Introduction Elucidating Mechanisms of Eukaryotic Genetic Expression by Studying Animal Viruses

  • Aaron J. Shatkin
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 93)


Eukaryotic genetic expression is carefully regulated. Normal cell growth and division, tissue differentiation, and organism development all depend on a strictly ordered progression of specific events. Perturbation of the control of these processes, for example by exposure to harmful chemicals or infection with viruses leads to aberrant forms of metabolism, often resulting in malignancies and cell death. One of the most challenging problems in biology is to define at the molecular level the mechanisms that govern gene function in higher organisms, including ultimately man. This goal serves to unify the diverse efforts of many investigators, whether studying the precise patterns of embryo genesis, the loss of control that occurs during neoplastic growth or the redirection of biosynthetic pathways in virus-infected cells.


Animal Virus Eukaryotic mRNA Protein Synthesis Initiation Cytoplasmic Polyhedrosis Virus Viral Code Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • Aaron J. Shatkin
    • 1
  1. 1.Roche Institute of Molecular BiologyNutleyUSA

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