Leriche Lecture On the Management of the Ichaemic Limb
When presented with a patient suffering from the effects of an obstructed artery, in the great majority of instances the cause is arteriosclerosis. We are presented therefore with a symptom of a generalised disease, and there is little we can do as regards the latter, but with modern techniques we can in most relieve the symptom, though often for only a relatively short time. It is interesting that in the more elderly, the results are very much better than in the younger patient (Tables 1 and 2). This suggests that in the younger group the disease process is more active. Royle of Melbourne (personal communication) showed that in dietary induced atheroma in rabbits, simple suture of the femoral artery led to atheromatous obstruction, as did simply passing a needle through the vessel wall. McManus (2) in his textbook of pathology noticed that in the 80-Year-old patient a previous atheromatous plaque was often represented by fibrous tissue. This seems to show that the disease becomes less active or tends to regress in the elderly.
KeywordsBete Rene Arteriosclerosis
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