Retinoid-Stimulated Material in Psoriatic Epidermis During Ro 10-9359 Therapy
Cell surface molecules modulate the cell-to-cell interactions which may control cell proliferation. Psoriasis is a disease in which abnormal epidermal cell interactions may play a pertinent role (13). Retinoids, which are known to be effective in psoriasis therapy, exert profound effects on squamous epithelia in cell culture and in vivo as manifested by mucous metaplasia and alterations in cell proliferation (10). Whether these biological effects are the result of differences in cell interactions induced by retinoids is unknown.
KeywordsIntercellular Space Pustular Psoriasis Uninvolved Skin Psoriatic Epidermis Retinoid Therapy
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