Abstract
Retinoids control proliferation and differentiation of keratinizing and non-keratinizing epithelia. But there are some confusing, seemingly contradictory results on their effects and their mode of action.
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References
Brysk MM, Gray RH, Bernstein IA (1977) Tonofilament protein from newborn rat epidermis. Isolation, localization, and biosynthesis of marker of epidermal differentiation. J Biol Chem 252: 2127–2133
Christophers E (1974) Growth stimulation of cultured post-embryonic epidermal cells by vitamin A acid. J Invest Dermatol 63: 450–455
Davison P, Liu S, Karasek M (1979) Limitations in the use of 3H-thymidine incorporation into DNA as an indicator of epidermal keratinocyte proliferation in vitro. Cell Tissue Kinet 12: 605614
DeLuca L, Yuspa SH (1974) Altered glycoprotein synthesis in mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res 86: 106–110
Green H (1977) Terminal differentiation of cultured human epidermal cells. Cell 11: 405–416
Kripke ML, Glassman HN (1980) Retinoic acid and photocarcinogenesis workshop. J Am Acad Dermatol 2: 439–442
Leyva A, Kelley WN (1974) Measurement of DNA in cultured human cells. Anal Biochem 62: 173–179
Liu S, Karasek MA (1978) Isolation and serial cultivation of rabbit skin epithelial cells. J Invest Dermatol 70: 288–293
Liu S, Eaton MJ, Karasek MA (1979) Growth characteristics of human epidermal keratinocytes from newborn foreskin in primary and serial cultures. In Vitro 15: 813–822
Mahrle G, Berger H (1978) Protective effect of aromatic retinoic acid analog on skin tumor. J Invest Derm 70: 235
Mahrle G, Meyer-Hamme S, Ippen H (1981) Systemic treatment of keratinizing disorders of the skin and the mucous membrane with aromatic retinoid (Ro 10-9359). Comparative study on 113 patients. Arch Dermatol, in press
Nemanic MK, Elias PM Influence of retinoids on membrane glycosylation in epidermis. J Invest Dermatol, in press
Pullmann H, Lennartz KJ, Steigleder GK (1975) Die Proliferationskinetik normaler Epidermis vor and nach äußerlicher Anwendung einer 1%igen Vitamin A-Säure-Lösung. Arch Dermatol Res 253: 71–76
Shapiro SS, Poon JP (1978) Effect of retinyl acetate on sulfated glycosaminoglycan biosynthesis in dermal and epidermal cells in vitro. Connect Tissue Res 6: 101–108
Sporn MB, Dunlop MN, Newton DL, Henderson WR (1976) Relationships between structure and activity of retinoids. Nature 263: 110–113
Stüttgen G, Ippen H, Mahrle G (1977) Oral vitamin A acid in treatment of dermatoses with pathologic keratinization. Int J Dermatol 16: 500–502
Tsambaos D, Mahrle G, Orfanos CE (1980) Epidermal changes induced by oral excess of aromatic retinoid in guinea pigs. Arch Dermatol Res 267: 141–152
Wilkinson DI (1978) Effect of vitamin A acid on the growth of keratinocytes in culture. Arch Dermatol Res 263: 75–81
Yuspa SH, Harris CC (1974) Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res 86: 95–105
Yuspa SH, Elgjo K, Morse MA, Friedrich JW (1977) Retinyl acetate modulation of cell growth kinetics and carcinogen-cellular interaction in mouse epidermal cell cultures. Chem Biol Interact 16: 251–264
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© 1981 Springer-Verlag
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Mahrle, G.O., Wilkinson, D.I., Farber, E.M. (1981). Effects of Retinoids on Keratinocytes in vitro. In: Orfanos, C.E., Braun-Falco, O., Farber, E.M., Grupper, C., Polano, M.K., Schuppli, R. (eds) Retinoids. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68023-6_19
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DOI: https://doi.org/10.1007/978-3-642-68023-6_19
Publisher Name: Springer, Berlin, Heidelberg
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