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Metabolic Interconversion of Enzymes 1980 pp 372–377Cite as

The Acetylcholine Receptor: Control of Its Synthesis, Stability, and Cell Surface Distribution

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Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

Nicotinic acetylcholine receptors (AChR) mediate signal reception and transduction at neuromuscular and interneuronal synapses of vertebrates. Binding of the neurotransmitter acetylcholine or its agonists to AChR induces a conformational change in this receptor molecule which leads to the opening of transmembrane channels permeable to sodium and potassium ions. The resulting ion fluxes depolarize the post-synaptic membrane and thus induce a propagated action potential.

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Author information

Authors and Affiliations

  1. Max-Planck-Institut für Psychiatrie, 8033, Martinsried, Germany

    H. Betz

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  1. H. Betz
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Editor information

Editors and Affiliations

  1. Biochemisches Institut, Albert-Ludwigs-Universität, Hermann-Herder-Str. 7, 7800, Freiburg, Germany

    Helmut Holzer

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© 1981 Springer-Verlag, Berlin Heidelberg

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Betz, H. (1981). The Acetylcholine Receptor: Control of Its Synthesis, Stability, and Cell Surface Distribution. In: Holzer, H. (eds) Metabolic Interconversion of Enzymes 1980. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68211-7_36

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  • DOI: https://doi.org/10.1007/978-3-642-68211-7_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68213-1

  • Online ISBN: 978-3-642-68211-7

  • eBook Packages: Springer Book Archive

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