Summary
Eleven patients suffering from metastases to the lumbar spine or pelvis received multiple intrathecal injections of 0.5–1.5 mg morphine. The first injection produced pain relief for 18–84 hours. A hypoalgesia following the intrathecal injection persisted up to 4 days. No change in blood pressure or heart rate was noted.
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Behar M, Magora F, Olshwang D, Davidson JT (1979) Epidural Morphine in treatment of pain. Lancet 1:527
Davies GK, Tohurst-Cleaver CL, James TL (1980) CNS depression from intrathecal morphine. Anesthesiology 52:280
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© 1982 Springer-Verlag Berlin Heidelberg
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Kossmann, B., Driessen, A., Mehrkens, H.H., Dick, W. (1982). Intrathecally Applied Morphine for Treatment of Postoperative and Chronic Pain. In: Yaksh, T.L., Müller, H. (eds) Spinal Opiate Analgesia. Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine, vol 144. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68261-2_21
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DOI: https://doi.org/10.1007/978-3-642-68261-2_21
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-11036-1
Online ISBN: 978-3-642-68261-2
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