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Examination of Synovial Fluid

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Bone and Joint Disease

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 71))

Abstract

Aspiration of excess synovial fluid from a swollen joint is sometimes necessary in the treatment of joint disease. It is essential for the confirmation of the diagnosis whenever the effusion is suspected to be due to infection, crystal synovitis or haemarthrosis. Examination of synovial fluid is also sometimes helpful in the differential diagnosis of other forms of arthropathy.

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References

  • Albrecht M, Marinetti GV, Jacox RF, Vaughan JH (1965) A biochemical and electron microscopy study of rice bodies from rheumatoid patients. Arthritis Rheum 8: 1053–1063

    PubMed  CAS  Google Scholar 

  • Baldassare AR, Chang F, Zuckner J (1978) Markedly raised synovial fluid leucocyte counts not associated with infectious arthritis in children. Ann Rheum Dis 37: 404–409

    PubMed  CAS  Google Scholar 

  • Barker SA, Hawkins CF, Hewins M (1966)Mucopolysaccharides in synovial fluid. Detection of chondroitin sulphate. Ann Rheum Dis 25: 209–213

    PubMed  CAS  Google Scholar 

  • Barnhart MI, Riddle JM, Bluhm GB (1967) Immunocytology in arthritic joints. Ann Rheum Dis 26: 281–296

    PubMed  CAS  Google Scholar 

  • Berg E, Wainwright R, Barton B, Puchtler H, McDonald T (1977) On the nature of rheumatoid rice bodies. Arthritis Rheum 20: 1343–1349

    PubMed  CAS  Google Scholar 

  • Berk RN (1967) Liquid fat in the knee joint after trauma. N Engl J Med 277: 1411–1412

    PubMed  CAS  Google Scholar 

  • Biberfeld G, Nilsson E, Biberfeld P (1979) T lymphocyte subpopulations in synovial fluid of patients with rheumatic disease. Arthritis Rheum 22: 978–982

    PubMed  CAS  Google Scholar 

  • Blankenship RM, Holmes RK, Sanford JP (1974) Treatment of disseminated gonococcal infection. N Engl J Med 290: 267–269

    PubMed  CAS  Google Scholar 

  • Blotzer JW, Myers AR (1978) Echovirus associated polyarthritis. Report of a case with synovial fluid and synovial histologic characterisation. Arthritis Rheum 21: 978–981

    PubMed  CAS  Google Scholar 

  • Bole GG (1962) Synovial fluid lipids in normal individuals and patients with rheumatoid arthritis. Arthritis Rheum 5: 589–601

    PubMed  CAS  Google Scholar 

  • Boots RH, Swift HF (1923) The arthritis of serum sickness. JAMA 80: 12–15

    Google Scholar 

  • Brant K, Cathcart ES, Cohen AS (1968) A clinical analysis of the course and prognosis of forty-two patients with amyloidosis. J Lab Clin Med 72: 631–647

    Google Scholar 

  • Brawer AE, Cathcart ES (1979) Acute monocytic arthritis. Arthritis Rheum 22: 294–300

    PubMed  CAS  Google Scholar 

  • Brenner AI, Scheinberg MA, Cathcart ES (1975) Surface characteristics of synovial-fluid and peripheral-blood lymphocytes in inflammatory arthritis. Arthritis Rheum 18: 297–303

    PubMed  CAS  Google Scholar 

  • Brook I, Reza MJ, Bricknell KS, Bluestone R, Finegold SM (1978) Synovial fluid lactic acid. A diagnostic aid in septic arthritis. Arthritis Rheum 21: 774–779

    PubMed  CAS  Google Scholar 

  • Brook I, Reza MJ, Bricknell KS, Bluestone R, Finegold SM (1980) Abnormalities in synovial fluid of patients with septic arthritis detected by gas-liquid chromatography. Ann Rheum Dis 39: 168–172

    PubMed  CAS  Google Scholar 

  • Brooks JB, Kellogg DS, Alley CC, Short HB, Handsfield HH (1974) Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis. J Infect Dis 129: 660–668

    PubMed  CAS  Google Scholar 

  • Bunch TW, Hurder GG, McDuffie FC, O’Brien PC, Markowitz H (1974) Synovial fluid complement determination as a diagnostic aid in inflammatory joint disease. Proc Mayo Clin 49: 715–720

    PubMed  CAS  Google Scholar 

  • Chambers RJ, Bywaters EGL (1963) Rubella synovitis. Ann Rhem Dis 22:263–268

    CAS  Google Scholar 

  • Cheung HS, Ryan LM, Kozin F, McCarty DJ (1980) Synovial origins of rice bodies in joint fluid. Arthritis Rheum 23: 72–76

    PubMed  CAS  Google Scholar 

  • Chisholm GD, Heard BE (1962) Oxalosis. Br J Surg 50: 78–92

    PubMed  CAS  Google Scholar 

  • Chung AC, Shanahan JR, Brown EM (1962) Synovial fluid lipids in rheumatoid and osteoarthrits. Arthritis Rheum 5: 176–183

    PubMed  CAS  Google Scholar 

  • Collins DH (1936) The pathology of synovial effusions. J Pathol Bacteriol 42: 113–140

    CAS  Google Scholar 

  • Cracchiolo A, Goldberg L, Barnett EV, Bluestone R (1971) Studies of cryoprecipitates from synovial fluids of rheumatoid patients. Immunology 20: 1067–1077

    PubMed  CAS  Google Scholar 

  • Cremer NE, Hurwitz D, Quismorio FP, Lennets EH, Frion GJ (1974) Antiviral antibodies in rheumatoid synovial fluid and cryoprecipitates. Clin Exp Immunol 18: 27–37

    PubMed  CAS  Google Scholar 

  • Currey HLF, Vernon-Roberts B (1976) Examination of synovial fluid. Clin Rheum Dis 2: 149–177

    CAS  Google Scholar 

  • Das GC, Sen SB (1968) Chylous arthritis. Br Med J 2: 27–29

    PubMed  CAS  Google Scholar 

  • De Schryver-Kecskmeti K, Tanphaichter K, Hahn B (1977) Demonstration of amyloid fibrils in synovial fluid (letter). N Engl J Med 296: 283

    Google Scholar 

  • Dieppe PA, Crocker PR, Huskisson EC, Willoughby DA (1976) Apatite deposition disease: a new arthropathy. Lancet I: 266–269

    Google Scholar 

  • Dieppe PA, Crocker PR, Corke CF, Doyle DV, Huskisson EC, Willoughby DA (1979) Synovial fluid crystals. Q J Med 48: 533–553

    PubMed  CAS  Google Scholar 

  • Edwards MS, Huber JW, Baker CJ (1978) Mycobacterium terrae synovitis and osteomyelitis. Am Rev Resp Dis 117: 161–163

    PubMed  CAS  Google Scholar 

  • Fink CW, Dich VQ, Howard J, Nelson JD (1977) Infections of bone and joints in children. Arthritis Rheum 20 (Suppl 2): 578–583

    PubMed  CAS  Google Scholar 

  • Gaucher A, Faure G, Netter P, Pourel J (1978) Single crystal identification of calcium hydrogen phosphate dihydrate in the destructive arthropathies of chondrocalcinosis. Eur J Rheumatol Inflamm 1 (2): 120–124

    Google Scholar 

  • Goldberg A, Brodsky I, McCarty D (1964) Multiple myeloma with paramyloidosis presenting as rheumatoid arthritis. Am J Med 37: 653–658

    PubMed  CAS  Google Scholar 

  • Goldenberg DL, Cohen AS (1976) Acute infectious arthritis. Am J Med 60:369–377

    PubMed  CAS  Google Scholar 

  • Goldenberg DL, Kelley W, Gibbons RB (1975) Metastatic adenocarcinoma of synovium presenting as an acute arthritis. Arthritis Rheum 18: 107–110

    PubMed  CAS  Google Scholar 

  • Gordon DA, Pruzanski W, Ogryzlo MA, Little HA (1973) Amyloid arthritis simulating rheumatoid disease in five patients with multiple myeloma. Am J Med 55: 142–154

    PubMed  CAS  Google Scholar 

  • Graham J, Goldman JA (1978) Fat droplets and synovial fluid leukocytosis in traumatic arthritis. Arthritis Rheum 21: 76–80

    PubMed  CAS  Google Scholar 

  • Gregg JR, Nixon JE, Distefano V (1978) Neutral fat globules in traumatized knees. Clin Orthop 132: 219–224

    PubMed  Google Scholar 

  • Halverson PB, McCarty DJ (1979) Identification of hydroxyapatite crystals in synovial fluid. Arthritis Rehum 22: 389–395

    CAS  Google Scholar 

  • Hamilton EBD, Bywaters EGL (1962) Joint symptoms in myelomatosis and similar conditions. Ann Rheum Dis 20: 353–362

    Google Scholar 

  • Handsfield HH, Wiesner PJ, Holmes KK (1976) Treatment of gonococcal arthritis — dermatitis syndrome. Ann Intern Med 84: 661–667

    PubMed  CAS  Google Scholar 

  • Hasselbacher P (1980) Sickled erythrocytes in synovial fluids. Arthritis Rheum 23: 127–128

    PubMed  CAS  Google Scholar 

  • Hasselbacher P, Schumacher HR (1978) Synovial fluid eosinophilia following arthrography. J Rheumatol 5: 173–176

    PubMed  CAS  Google Scholar 

  • Hedberg H (1963) Studies on the depressed haemolytic complement activity of synovial fluid in adult rheumatoid arthritis. Acta Rheum Scand 9: 165–193

    PubMed  CAS  Google Scholar 

  • Hedberg H (1964) The depressed synovial complement activity in adult and juvenile rheumatoid arthritis. Acta Rheum Scand 10: 109–127

    PubMed  CAS  Google Scholar 

  • Hollander JL (1960) The most neglected differential diagnostic test in arthritis. Arthritis Rheum 3: 364–367

    PubMed  CAS  Google Scholar 

  • Hollander JL, McCarty DJ, Astorga G, Castro-Murillo E (1965) Studies on the pathogenesis of rheumatoid joint inflammation. I. The ‘R.A.cell’ and a working hypothesis. Ann Intern Med 62: 271–280

    PubMed  CAS  Google Scholar 

  • Houig S, Gurevic P, Hoffstein S, Weissman G (1977) Crystal deposition disease. Diagnosis by electron microscopy. Am J Med 63: 161–164

    Google Scholar 

  • Hunder GG, Pierre RV (1970) In vivo LE cell formation in synovial fluid. Arthritis Rheum 13: 448–454

    PubMed  CAS  Google Scholar 

  • Huskisson EC, Doyle DV, Fowler EF, Shaw EJ (1981) Sausage digit due to radish bacillus. Ann Rheum Dis 40: 90–91

    PubMed  CAS  Google Scholar 

  • Jacobelli S, Kettlun AM, Sapag-Hagar M (1978) Inorganic pyrophosphatase activity of the synovial fluid. Kinetic and clinical study. Arthritis Rheum 21: 447–452

    PubMed  CAS  Google Scholar 

  • Jessar RA (1972) The study of synovial fluid. In: Hollander JL, McCarty DJ (eds) Arthritis and allied conditions. Lea & Febiger, Philadelphia, pp 67–81

    Google Scholar 

  • Kahn CB, Hollander JL, Schumacher HR (1970) Corticosteroid crystals in synovial fluid. JAMA 211: 807–809

    PubMed  CAS  Google Scholar 

  • Kitridou R, McCarty DJ, Prockop DJ, Hummeler K (1969a) Identification of collagen in synovial fluid. Arthritis Rheum 12: 580–588

    PubMed  CAS  Google Scholar 

  • Kitridou RC, Schumacher HR, Sharbaro JL, Hollander JL (1969b) Recurrent hemarthrosis after prosthetic knee arthroplasty: identification of metal particles in the synovial fluid. Arthritis Rheum 12: 520–528

    PubMed  CAS  Google Scholar 

  • Krey PR, Bailen DA (1979) Synovial fluid leucocytosis. A study of extremes. Am J Med 67: 436–442

    PubMed  CAS  Google Scholar 

  • MacSween RNM, Dalakos TG, Jasani MK, Boyle JA, Buchanan WW, Goudie RB (1968) A clinico-immunological study of serum and synovial fluid antinuclear factors in rheumatoid arthritis and other arthritides. Clin Exp Immunol 3: 17–24

    PubMed  CAS  Google Scholar 

  • Male D, Roitt IM, Hay FC (1980) Analysis of immune complexes in synovial effusions of patients with rheumatoid arthritis. Clin Exp Immunol 39: 297–306

    PubMed  CAS  Google Scholar 

  • Malinin TI, Pekin Ti, Zvaifler N (1967) Cytology of synovial fluid in rheumatoid arthritis. Am J Clin Pathol 47: 203–208

    PubMed  CAS  Google Scholar 

  • McCarty DJ, Hogan JM (1964) Inflammatory reaction after intrasynovial injection of microcrystalline adrenocorticosteroid esters. Arthritis Rheum 7: 359–367

    PubMed  Google Scholar 

  • Mellbye OJ, Munthe E (1971) Specific binding of immunoconglutinin in tissues and synovial fluids from patients with rheumatoid arthritis. Clin Exp Immunol 8: 713–722

    PubMed  CAS  Google Scholar 

  • Mellbye OJ, Natvig JB (1971) Evidence for immune complexes containing antibody to the pepsin site of IgG in rheumatoid synovial fluids. Clin Exp Immunol 8: 889–899

    PubMed  CAS  Google Scholar 

  • Mellbye OJ, Messner RP, DeBord JR, Williams RC (1972) Immunoglobulin and receptors for C3 on lymphocytes from patients with rheumatoid arthritis. Arthritis Rheum 15: 371–380

    PubMed  CAS  Google Scholar 

  • Munthe E, Natvig JB (1971) Characterization of IgG complexes in eluates from rheumatoid tissue. Clin Exp Immunol 8: 249–262

    PubMed  CAS  Google Scholar 

  • Natvig JB, Munthe E (1975) Self-associating IgG rheumatoid factor represents a major response of plasma cells in rheumatoid inflammatory tissue. Ann NY Acad Sci 256: 88–92

    PubMed  CAS  Google Scholar 

  • Newcombe DS, Cohen AS (1963) Chylous joint effusion: A study of intraarticular lipid synthesis (abstract). J Clin Invest 42: 960

    Google Scholar 

  • Onion DK, Crumpacker CS, Gulliland BC (1971) Arthritis of hepatitis associated with Australia antigen. Ann Intern Med 75: 29–33

    PubMed  CAS  Google Scholar 

  • Panush RS, Franco AE, Schur PH (1971) Rheumatoid arthritis associated with eosinophilia. Ann Intern Med 75: 199–205

    PubMed  CAS  Google Scholar 

  • Pascual-Gomez E (1980) Identification of large mononuclear cells in varicella arthritis. Arthritis Rheum 23: 519–520

    PubMed  CAS  Google Scholar 

  • Pekin TJ, Zvaifler NJ (1964) Hemolytic complement in synovial fluid. J Clin Invest 43: 1372–1382

    PubMed  CAS  Google Scholar 

  • Pekin TJ, Zvaifler NJ (1970) Synovial fluid findings in systemic lupus erythematosus (SLE). Arthritis Rheum 13: 777–785

    PubMed  Google Scholar 

  • Pekin TJ, Malinin TI, Zvaifler NJ (1967) Unusual synovial fluid findings in Reiter’s syndrome. Ann Intern Med 66: 677–684

    PubMed  Google Scholar 

  • Phelps P, Steele AJ, McCarty DJ (1968) Compensated polarized light microscopy identification of crystals in synovial fluids from gout and pseudogout. JAMA 203: 508–512

    PubMed  CAS  Google Scholar 

  • Pope RM, Mannik M, Gilliland BC, Teller DC (1975) The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self association of IgG rheumatoid factors. Arthritis Rheum 18: 97–106

    PubMed  CAS  Google Scholar 

  • Rawson AJ, Abelson NJ, Hollander JL (1965) Studies on the pathogenesis of rheumatoid joint inflammation. II. Intracytoplasmic particulate complexes in rheumatoid synovial fluids. Ann Intern Med 62: 281–284

    PubMed  CAS  Google Scholar 

  • Reddy CRRM, Parvathi G, Swaramappa M (1969) Adhesion of white cells to Guinea-worm larvae. Am J Trop Med Hyg 18: 379–381

    PubMed  CAS  Google Scholar 

  • Rodnan GP, Eisenbeis C, Creighton AS (1962) On the occurrence of rheumatoid factor in synovial fluid (abstract). Arthritis Rheum 5: 316

    Google Scholar 

  • Ropes M, Bauer W (1953) Synovial fluid changes in joint disease. Harvard University Press, Cambridge

    Google Scholar 

  • Ropes MW, Muller AF, Bauer W (1960) The entrance of glucose and other sugars into joints. Arthritis Rheum 3: 496–514

    PubMed  CAS  Google Scholar 

  • Sandson J, Hamerman D (1958) Paper electrophoresis of human synovial fluid. Proc Soc Exp Biol Med 98: 564–566

    PubMed  CAS  Google Scholar 

  • Schmid K, MacNair M (1956) Characterization of the proteins of human synovial fluid in certain disease states. J Clin Invest 35: 814–824

    PubMed  CAS  Google Scholar 

  • Schumacher HR (1966) Intracellular crystals in synovial fluid anticoagulated with oxalate. N Engl J Med 274: 1372–1373

    PubMed  CAS  Google Scholar 

  • Schumacher HR (1976) Ultrastructural findings in chondrocalcinosis and pseudogout. Arthritis Rheum 19: 413–425

    PubMed  Google Scholar 

  • Schumacher HR, Andrews R, McLaughlin G (1973) Arthropathy in sickle cell disease. Ann Intern Med 78: 203–211

    PubMed  CAS  Google Scholar 

  • Schumacher HR, Jimenez SA, Gibson T, Pascual E, Traycoff R, Dorwart BB, Regina-to AJ (1975) Acute gouty arthritis without urate crystals identified on initial examination of synovial fluid. Arthritis Rheum 18: 603–612

    Google Scholar 

  • Schumacher HR, Smolyo AP, Tse RL, Maurer K (1977) Arthritis associated with apatite crystals. Arch Intern Med 84: 411–416

    Google Scholar 

  • Schur PH, Sandson J (1963) Immunologic studies of the proteins of human synovial fluid. Arthritis Rheum 6: 115–129

    PubMed  CAS  Google Scholar 

  • Seifert MH, Mathews JA, Phillips I, Gargan RA (1978) Gas-liquid chromatography in the diagnosis of pyogenic arthritis. BMJ 2: 1402

    Google Scholar 

  • Sheldon PJ, Papamichail M, Holborrow EJ (1974) Studies on synovial fluid lymphocytes in rheumatoid arthritis. Ann Rheum Dis 33: 509–514

    PubMed  CAS  Google Scholar 

  • Smiley JD, Sachs SC, Ziff M (1968) In vitro synthesis of immunoglobulin by rheumatoid synovial membrane. J Clin Invest 47: 624–632

    PubMed  CAS  Google Scholar 

  • Smith C, Hamerman D (1962) Acid phosphatase in human synovial fluid. Arthritis Rheum 5: 11–14

    PubMed  CAS  Google Scholar 

  • Smith JW, Sanford JP (1967) Viral arthritis. Ann Intern Med 67: 651–654

    PubMed  CAS  Google Scholar 

  • Spriggs AI, Boddington MM, Mowat AG (1978) Joint fluid cytology in Reiter’s disease. Ann Rheum Dis 37: 557–560

    PubMed  CAS  Google Scholar 

  • Traycoff RB, Pascual E, Schumacher HR (1976) Mononuclear cells in human synovial fluid. Identification of lymphoblasts in rheumatoid arthritis. Arthritis Rheum 19: 743–748

    PubMed  CAS  Google Scholar 

  • Treuhaft PS, McCarty DJ (1971) Synovial fluid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases. Arthritis Rheum 14:475–484 Utsinger PD (1975) Synovial fluid lymphocytes in rheumatoid arthritis. Arthritis Rheum 18: 595–602

    Google Scholar 

  • Van de Putte LBA, Meijer CJLM, Lafeber GJM, Kleinjan R, Cats A (1976) Lmyphocytes in rheumatoid and non rheumatoid synovial fluids. Non-specificity of high T cell and low B cell percentages. Arthritis Rheum 35: 451–455

    Google Scholar 

  • Vaughan JH, Barnett EV, Sobel MV (1968) Intracytoplasmic inclusions of immuno- globulins in rheumatoid arthritis and other diseases. Arthritis Rheum 11: 125–134

    PubMed  CAS  Google Scholar 

  • Vernon-Roberts B, Freeman MAR (1976) Morphological and analytical studies of the tissues adjacent to joint prostheses: investigations into the causes of loosening of prostheses. In: Schaldach M, Hohmann D (eds) Advances in artificial hip and knee joint replacement. Springer, Berlin Heidelberg New York, pp 148–186

    Google Scholar 

  • Vernon-Roberts B, Currey HLF, Perrin J (1974) T and B cells in the blood and synovial fluid of rheumatoid patients. Ann Rheum Dis 33: 430–434

    PubMed  CAS  Google Scholar 

  • Wands JR, Mann E, Alpert E, Isselbacher KL (1975) The pathogenesis of arthritis associated with acute hepatitis B surface antigen-positive hepatitis. J Clin Invest 55: 930–936

    PubMed  CAS  Google Scholar 

  • Ward TT, Steigbigel RT (1978) Acidosis of synovial fluid correlates with synovial fluid leukocytosis. Am J Med 64: 933–936

    PubMed  CAS  Google Scholar 

  • Winchester RJ, Agnella V, Kunkel MG (1969) The joint fluid yG-globulin complexes and complement diminution. Ann NY Acad Sci 168: 195–203

    PubMed  CAS  Google Scholar 

  • Winchester RJ, Winfield JB, Siegal FB, Wenet P, Bentwich ZH, Kunkel HG (1974) Analysis of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. J Clin Invest 54: 1082–1092

    PubMed  CAS  Google Scholar 

  • Winchester RS, Litwin SD, Koffler D, Kunkel HG (1971) Observations on the eosinophilia of certain patients with rheumatoid arthritis. Arthritis Rheum 14:650–665

    PubMed  CAS  Google Scholar 

  • Wolf AW, Benson DR, Shiji H, Riggins RS, Shapiro RF, Castles JJ, Wild J (1978) Cur-rent concepts in synovial fluid analysis. Clin Orthop 134: 261–265

    PubMed  Google Scholar 

  • Wynne-Roberts CR, Cassidy JT (1979) Juvenile rheumatoid arthritis with rice bodies: light and electron microscopic studies. Ann Rheum Dis 38: 8–13

    PubMed  CAS  Google Scholar 

  • Zuckner J, Uddin J, Jamal L, Gantner G, Dorner R (1964) Cholesterol crystals in synovial fluid. Ann Intern Med 60: 436–446

    PubMed  CAS  Google Scholar 

  • Zvaifler NJ (1973) The immunopathology of joint inflammation in rheumatoid arthritis. Adv Immunol 16: 265–336

    PubMed  CAS  Google Scholar 

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  1. P. A. Revell
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Editors and Affiliations

  1. Department of Morbid Anatomy, The London Hospital Medical College, E1 1BB, GB-London, UK

    C. L. Berry Professor Dr.

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Revell, P.A. (1982). Examination of Synovial Fluid. In: Berry, C.L. (eds) Bone and Joint Disease. Current Topics in Pathology, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68382-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-68382-4_1

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