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Kinin-Releasing Pancreatic Proteinase Kallikrein

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Treatment of Male Infertility

Abstract

Pancreatic kallikrein, a kinin-releasing proteinase, has recently been demonstrated to be a possible new therapeutic agent in some forms of male infertility (Schill 1979a). Andrological therapy in general is largely empiric and, therefore, often unsuccessful. However, through the introduction of this tissue hormone-releasing proteinase the spectrum of andrological therapy is broadened, especially in cases of idiopathic normogonadotropic oligozoospermia and asthenozoospermia. This report will summarize the available experimental and clinical data about the efficacy of kallikrein and the kallikrein-kinin system in andrology and will discuss the practical aspects of kallikrein treatment.

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Authors
  1. W. B. Schill
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Editors and Affiliations

  1. Division of Endocrinology and Metabolism, University of Toronto and Mount Sinai Hospital, 600 University Avenue; Suites 639-640, M5G 1X5, Toronto, Ontario, Canada

    Jerald Bain M.D.

  2. Dermatologische Klinik und Poliklinik der Universität München, Frauenlobstr. 9-11, 8000, München 2, West Germany

    Wolf-B. Schill

  3. Grupo de Estudio en Fertilidad y Endocrinologia de Rosario, Cordoba 1764, 2000, Rosario (SF), Argentina

    Luis Schwarzstein

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Schill, W.B. (1982). Kinin-Releasing Pancreatic Proteinase Kallikrein. In: Bain, J., Schill, WB., Schwarzstein, L. (eds) Treatment of Male Infertility. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68223-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-68223-0_10

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