Long Term and Sequential Hemodynamic Investigations in Patients With lonescu-Shiley Pericardial Xenografts

  • D. R. Smith
  • A. P. Tandon
  • S. S. Hassan
  • M. I. Lonescu
Conference paper


The glutaraldehyde stabilized pericardial xenograft1 has been in clinical use since 1971 and has gained much wider usage since 1976 when it was released for general use. The clinical experience has been gratifying (6, 7, 10). We present herewith the reults of hemodynamic investigations undertaken in 75 patients with pericardial xenograft heart valve replacement.


Cardiac Index Valve Replacement Aortic Valve Replacement Mitral Valve Replacement Valve Prosthesis 
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  1. 1.
    Björk VO, Holmgren A, Olin C, Ovenfors C (1971) Clinical and haemodynamic results of aortic valve replacement with the Björk-Shiley tilting disc valve prosthesis Scand J Thorac Cardiovasc Surg 5:177Google Scholar
  2. 2.
    Book K (1974) Mitral valve replacement with Björk-Shiley tilting disc valve - A clinical and haemodynamic study in patients with isolated mitral valve lesions. Scand J Thorac Cardiovasc Surg [Suppl 2] 12Google Scholar
  3. 3.
    Bristow JD, Kremkau EL (1975) Hemodynamic changes after valve replacement with Starr-Edwards prostheses. Am J Cardiol 35:716PubMedCrossRefGoogle Scholar
  4. 4.
    Cohn LH, Sanders JH, Collins JJ (1976) Aortic valve replacement with the Hancock porcine xenograft. Ann Thorac Surg 22:221PubMedCrossRefGoogle Scholar
  5. 5.
    Hulgren H, Hubis H, Shumway NE (1968) Cardiac functions following mitral valve replacement. Am Heart J 75:302CrossRefGoogle Scholar
  6. 6.
    Ionescu MI, Tandon AP (1979) The Ionescu-Shiley pericardial xenograft heart valve. In: Ionescu MI (ed) Tissue heart valves. Butterworths, London, p 201Google Scholar
  7. 7.
    Ionescu MI, Tandon AP, Mary DAS, Abid A (1977) Heart valve replacement with the Ionescu-Shiley pericardial xenograft. J Thorac Cardiovasc Surg 73:31PubMedGoogle Scholar
  8. 8.
    Johnson AD, Daily PO, Peterson KL, Le Winter M, Di Donna GJ, Blaire G, Niwayama G (1975) Functional evaluation of the porcine heterograft in the mitral position. Circulation [Suppl 1] 52:40Google Scholar
  9. 9.
    Jones EL, Craver JM, Morris DC, King SB III, Douglas JS Jr, Franck RH, Hatcher CR Jr, Morgan EA (1978) Hemodynamic and clinical evaluation of the Hancock xenograft bioprosthesis for aortic valve replacement (with emphasis on management of the small aortic root). J Thorac Cardiovasc Surg 75:300PubMedGoogle Scholar
  10. 10.
    Ott DA, Coelho AT, Cooley DA, Reul GJ Jr (1980) Ionescu-Shiley pericardial xenograft valve: Hemodynamic evaluation and early clinical follow-up of 326 patients. Cardiovasc Dis Bull Texas Heart Inst 7:137Google Scholar
  11. 11.
    Pietras RJ, Long DM, Rosen KM (1974) Late postoperative clinical and hemodynamic assessment of the early cloth-covered Starr-Edwards mitral valve prosthesis. J Thorac Cardiovasc Surg 67:450PubMedGoogle Scholar
  12. 12.
    Rodriguez L (1970) Haemodynamic and angiographic findings in patients with isolated aortic valvular disease before and after insertion of a Starr-Edwards ball-valve prosthesis. Scand J Thorac Cardiovasc Surg [Suppl 1] 5Google Scholar
  13. 13.
    Russell T II, Kremkau EL, Kloster P, Starr A (1972) Late haemodynamic function of cloth-covered Starr-Edwards valve prostheses. Circulation [Suppl 1] 45–46:8Google Scholar
  14. 14.
    Sigwart U, Schmidt H, Gleichmann U, Borst HG (1976) In vivo evaluation of the Lillehei-Kaster heart valve prosthesis. Ann Thorac Surg 22:213PubMedCrossRefGoogle Scholar
  15. 15.
    Tandon AP, Smith DR, Ionescu MI (1978) Hemodynamic evaluation of the Ionescu-Shiley pericardial xenograft in the mitral position. Am heart J 95:595PubMedCrossRefGoogle Scholar
  16. 16.
    Tandon AP, Smith DR, Whitaker W, Ionescu MI (1978) Long-term haemodynamic evaluation of the aortic pericardial xenograft. Br Heart J 40:602PubMedCrossRefGoogle Scholar
  17. 17.
    Walker DK, Scotten LN, Modi VJ, Brownlee RT (1980) In vitro assessment of mitral valve prostheses. J Thorac Cardiovasc Surg 79:680PubMedGoogle Scholar
  18. 18.
    Wright JTM (1979) Hydrodynamic evaluation of tissue valves. In: Ionescu MI (ed) Tissue heart valves. Butterworths, London, p 29Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • D. R. Smith
    • 1
  • A. P. Tandon
    • 1
  • S. S. Hassan
    • 1
  • M. I. Lonescu
    • 1
  1. 1.Departments of Cardiology and Cardiothoracic SurgeryRoyal Halifax Infirmary and Leeds General InfirmaryGreat Britain

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