Dünndarm A pp 298-308 | Cite as

Resorption von Oxalsäure und intestinale Hyperoxalurie

  • W. F. Caspary
Part of the Handbuch der inneren Medizin book series (INNEREN, volume 3 / 3 / A)

Zusammenfassung

Primäre Störungen des Oxalatstoffwechsels sind sehr selten vorkommende Erkrankungen. Sie treten meist in der Kindheit oder Jugend auf und imponieren durch eine erhöhte Oxalatausscheidung im Urin unter Bildung von Oxalatkonkrementen in den ableitenden Harnwegen (Williams u. Smith 1978). Obwohl der Oxalatstein der häufigste Nierenstein ist, lassen sich in nur seltenen Fällen Störungen des Oxalatstoffwechsels finden. Eine Hyperoxalurie galt deshalb lange als eine medizinische Kuriosität. In den letzten Jahren ist jedoch klargeworden, daß eine Hyperoxalurie bei Patienten mit verschiedensten gastrointestinalen Erkrankungen sogar relativ häufig ist. Bei ca. 2,6–10% der Patienten mit entzündlichen Darmerkrankungen, jedoch nur bei 0,1% der Patienten, die normalerweise in ein Krankenhaus aufgenommen werden, treten Nierensteine auf (Deren et al. 1962; Gelzayd et al. 1968; Boyce et al. 1956; Grossman u. Nugent 1967; Maratka u. Nedbal 1964). Das Vorkommen von Nierensteinen war bedeutend häufiger bei Patienten, die wegen einer chronischen Darmerkrankung operiert worden waren (Tabelle 1) (Deren et al. 1962; Maratka u. Nedbal 1964).

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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

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  • W. F. Caspary

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