The Acetylcholine Receptor: Control of Its Synthesis, Stability, and Cell Surface Distribution
Nicotinic acetylcholine receptors (AChR) mediate signal reception and transduction at neuromuscular and interneuronal synapses of vertebrates. Binding of the neurotransmitter acetylcholine or its agonists to AChR induces a conformational change in this receptor molecule which leads to the opening of transmembrane channels permeable to sodium and potassium ions. The resulting ion fluxes depolarize the post-synaptic membrane and thus induce a propagated action potential.
KeywordsCarbohydrate Retina Methionine Choline Acetylcholine
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