Skip to main content
SpringerLink
Log in

Perspectives on Endogenous Retroviruses in Normal and Pathological Growth

  • Chapter
Retrovirus Genes in Lymphocyte Function and Growth

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 98))

  • 42 Accesses

Abstract

Thirty years have passed since Gross (1951) first reported that the heritable lymphoma of AKR mice could be transmitted to other mice by a virus. Subsequent studies on lymphoma in X-irradiated C3H mice (Gross 1959) and C57 BL mice (Lieberman and Kaplan 1959) led Latarjet and Duplan (1962) to suggest that the activation of a latent virus in radiation leukemogenesis was akin to induction of lysogenic bacteriophage. While Temin’s DNA provirus hypothesis (1964) provided a molecular model for the chromosomal inheritance of retrovirus genomes, this concept was not accepted by most virologists until the discovery of reverse transcriptase in 1970. By then convincing data had also accrued to reveal that retrovirus genes existed as host genetic traits in mice and chickens.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bentvelzen P, Daams JH (1969) Hereditary infections with mammary tumor viruses in mice. J Natl Cancer Inst 43:1025–1035

    PubMed  CAS  Google Scholar 

  • Benveniste RE, Todaro GJ (1974) Evolution of C-type viral genes: inheritance of exogenously acquired viral genes. Nature 252:456–459

    Article  PubMed  CAS  Google Scholar 

  • Cloyd MW, Hartley JW, Rowe WP (1980) Lymphomagenicity of recombinant mink cell focus-forming murine leukemia viruses. J Exp Med 151:542–552

    Article  PubMed  CAS  Google Scholar 

  • Coffin JM, Tsichlis PN, Robinson HL (1981) Genetics of leukemogenesis by avian leukosis viruses. In: Neth R, Gallo RC, Mannweiler K, Winkler K (eds) Modern trends in human leukemia. Springer, Berlin Heidelberg New York, pp 432–438

    Chapter  Google Scholar 

  • Cooper GM, Neiman PE (1980) Transforming genes of neoplasms induced by avian lymphoid leukosis viruses. Nature 287:656–658

    Article  PubMed  CAS  Google Scholar 

  • Crittenden LB, Witter RL, Fadly AM (1979) Low incidence of lymphoid tumors in chickens continuously producing endogenous virus. Avian Dis 23:646–650

    Article  PubMed  CAS  Google Scholar 

  • Crittenden LB, Hayward WS, Hanafusa H, Fadly AM (1980) Induction of neoplasms by subgroup E recombinants of exogenous and endogenous avian retro viruses (Rous-associated virus type 60). J Virol 33:915–919

    PubMed  CAS  Google Scholar 

  • Doolittle WF, Sapienza C (1980) Selfish genes, the phenotypic paradigm and genome evolution. Nature 284:601–603

    Article  PubMed  CAS  Google Scholar 

  • Elder JH, Jensen FC, Bryant ML, Lerner RA (1977) Polymorphism of the major envelope glycoprotein (gp70) of murine C-type viruses: virion associated and differentiation antigens encoded by a multigene family. Nature 267:23–28

    Article  PubMed  CAS  Google Scholar 

  • Frisby DP, Weiss RA, Roussel M, Stehelin D (1979) The distribution of endogenous retrovirus sequences in the DNA of galliform birds does not coincide with avian phylogenetic relationships. Cell 17:623–634

    Article  PubMed  CAS  Google Scholar 

  • Frisby D, MacCormick R, Weiss RA (1980) Origin of RAV-0, the endogenous retrovirus of chickens. In: Viruses in naturally occurring cancers. Essex M, Todaro GJ, Zur Hausen H (eds) Cold Spring Harbor Laboratory, pp 509–517

    Google Scholar 

  • Gross L (1951) “Spontaneous” leukemia developing in C3H mice following inoculation, in infancy, with AK-leukemic extracts, or AK embryos. Proc Soc Exp Biol Med 76:27–32

    PubMed  CAS  Google Scholar 

  • Gross L (1959) Serial cell-free passage of a radiation-activated mouse leukemia agent. Proc Soc Exp Biol Med 100:325–328

    PubMed  CAS  Google Scholar 

  • Hayward WS, Neel BG, Astrin SM (1981) Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature 290:475–480

    Article  PubMed  CAS  Google Scholar 

  • Latarjet R, Duplan J-F (1962) Experiment and discussion on leukaemogenesis by cell free extracts of radiation-induced leukaemia in mice. Int J Radiation Biol 5:339–344

    Article  CAS  Google Scholar 

  • Levy JA (1978) Xentotropic type C viruses. Curr Top Microbiol Immunol 79:111–213

    Article  PubMed  CAS  Google Scholar 

  • Liebermann M, Kaplan HS (1959) Leukemogenic activity of filtrates from radiation — induced lymphoid tumors of mice. Science 130:387–388

    Article  Google Scholar 

  • McGrath MS, Weissman IL (1979) AKR leukemogenesis: identification and biological significance of thymic lymphoma receptors for AKR retroviruses. Cell 17:65–75

    Article  PubMed  CAS  Google Scholar 

  • Neiman PE, Jordan L, Weiss RA, Payne LN (1980) Malignant lymphoma of the bursa of Fabricius: analysis of early transformation. In: Essex M, Todaro GJ, Zur Hausen H (eds) Viruses in naturally occurring cancers. Cold Spring Harbor Laboratory, pp 519–528

    Google Scholar 

  • Orgel LE, Crick FNC (1980) Selfish DNA: the ultimate parasite. Nature 284:604–607

    Article  PubMed  CAS  Google Scholar 

  • Payne LN, Chubb RC (1968) Studies on the nature and genetic control of an antigen in normal chick embryos which react in the COFAL test. J Gen Virol 3:379–391

    Article  PubMed  CAS  Google Scholar 

  • Reitz MS, Poiesz B J, Ruscetti FW, Gallo RC (1981) Characterization and distribution of nucleic acid sequences of a novel retrovirus isolated from neoplastic human T-lymphocytes. Proc Natl Acad Sci USA 78:1887–1891

    Article  PubMed  CAS  Google Scholar 

  • Rosenthal PN, Robinson HL, Robinson WS, Hanafusa T, Hanafusa H (1971) DNA in uninfected and virus infected cells complementary to avian tumor virus RNA. Proc Natl Acad Sci USA 68:2336–2340

    Article  PubMed  CAS  Google Scholar 

  • Rowe WP, Hartley JW, Lander MR, Pugh WE, Teich NM (1971) Non-infectious AKR mouse embryo cell lines in which each cell has the capacity to be activated to produce infectious murine leukemia virus. Virology 46:866–876

    Article  PubMed  CAS  Google Scholar 

  • Stockert E, Old LJ, Boyse EA (1971) The GIX system. A cell surface alloantigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome. J Exp Med 133:1334–1335

    Article  PubMed  CAS  Google Scholar 

  • Taylor BA, Meier H, Meyers DD (1971) Host gene control of C-type RNA tumor virus: inheritance of the group-specific antigen of murine leukemia virus. Proc Natl Acad Sci USA 68:3190–3194

    Article  PubMed  CAS  Google Scholar 

  • Temin HM (1964) Nature of the provirus of Rous sarcoma. Natl Cancer Inst Monogr 17:557–570

    Google Scholar 

  • Temin HM (1974) On the origin of RNA tumor viruses. Annu Rev Genet 8:155–157

    Article  PubMed  CAS  Google Scholar 

  • Temin HM (1980) Origin of retrovirus from cellular moveable genetic elements. Cell 21:599–600

    Article  PubMed  CAS  Google Scholar 

  • Todaro GJ (1980) Interspecies transmission of mammalian retroviruses. In: Klein G (ed) Viral oncology, Raven Press, New York, pp 291–309

    Google Scholar 

  • Varmus HE, Weiss RA, Friis RR, Levinson W, Bishop JM (1972) Detection of avian tumor virus-specific nucleotide sequences in avian cell DNA. Proc Natl Acad Sci USA 69:20–24

    Article  PubMed  CAS  Google Scholar 

  • Vogt PK, Friis RR (1971) An avian leukosis virus related to RSV(0): properties and evidence for helper activity. Virology 43:223–234

    Article  PubMed  CAS  Google Scholar 

  • Weiss RA (1965) Genetic transmission of RNA tumor viruses. Perspect Virol 9:165–187

    Google Scholar 

  • Weiss RA, Biggs PM (1972) Leukosis and Marek’s disease viruses of feral red jungle fowl and domestic fowl in Malaya. J Natl Cancer Inst 49:1713–1725

    PubMed  CAS  Google Scholar 

  • Weiss RA, Frisby DP (1982) Are avian endogenous viruses pathogenic? In: Yohn DS (ed) Xth Internat Symp Comp Res Leukemia (in press)

    Google Scholar 

  • Weiss RA, Payne LN (1971) The heritable nature of the factor in chicken cells which acts as a helper virus for Rous sarcoma virus. Virology 45:508–515

    Article  PubMed  CAS  Google Scholar 

  • Weiss RA, Friis RR, Katz E, Vogt PK (1971) Induction of avian tumor viruses in normal cells by physical and chemical carcinogens. Virology 46:920–938

    Article  PubMed  CAS  Google Scholar 

  • Weissman A (1893) The germ-plasm: a theory of heredity (Translated by WN Parker and H Rönn-feldt) London, W Scott

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

    Robin A. Weiss

Authors
  1. Robin A. Weiss
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut für Virologie und Immunbiologie, Universität Würzburg, Versbacher Str. 7, 8700, Würzburg, Deutschland

    Eberhard Wecker  & Ivan Horak  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Weiss, R.A. (1982). Perspectives on Endogenous Retroviruses in Normal and Pathological Growth. In: Wecker, E., Horak, I. (eds) Retrovirus Genes in Lymphocyte Function and Growth. Current Topics in Microbiology and Immunology, vol 98. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68369-5_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68369-5_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68371-8

  • Online ISBN: 978-3-642-68369-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation