Abstract
The lymphatic tissue of the immunologic organs is composed of a great number of different cells. (Mori and Lennert 1969; Weiss 1972; Olah et al. 1975). This great number was reduced by the introduction of cell systems for the different cells. This was done for the lymphatic and the phagocytic cells. (Langevoort et al. 1970; Lennert 1978). Besides the endothelial cells of the blood and lymph vessels there remain the stationary cells of the lymphatic tissue. These cells have been called reticulum cells (in English mostly reticular cells) for quite some time. Unfortunately, up to now there is troublesome inconsistency in this term (review see Müller-Hermelink and Lennert 1978). Some authors (Müller-Hermelink and Lennert 1978) named cells of different origin and with different function reticulum cells while others (Carr 1976) reject this term completely
Reticulum cell with several ensheathed connective tissue fibers (▸). In the cytoplasm directly adjoining the fibers are fine bundles of filaments (→). Human spleen, x 10900
Schematic representation of the difference between fibrocytes and reticulum cells. A A fibrocyte is a connective tissue cell which is more or less completely surrounded by fibrous material. B A reticulum cell is a connective tissue cell attached to fibrous material at distinctive circumscript areas, often ensheating this material
and call all the connective tissue cells including the stroma cells of the lymphatic tissue fibroblasts in the sense of fiber forming cells. Therefore, we have to prove the existence of stroma cells of the lymphatic tissue as a definite cell type, which can be distinguished from other stationary cells of the lymphatic tissue and also from other stroma cells of connective tissue.
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References
Carr I (1976) The RES and the mononuclear phagocytic system. In: Reichard SM, Escobar MR, Friedman H (eds) The Reticulo-endothelial system in health and disease. Plenum Press, New York London, p 3–9
van Furth R, Cohn ZA, Hirsch JG, Humphrey JH, Spector WG, Langevoort HL (1972) The mononuclear phagocyte system: A new classification of macrophages, monocytes and their precursor cells. Bull WH 46: 845–852
Heusermann U, Stutte HJ, Müller-Hermelink HK (1974) Interdigitating cells in the white pulp of the human spleen. Cell Tissue Res 153: 415–417
Heusermann U, Stutte HJ (1977) Enzymhistochemische, histometrische und ultrastrukturelle Untersuchungen von Milzen bei der Vinylchlorid-Krankheit. Virchows Arch [Pathol Anat] 375: 303–317
Heusermann U, Zurborn KH, Schroeder L, Stutte HJ (1980) The Origin of the dendritic reticulum cell Cell Tissue Res 209: 279–294
Hoefsmit ECM, Kamperdijk ED WA, Hendricks HR, Beelen RHJ, Balfour BM (1980) Lymph node macrophages. In: Carr J, Daems WT (eds) Vol 1. Plenum Press, New York London, p 417–468
Kamperdijk EWA, Raaymakers EM, De Leeuw JHS, Hoefsmit EChM (1978) Lymph node macrophages and reticulum cells in the immune response. I. The primary response to paratyphoid vaccine. Cell Tissue Res 192: 1–23
Kaiserling E, Lennert K (1974) Die interdigitierende Retikulumzelle im menschlichen Lymphknoten. Eine spezifische Zelle der thymusabhängigen Region. Virchows Archiv [Cell Pathol] 16: 51–61
Langevoort HL, Cohn ZA, Hirsch JG, Humphrey JH, Spector WG, Van Furth R (1970) The nomenclature of mononuclear phagocyte cells: a proposal for a new classification. In: Van Furth R (ed) Mononuclear Phagocytes. Oxford, Blackwell, p 1–6
Lennert K (1978) Classification of non- Hodgkin’s lymphomas. In: Uehlinger E (Hrsg) Malignant Lymphomas other than Hodgkin’s Disease. (Lennert K) Handb Spez Pathol Anat Histol Bd I/38. Springer, Berlin Heidelberg New York, p 83–110
Mitchel J, Abbot A (1965) Ultrastructure of antigen-retaining reticulum of lymph node follicles as shown by high resolution autoradiography. Nature 208: 500–502
Mori Y, Lennert K (1969) Electron microscopic atlas of lymph node cytology and pathology. Springer, Berlin Heidelberg New York
Müller-Hermelink HK, Heusermann U, Stutte HJ (1974) Enzyme histochemical observation on the localization and structure of the T cell and B cell regions in the human spleen. Cell Tissue Res 154: 167–179
Müller-Hermelink HK, Lennert K (1978) The cytologic, histologic and functional basis for a modern classification of lymphomas. In: Uehlinger E (Hrsg) Malignant lymphomas other than Hodgkin’s Disease. (Lennert K) Handb Spez Pathol Anat Histol, Bd I/38. Springer, Berlin Heidelberg New York, p 1–71
Nossal GJV, Abbot A, Mitchell J, Lummus Z (1968) Antigens in immunity. XV. Ultrastructure features of antigen capture in primary and secondary lymphoid follicles. J Exp Med 127: 277–290
Olàh I, Röhlich P, Törò I (1975) Ultrastructure of lymphoid organs. An electron-microscope atlas. Masson, Paris
van Rooijen N (1977) Immune complexes in the spleen: three concentric follicular areas of immune complex trapping, their interrelationships and possible function. J. Reticulo-endothel Soc 21: 143–151
Sordat B, Sordat M, Hess MW, Stoner RD, Cottier H (1970) Specific antibody within lymphoid germinal center cells of mice after primary immunization with horseradish peroxidase: a light and electron-microscopic study. J Exp Med 131: 77–92
Veerman AJP (1975) The postnatal development of the white pulp in the rat spleen and the onset of immunocompetence against the thymus-independent and a thymus-dependent antigen. Z Immunol Forsch 150: 45–59
Veerman AJP, van Rooijen N (1975) Lymphocyte capping and lymphocyte migration as associated events in the in vivo antigen trapping process. An electron-microscopic autoradiographic study in the spleen of mice. Cell Tissue Res 161: 211–217
Watanabe S, Watanabe K, Ohishi T, Kageyama K (1979) The development of extranodal lymphoid follicles in experimental bronchopneumonia. Acta Pathol Jpn 29: 533–543
Weiss L (1972) The cells and tissues of the immune system. Structure, functions, interactions. Prentice Hall Inc, Englewood Cliffs
White RG, French VJ, Stark JM (1967) Germinal center formation and antigen localization in Malpighian bodies of the chicken spleen. In: Cottier H, Odartchenko N, Schindler R, Congdon CC (Hrs) Germinal Centers in Immune Responses, Springer, Berlin Heidelberg New York, p 120–142
Wiersbowsky A, Grouls V, Helpap B, Klingmüller G (1980) Ultrastrukturelle Untersuchungen zur Herkunft der interdigitierenden Zellen. VIII. Jahrestagung der Arbeits- gemeinschaft Dermatologische Forschung Innsbruck
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Heusermann, U., Schroeder, L., Zurborn, K.H., Stutte, H.J. (1982). Structure and Function of Stroma Cells in Lymphoid Tissues. In: Goos, M., Christophers, E. (eds) Lymphoproliferative Diseases of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68363-3_3
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DOI: https://doi.org/10.1007/978-3-642-68363-3_3
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