Abstract
The last decade has witnessed great advances in the investigation and study of the lymphoreticular system. In particular, new methods of cell identification have allowed us to group certain diseases together as disorders of a particular cell type. In this way, mycosis fungoides, Sézary syndrome, and certain other skin disorders previously described as “reticulum cell sarcoma”, “well differentiated lymphocytic lymphoma”, or “histiocytic lymphoma” have been unified as manifestations of malignant T cell proliferations [1,2,3]. The frequency with which lymphoreticular neoplasms involving broad expanses of skin are T cell malignancies is in marked contrast to those which spare the skin. In adults, lymphocytic malignancies which do not have prominent associated skin infiltration are most commonly proliferations of B cells [4].
Supported by NIH Grants CA 20499, CA 13696 and RR 00645
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Chu, A., Berger, C.L., Lynfield, Y., Esseesse, I., Edelson, R.L. (1982). Pathogenesis of Cutaneous T Cell Lymphoma. In: Goos, M., Christophers, E. (eds) Lymphoproliferative Diseases of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68363-3_6
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DOI: https://doi.org/10.1007/978-3-642-68363-3_6
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