Inst Nac Cienc Med 12:2–64.
Dodds WJ (1976) Instrumentation and methods for intraluminal esophageal manometry. Arch Intern Med 136:515–523.
Dodds WJ (1978) Efficient manometric techniques for accurate regional measurement of esophageal body motor activity. Am J Gastroenterol 70:21–24.
Dodds WJ, Stewart ET, Hogan WJ, Stef JJ, Arndorfer RC (1974) Effect of esophageal movement on intraluminal esophageal pressure recording. Gastroenterology 67:592–600.
Dodds WJ, Hogan WJ, Stef JJ, Lydon SB, Arndorfer RC (1975) A rapid pull-through technique for measuring lower esophageal sphincter pressure. Gastroenterology 68:437–443.
Donaldson RM Jr, Barreras RF (1966) Intestinal absorption of trace quantities of chromium. J Lab Clin Med 68:484–493.
Ehrenreich M (1912) Über die kontinuierliche Untersuchung des Verdauungsablaufs mittels der Magenverweilsonde. Z Klin Med 75:231–252.
Engelmann TW, Van Brakel G (1871) Über die peristaltische Bewegung, insbesondere des Darms. Arch Physiol 4:33–50.
Farrar JT, Bernstein JS (1958) Recording of intraluminal gastrointestinal pressures by a re-diotelemetering capsule. Gastroenterology 35:603–612.
Farrar JT, Zworkin VR, Baum J (1957) Pressure-sensitive telemetering capsules for study of gastrointestinal motility. Science 162:975–976.
Fisher RS, Malmud LS, Roberts CS, Lobis IF (1976) Gastroesophageal (GE) scintiscanning to detect and quantitate GE reflux. Gastroenterology 70:301–308.
Friedman G, Wolf BS, Waye JD, Janowitz HD (1965) Correlation of cineradiográphic and intraluminal pressure changes in the human duodenum: an analysis of the functional significance of monophasic wave. Gastroenterology 49:37–49.
Gaston EA (1948) The physiology of fecal continence. Surg Gynecol Obstet 87:280–290.
Gebauer A, Lissner J, Schott O (1967) Roentgen television. Grune & Stratton, New York London.
George JD (1968) New clinical method for measuring the rate of gastric emptying: the double sampling test method. Gut 9:237–242.
Gianturco C (1934) Some mechanical factors of gastric physiology, study I. Am J Roent-genol Radium Ther Nucl Med 31:735–750.
Hancock BD (1976) Measurement of anal pressure and motility. Gut 17:645–651.
Hansky YJ, Connell AM (1962) Measurement of gastrointestinal transit using radioactive chromium. Gut 3:187–188.
Harris LD, Pope CE II (1964) “Squeeze” vs. resistance, an evaluation of the mechanism of sphincter competence. J Clin Invest 43:2272–2278.
Harris LD, Winans CS, Pope CE II (1966) Determination of yield pressures; a method for measuring anal sphincter competence. Gastroenterology 50:754–760.
Harvey RF, MacKie DB, Brown NJG, Keeling DH (1970) Measurement of gastric emptying time with a gamma camera. Lancet 1:16–18.
Hay DJ, Goodall RJ, Temple JG (1979) The reproducibility of the station pullthrough technique for measuring lower oesophageal sphincter pressure. Br J Surg 66:93–97.
Heading RC, Tothill P, Laidlaw AJ, Shearman DJC (1971) An evaluation of 131indium DTPA chelate in the measurement of gastric emptying by scintiscanning. Gut 12:611–615.
Heading RC, Tothill P, McLoughlin GP, Shearman DJC (1976) Gastric emptying rate measurement in man. A double isotope scanning technique for simultaneous study of liquid and solid components of a meal. Gastroenterology 71:45–50.
Hendee WR (1970) Medical radiation physics. Year Book Medical Publisher, Chicago.
Hightower NC (1968) Motor action fo the small bowel. In: Code CF (ed) Alimentary canal. American Physiological Society, Washington, DC (Handbook of physiology, vol IV, sect 6, pp 2001–2024).
Hinton JM, Lennard-Jones JE, Young AW (1969) A new method for studying gut transit time using radioopaque markers. Gut 10:842–847.
Hollander F, Penner A (1939) History and development of gastric analysis procedures. Am J Dig Dis 5:22–25, 739-743, 786-791.
Hollis JB, Castell DO (1972) Amplitude of esophageal peristalsis as determined by rapid infusion. Gastroenterology 63:417–422.
Houckgeest JP, Van Braam (1872) Untersuchungen über Peristaltic des Magens und Darmkanals. Arch Ges Physiol 6:266–302.
Hunt JN (1974) A modification to the method of George for studying gastric emptying. Gut 15:812–813.
Hunt JN, Spurrell WR (1951) The pattern of emptying of the human stomach. J Physiol (Lond) 113:157–168.
Hurst AF (1919) Constipation and allied disorders, 2nd edn. Frowde, London.
Ingelfinger FJ, Abbott WD (1940) Intubation studies of the small intestine. XX. The diagnostic significance of motor disturbance. Am J Dig Dis 7:468–474.
Irhe T (1974) Studies on anal function in continent and incontinent patients. Scand J Gas-troenterol [Suppl 25] 9:1–64.
Jacoby HI, Bass P, Bennett DR (1963) In vivo extraluminal contractile force transducer for gastrointestinal muscle. J Appl Physiol 18:658–665.
Jahnberg T, Abrahmsson H, Jansson G, Martinson J (1977) Gastric relaxatory response to feeding before and after vagotomy. Scand J Gastroenterol 12:225–228.
Johansson C, Legerlof HO, Ekelund K, Kulsdom N, Larsson I, Nylond B (1972) Determination of gastric secretion and evacuation, biliary and pancreatic secretion, intestinal absorption, intestinal transit time and flow of water in man. Scand J Gastroenterol 7:489–499.
Kaye MD, Showalter JP (1971) Manometric configuration of the lower esophageal sphincter in normal human subjects. Gastroenterology 61:213–223.
Kaye MD, Showalter JP (1974) Measurement of pressure in the lower esophageal sphincter. The influence of catheter diameter. Am J Dig Dis 19:860–863.
Kaye MD, Showalter JP, Rock KC, Johnson E (1973) A circumferentially-sensitive miniature transducer for study of human esophageal motility. Gastroenterology 64:752.
Kazem I (1972) A new scintigraphic technique for the study of the esophagus. Am J Roent-genol Radium Ther Nucl Med 115:681–688.
Kelly MA (1974) The use of miniaturized mercury strain gauges to record gastric motility. In: Daniel EE (ed) Proceedings of the 5th International Symposium on Gastrointestinal Motility. Mitchell, Vancouver, pp 323–329.
Kirwan WD, Smith AN (1974) Gastrointestinal transit estimated by an isotope capsule. Scand J Gastroenterol 9:763–766.
Kronecker H, Meltzer SJ (1883) Der Schluckmechanismus, seine Erregung und seine Hemmung. Arch Ges Anat Physiol [Suppl] 7:328–332.
Lagerlof HO, Ekelund K, Johansson C (1972) A mathematical analysis of jejunal indicator concentrations used to calculate jejunal flow and mean transit time. Scand J Gastroenterol 7:379–389.
Lambert A, Eloy R, Grenier JF (1976) Transducer for recording electrical and mechanical chronic intestinal activity. J Appl Physiol 41:942–945.
Leube W (1883) Beiträge zur Diagnostik der Magenkrankheiten. Dtsch Arch Klin Med 33:1–21.
Lydon SB, Dodds WJ, Hogan WJ, Arndorfer RC (1975) Effect of manometric assembly diameter on intraluminal esophageal pressure. Am J Dig Dis 20:968–970
McKay RS, Jacobson B (1957) Endoradiosonde. Nature 179:1239–1240.
Malagelada JR, Longstreth GF, Summerskill WHJ, Go VLW (1976) Measurement of gastric functions during digestion of ordinary solid meals in man. Gastroenterology 70:203–210.
Manousos ON, Truelove SC, Lumsden K (1967) Transit times of food in patients with di-verticulosis or irritable colon syndrome and normal subjects. Br Med J 3:760–762.
Martelli H, Devroede G, Arhan P, Duguay C, Dornic C, Faverdin C (1978) Some parameters of large bowel motility in normal man. Gastroenterology 75:612–618
McKelvey STD (1970) Gastric incontinence and postvagotomy diarrhea. Br J Surg 57:741–747.
Meerof JC, Go VL, Phillips SF (1973) Gastric emptying of liquids in man. Quantification by duodenal recovery marker. Mayo Clin Proc 48:728–732.
Meyer JH, MacGregor IL, Gueller R, Martin P, Cavalieri R (1976) 99mTc tagged chicken liver as a marker of solid food in the human stomach. Am J Dig Dis 21:296–304.
Miller RE (1967) Barium sulphate as a contrast medium: In: Margulis AR, Burheune HJ (eds) Alimentary tract roentgenology. Mosby, Saint-Louis, pp 25–36.
Millhon WA, Hoffman DE, Jarvis P, Cross CJ, Millhon JS, Crites NA (1968) Preliminary report on Millhon-Crites intraesophageal motility probe. Am J Dig Dis 13:929–934.
Nauta J (1956) The closing mechanism between the esophagus and the stomach. Gastro-enterologia 86:219–241.
Nelsen TS, Angell JB (1979) Microminiature force transducers for chronic in vivo use. Abstracts 7 th International Symposium on Gastrointestinal Motility, Iowa City. University of Iowa, Iowa City, p 55.
Ostick DG, Green G, Howe K, Dymach IW, Cowley DJ (1975) A simple clinical method for measurement of gastric emptying of solid meals. Br J Surg 62:663.
Parks TG (1970) Motor responses in unresected and resected diverticular disease of the colon. Proc Roy Soc Med [Suppl] 63:3–6.
Pascaud XB, Genton JH, Bass P (1978) Gastroduodenal contractile activity in fed and fasted unrestrained rats. In: Duthie HL (ed) Gastrointestinal motility in health and disease. MTP, Lancaster England, pp 637–645.
Pope CE II (1967) A dynamic test of sphincter strength: its application to the esophageal sphincter. Gastroenterology 52:779–786.
Quigley JP, Brody DA (1952) A physiological and clinical consideration of the pressure developed in the digestive tract. Am J Med 13:73–81.
Ramorino MA, Colagrande C (1964) Intestinal motility: preliminary studies with telemetering capsules and synchronized fluorocinematography. Am J Dig Dis 9:64–71.
Ritchie JA (1968) Colonic motor activity and bowel function. Part I: Normal movement of contents. Gut 9:442–456.
Rosswick RP, Stedford RD, Brooke BN (1969) New methods of studying intestinal transit time. Gut 8:195–196.
Rothman MM, Katz AB (1964) Analysis of feces. Carmine or charcoal bowel motility test. In: Bockus HL (ed) Gastroenterology, 2nd ed, vol 2. Philadelphia, pp 695-696.
Schuster MM, Hendrix TR, Mendeloff AI (1963) The internal anal sphincter response. J Clin Invest 42:196–207.
Scopinaro F, Vignoni A, Gatti V, Pozzessere C, Anzini F, Corazziari E (1979) Role of scin-tigraphy in the detection of spontaneous gastroesophageal (GE) reflux. Eur J Nucl Med 4:140.
Staadas JO (1975 a) Intragastric pressure/volume relationship before and after proximal gastric vagotomy. Scand J Gastroenterol 10:129–134.
Staadas JO (1975 b) Intragastric pressure/volume relationship in the normal human stomach. Scand J Gastroenterol 10:135–140.
Stef JJ, Dodds WJ, Hogan WJ, Linehan JH (1974) Esophageal manometry component analysis of systems used to record intraluminal pressure. In: Daniel EE (ed) Proceedings of the 5 th International Symposium on Gastrointestinal Motility. Mitchell, Vancouver, pp 337–345.
Stef JJ, Dodds WJ, Hogan WJ, Linehan JJ, Stewart ET (1977) Intraluminal esophageal manometry: an analysis of variables affecting recording fidelity of peristaltic pressures. Gastroenterology 73:23–27.
Tasaka K, Farrar JT (1969) Mechanics of small intestinal muscle function in the dog. Am J Physiol 217:1224–1229.
Templeton RD, Lawson H (1931) Studies in the motor activity of the large intestine. Am J Physiol 96:667–676.
Tolin RD, Malmud LS, Menin R, Reilley J, Maxier PT, Fisher RS (1979 a) Detection and quantitation of enterogastric reflux following Billroth II surgery. J Nucl Med 19:739.
Tolin RD, Malmud LS, Reilley J, Fisher RS (1979 b) Esophageal scintigraphy to quantitate esophageal transit (quantitation of esophageal transit). Gastroenterology 76:1402–1408.
Torsoli A, Ramorino ML, Ammaturo MV, Capurso L, Arcangeli G, Paoluzi P (1971) Mass movement and intracolonic pressures. Am J Dig Dis 16:693–696.
Tothill P, McLoughlin GP, Heading RC (1978) Techniques and errors in scintigraphic measurement of gastric emptying. J Nucl Med 19:256–261.
Turano L (1957) Malattie non neoplastiche dell’esofago. In: Atti del Congr Ital Med Int, September 1957. Pozzi, Rome.
Waldeck F, Jennewein HM, Siewert R (1973) The continuous withdrawal method for the quantitative analysis of the lower esophageal sphincter (LES) in humans. Eur J Clin Invest 3:331–337.
Wallace RP, Ehrenfeld I, Cowett HP, Joliffe N, Shapiro LL, Sturtevant M (1938) Motility of the gastrointestinal tract. Am J Roentgenol 39:64–66.
Waller SL (1975) Differential measurements of small and large bowel transit times in constipation and diarrhea. A new approach. Gut 16:372–378.
Weisbrodt NW (1974) Application of extraluminal force transducers to motility. In: Daniel EE (ed) Proceedings of the 5 th International Symposium on Gastrointestinal Motility. Mitchell, Vancouver, pp 331–335.
Welch RW, Drake ST (1980) Normal lower esophageal sphincter pressure: a comparison of rapid vs. slow pull-through techniques. Gastroenterology 78:1446–1451.
Wheatley IC, Hardy KJ, Dent J (1977) Anal pressure studies in spinal patients. Gut 18:488–490.
Wilkinson R (1971) Polyethylene glycol 4000 as a continuously administered non-absorb-able fecal marker for metabolic balance studies in human subjects. Gut 12:654–660.
Winans CS (1972) The pharyngoesophageal closure mechanism: a manometric study. Gastroenterology 63:768–777.
Wingate DL, Sondberg RJ, Phillips SF (1972) A comparison of stable and 14C labelled polyethylene glycol or volume indicators in the human jejunum. Gut 3:812–815.
Wolf BS, Khilnani MT (1966) Progress in gastroenterological radiology. Gastroenterology 51:542–559.
Zapponi GA, Bausano G, Corazziari E, Pozzessere C, Anzini F, Torsoli A (1979) Progres-sione del contenuto attraverso l’intestino crasso in soggetti con tempo di transito normale. Ital J Gastroenterol [Suppl] 11:132.
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Corazziari, E. (1982). In Vivo Techniques for the Study of Gastrointestinal Motility. In: Bertaccini, G. (eds) Mediators and Drugs in Gastrointestinal Motility I. Handbook of Experimental Pharmacology, vol 59 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68437-1_7
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