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Influence of Cardiac Glycosides on Electrophysiologic Processes

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Part of the Handbook of Experimental Pharmacology book series (HEP,volume 56 / 1)

Abstract

An understanding of the effects of cardiac glycosides has been impaired mainly by the limited knowledge of the structures and functions upon which they act. With the introduction of new approaches to investigation, such as the voltage clamp technique or ion-selective microelectrodes, considerable progress has been made over the last decade. It is the purpose of this chapter to review the advances made in this field. The scope of this article has had to be confined to certain aspects of the overall problem. Emphasis will be placed on the mechanical and electrical actions that cardiac glycosides exert on isolated but otherwise “normal” ventricular tissue. The reader is also referred to other review articles (Vassalle, 1977; Beeler, 1977; Ferrier, 1977a; Tsien et al., 1978 a, b).

Keywords

  • Cardiac Glycoside
  • Positive Inotropic Effect
  • Purkinje Fiber
  • Ventricular Muscle
  • Inotropic Action

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Weingart, R. (1981). Influence of Cardiac Glycosides on Electrophysiologic Processes. In: Greeff, K. (eds) Cardiac Glycosides. Handbook of Experimental Pharmacology, vol 56 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68163-9_12

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