Genetics of Reovirus
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Genetic studies aimed at a better understanding of aspects of the structure and function of the genome of mammalian reoviruses were initiated in the late 1960s. These began with the isolation and characterization of temperature-sensitive mutants (Fields and Joklik 1969, Ikegami and Gomatos 1968). Much of the early research in this area, performed mainly before 1975, has been described in a recent, detailed review (Cross and Fields 1977).
KeywordsGenome Segment Viral Hemagglutinin dsRNA Segment Reovirus Type Mammalian Reovirus
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