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Plasma Concentrations and Hemodynamic Effects of Percutaneously Administered Nitroglycerin and Isosorbide Dinitrate in Healthy Volunteers

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Nitrates III

Abstract

The growing importance of epicutaneously applicable nitrates in the treatment of angina pectoris and heart failure prompted us to carry out a study in healthy volunteers in whom we monitored the plasma concentrations and hemodynamic effects and assured the tolerability of nitroglycerin (NTG) and isosorbide dinitrate (ISDN) administered in the form of ointments.

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References

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Authors
  1. P. R. Imhof
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  2. B. Ott
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  3. A. Weiss
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  4. L.-C. Chu
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  5. L. F. Chasseaud
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Editor information

Editors and Affiliations

  1. Abteilung für Kardiologie, Med. Hochschule Hannover, Karl-Wiechert-Allee 9, D-3000, Hannover 61, Germany

    P. R. Lichtlen

  2. Zentralkrankenhaus „Links der Weser“, Senator-Weßling-Straße, D-2800, Bremen 61, Germany

    H.-J. Engel

  3. Pharma-Schwarz GmbH, D-4019, Monheim, Germany

    A. Schrey

  4. Dept. of Cardiology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, 90048, Los Angeles, Calif., USA

    H. J. C. Swan (Director) (Director)

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© 1981 Springer-Verlag Berlin Heidelberg

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Imhof, P.R., Ott, B., Weiss, A., Chu, LC., Chasseaud, L.F. (1981). Plasma Concentrations and Hemodynamic Effects of Percutaneously Administered Nitroglycerin and Isosorbide Dinitrate in Healthy Volunteers. In: Lichtlen, P.R., Engel, HJ., Schrey, A., Swan, H.J.C. (eds) Nitrates III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68085-4_10

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  • DOI: https://doi.org/10.1007/978-3-642-68085-4_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68087-8

  • Online ISBN: 978-3-642-68085-4

  • eBook Packages: Springer Book Archive

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