Abstract
The study of the chromosome pattern (karyotype) of human leukemic cells is one of the most rapidly progressing areas of clinical research. As more patients are examined, we are now able to correlate the karyotype with the type of leukemia and with the patient’s response to therapy. Chromosome analysis of leukemic cells thus can provide information of both diagnostic and prognostic significance. The clinical usefulness is largely the result of new technical advances in staining procedures that allow us to identify each chromosome precisely with banding techniques.
This work was supported in part by The University of Chicago Cancer Research Foundation and by Grant Numbers CA-16910 and CA-19266 awarded by the National Cancer Institute, U.S. Dept. of Health, Education, and Welfare. The Franklin-McLean Memorial Research Institute was operated by The University of Chicago for The U.S. Department of Energy under Contract No. EY 76-C-02-0069
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Rowley, J.D. (1981). Chromosome Studies in Children and Adults with Leukemia. In: Neth, R., Gallo, R.C., Graf, T., Mannweiler, K., Winkler, K. (eds) Modern Trends in Human Leukemia IV. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 26. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67984-1_3
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DOI: https://doi.org/10.1007/978-3-642-67984-1_3
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