Clinical Results: Kidney and Urogenital Tract
Differentiation of CK isoenzymes was performed by immunoinhibition and immunoprecipitation techniques (see Chap. 3.3). In the sera of patients with acute renal failure elevated creatine kinase activity can be detected, see Table 1. The rate of activity is significantly higher in patients with shock symptoms than in patients without shock symptoms. The CK-MB isoenzyme activity shows a similar pattern, never exceeding 4% of total CK activity. It can safely be deduced that the CK-MB isoenzyme stems for skeletal muscle, especially in cases with shock symptoms. CK-BB isoenzyme could not be detected in any case above the detection limit of our methodology.
KeywordsCreatine Kinase Prostatic Carcinoma Chronic Renal Insufficiency Creatine Kinase Isoenzyme Immunoprecipitation Technique
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