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Enzyme Histochemical Demonstration of Certain Cell Populations in Synovium Using Plastic-Embedded Whole Rat Joints

  • Conference paper
Arthritis

Abstract

Recent results in experimental arthritis research point to the possible importance of blood-born cells in the pathogenesis of chronic polyarthritis. Westerhellweg and Mohr [27], in adjuvant arthritis of rats, and Mohr and Wessinghage [14], in cases of human chronic polyarthritis, observed neutrophil granulocytes in the immediate vicinity of pannus-mediated destruction of articular cartilage. Autoradiographic studies in experimental allergic arthritis of guinea pigs led Ricken et al. [20] to assume that part of the hyperplastic synovial lining cells are progeny of myelogenic monocytes. Both these cell types possess fairly characteristic enzyme markers. Neutrophils show a comparatively high activity of naphthol-AS-D-chloroacetate-esterase [23], while monocytes/macrophages, on the other hand, are characterized by a diffuse reaction product of α-naphthyl-butyrateesterase [1].

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Authors
  1. W. Hermanns
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  2. L. C. Schulz
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Editor information

Editors and Affiliations

  1. Abteilung Immunologie und Transfusionsmedizin, Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule Hannover, Karl-Wiechert-Allee 9, 3000, Hannover 61, Federal Republic of Germany

    Helmuth Deicher

  2. Institut für Pathologie der Tierärztlichen, Hochschule Hannover, Bischofsholer Damm 15, 3000, Hannover 1, Federal Republic of Germany

    Leo-Clemens Schulz

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© 1981 Springer-Verlag Berlin Heidelberg

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Hermanns, W., Schulz, L.C. (1981). Enzyme Histochemical Demonstration of Certain Cell Populations in Synovium Using Plastic-Embedded Whole Rat Joints. In: Deicher, H., Schulz, LC. (eds) Arthritis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68106-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-68106-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10781-1

  • Online ISBN: 978-3-642-68106-6

  • eBook Packages: Springer Book Archive

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