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Effect of 5 kg/cm2 Pressure on Atherosclerotic Vessel Wall Segments

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Transluminal Coronary Angioplasty and Intracoronary Thrombolysis

Abstract

Dotter and Judkins as well as Grüntzig ascribed the reopening of atherosclerotic obstructions achieved by transluminal angioplasty partially to a compression of atheromatous material [4, 6]. As a simplified model for the effect of angioplasty the compression of snow was taken. Several experiments performed in animals [1, 2, 9] and human postmortem coronary arteries [1, 3, 5, 7, 8] predominantly revealed changes described as desquamation of endothelial cells, splitting of vessel wall layers, and breaks of elastic fibrils. Compression of fluid-containing tissue appears not possible, since fluid is incompressible. This experimental study was performed to reveal the influence of 5 atm pressure on the morphology and the weight of postmortem atherosclerotic vessel wall segments.

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References

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Author information

Authors and Affiliations

  1. Department of Cardiology and Pathology, University Hospital, Theodor-Stern-Kai 7, 6000, Frankfurt a.M., Germany

    M. Kaltenbach, J. Beyer, H. Klepzig, L. Schmidts & K. Hübner

Authors
  1. M. Kaltenbach
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  2. J. Beyer
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  3. H. Klepzig
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  4. L. Schmidts
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  5. K. Hübner
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Editor information

Editors and Affiliations

  1. Abteilung für Kardiologie, Zentrum der Inneren Medizin, Klinikum der Johann Wolfgang Goethe-Universität, Theodor-Stern-Kai 7, 6000, Frankfurt/Main 70, Germany

    Martin Kaltenbach  & Wulf-Dirk Bussmann  & 

  2. School of Medicine, Department of Medicine, Emory University, 1364 Clifton Road, Atlanta, Georgia, 30322, USA

    Andreas Roland Grüntzig M.D. (Professor of Medicine) (Professor of Medicine)

  3. Division of Cardiology, Mount Sinai Medical Center, One Gustave L. Levy Place, New York, N.Y., 10029, USA

    Klaus Peter Rentrop M.D. (Associated Professor of Medicine) (Associated Professor of Medicine)

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© 1982 Springer-Verlag Berlin Heidelberg

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Kaltenbach, M., Beyer, J., Klepzig, H., Schmidts, L., Hübner, K. (1982). Effect of 5 kg/cm2 Pressure on Atherosclerotic Vessel Wall Segments. In: Kaltenbach, M., Grüntzig, A.R., Rentrop, K.P., Bussmann, WD. (eds) Transluminal Coronary Angioplasty and Intracoronary Thrombolysis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68358-9_28

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  • DOI: https://doi.org/10.1007/978-3-642-68358-9_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68360-2

  • Online ISBN: 978-3-642-68358-9

  • eBook Packages: Springer Book Archive

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