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Dünndarm A pp 658–685Cite as

Diarrhöen

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Part of the book series: Handbuch der inneren Medizin ((INNEREN 3,volume 3 / 3 / A))

Zusammenfassung

Bereits unter physiologischen Bedingungen reguliert der obere Dünndarm wechselnd große und in Osmolarität sowie pH unterschiedlichste Flüssigkeitsvolumina: ca. 1 1 Sekret aus den Speicheldrüsen (Davenport 1966), das im Vergleich zur Körpertonizität osmotisch stark hypoton ist (Thaysen et al. 1954), ca. 2 1 Magensaft mit überwiegend sauren Valenzen (Davenport 1966), ca. 3 1 Sekret aus exokriner Pankreassekretion und biliärer Sekretion (Doubilet u. Fishman 1961) sowie die Sekretmenge, die von der Schleimhaut des oberen Dünndarms, speziell den Brunner-Drüsen als succus entericus produziert wird und mit ca. 1 1/die (Phillips 1972) kalkuliert werden kann. Hinzu kommen ca. 2 1 Flüssigkeit durch Nahrungsaufnahme, wobei hier Extreme bezüglich Volumen, Gesamtosmolarität, Elektrolyt- und Säure-Basen-Gehalt zu äquilibrieren sind. Berücksichtigt man weiter, daß die Nahrung selbst sowie insbesondere die Spaltprodukte der Kohlenhydrat- und Eiweißverdauung im Lumen des oberen Dünndarms als osmotisch aktive Substanzen zu kompensieren sind, so wird klar, welche Bedeutung dem oberen Dünndarm allein für die Aufrechterhaltung der Homöostase unter physiologischen Bedingungen zukommt.

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  1. R. Wanitschke
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Editor information

Editors and Affiliations

  1. Cattedra di Clinica Medica III, Università di Bologna, Via Massarenti, 9, I-Bologna, Italia

    F. Bazzoli

  2. I. Medizinische Abteilung, Marienkrankenhaus, Alfredstr. 9, D-2000, Hamburg 76, Deutschland

    R. Böhmer

  3. Medizinische Klinik II, Stadtkrankenhaus, Leimenstr. 20, D-6450, Hanau 1, Deutschland

    W. F. Caspary

  4. Abteilung Interne Strahlendiagnostik, Mannkopffstr. 1, D-3550, Marburg, Deutschland

    H. Dombrowski

  5. I. Medizinische Klinik und Poliklinik, Klinikum der Johannes Gutenberg-Universität, Lagenbeckstr. 1, D-6500, Mainz, Deutschland

    B. Eckhardt  & B. Lembcke  & 

  6. Medizinische Klinik und Poliklinik, Abteilung für Gastroenterologie und Stoffwechselkrankheiten, Kliniken der Universität, Humboldtallee 1, D-3400, Göttingen, Deutschland

    B. Elsenhans

  7. Abteilung für Allgemein- und Abdominalchirurgie, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, Deutschland

    A. Encke

  8. Gastrointestinal Unit, Western General Hospital, University of Edinburgh, Crewe Road, EH4 2XU, Edinburgh, Scotland, UK

    A. Ferguson

  9. Institut für Pharmakologie und Toxikologie, Medizinische Fakultät der Ludwig-Maximilians-Universität, Nußbaumstr. 26, D-8000, München 2, Deutschland

    W. Forth

  10. School of Medicine, Department of Medicine, Montefiore Hospital, University of Pittsburgh, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA

    H. Fromm

  11. I. Universitätsklinik für Gastroenterologie und Hepatologie, Lazarettgasse 14, A-1090, Wien, Österreich

    A. Gangl

  12. Medizinische Klinik und Poliklinik, Abteilung für Innere Medizin mit Schwerpunkt Gastroenterologie, Universitätsklinikum Steglitz, Hindenburgdamm 30, D-1000, Berlin 45, Deutschland

    S. Gutschmidt

  13. School of Medicine, Department of Anatomy, Case Western Reserve University, Cleveland, OH, 44106, USA

    U. Hopfer

  14. Health Science Center at Dallas, Southwestern Medical School, Department of Internal Medicine, The University of Texas, 5323 Harry Hines Boulevard, Dallas, TX, 75235, USA

    G. J. Kreijs  & R. Wanitschke  & 

  15. Abteilung Gastroenterologie und Stoffwechsel, Zentrum Innere Medizin der Universität, Robert-Koch-Str. 40, Göttingen, D-3400, Deutschland

    K.-H. Meyer zum Büschenfelde

  16. Institut für Klinische und Experimentelle, Nuklearmedizin der Universitätskliniken, Joseph-Stelzmann-Str. 9, Köln 41, D-5000, Deutschland

    G. Mödder

  17. Theoretische Medizin, Fachrichtung 3.4 - Pharmakologie-Toxikologie, Fachbereich 3 der Universität des Saarlandes, Homburg, D-6650, Deutschland

    G. Nell

  18. Pathologisches Institut, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, Hamburg 20, D-2000, Deutschland

    H. F. Otto

  19. 2. Medizinische Klinik und Poliklinik, Medizinische Einrichtungen der Universität, Moorenstr. 5, Düsseldorf 1, D-4000, Deutschland

    H. Peerenboom

  20. Institut für Ernährungswissenschaft der Justus-Liebig-Universität, Wilhelmstr. 20, Giessen, D-6300, Deutschland

    G. Rehner

  21. Innere Abteilung, Kreiskrankenhaus, Bunsenstr. 120, Böblingen, D-7030, Deutschland

    G. Rettenmaier

  22. Service de Chirurgie, Département de Chirurgie Expérimentale, Hôpital Cantonal Universitaire, Lausanne 11 CHUV, CH-1011, Schweiz

    J. W. L. Robinson

  23. Abteilung Klinische Chemie, Zentrallabor, Klinikum der Universität, Uferstr. 2a, Marburg, D-3550, Deutschland

    K. Rommel

  24. Medizinische Klinik mit Poliklinik der Universität, Krankenhausstr. 12, Erlangen, D-8520, Deutschland

    H. Ruppin

  25. Experimentelle Chirurgie der Allgemeinchirurgie der Universität, Hospitalstr. 40, Kiel 1, D-2300, Deutschland

    J. Seifert

  26. Froedtert Memorial Lutheran Hospital, Section of Gastroenterology, The Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI, 53226, USA

    K. H. Soergel

  27. Gastrointestinal Unit and Department of Medicine, Wolson Gastrointestinal Laboratories, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, Scotland, UK

    S. Strobel

  28. Zentrum der Kinderheilkunde, Abteilung Allgemeine Pädiatrie I, Sektion Kindergastroenterologie, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, Frankfurt 70, D-6000, Deutschland

    S. Strobel

  29. Fachbereich Medizin, Anatomisches Institut, Johannes Gutenberg-Universität, Saarstr. 19/21, Mainz, D-6500, Deutschland

    L. Vollrath

  30. II. Medizinische Klinik, Krankenhausstiftung Bamberg, Untere Sandstr. 32, Bamberg, D-8600, Deutschland

    H. J. Weis

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Wanitschke, R. (1983). Diarrhöen. In: Bazzoli, F., et al. Dünndarm A. Handbuch der inneren Medizin, vol 3 / 3 / A. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68415-9_28

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  • DOI: https://doi.org/10.1007/978-3-642-68415-9_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68416-6

  • Online ISBN: 978-3-642-68415-9

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