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Immunhistologische Befunde

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Dickdarm

Part of the book series: Handbuch der inneren Medizin ((INNEREN 3,volume 3 / 4))

Zusammenfassung

Verschiedene abnorme Immunphänomene werden bei Patienten mit Colitis ulcerosa beobachtet. So wird die Bedeutung eines veränderten Immunsystems für die Pathogenese dieser Erkrankung seit längerem diskutiert (Übersicht: KIRSNER 1970; KIRSNER u. SHORTER 1975; JEWELL u. HODGSON 1976; PERLMANN et al. 1976; GEBBERS u. OTTO 1977; KRAFT 1979). Allerdings sind die meisten diesbezüglichen Befunde an zirkulierenden Leukozyten und durch serologische und in vitro Untersuchungen erhoben worden. Abnorme systemische Immunreaktionen, ob humoral oder zellulär, reflektieren nicht unbedingt auch Veränderungen der Schleimhaut. Es muß deshalb die Frage bislang offen bleiben, ob es sich hierbei um pathogenetisch bedeutsame Befunde oder nur um Sekundärreaktionen (Epiphänomene) handelt (JEWELL u. HODGSON 1976; AUER 1979; KRAFT 1979; s. hierzu auch S. 361ff.).

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Literatur

  • Allison AC (1978) Lysosomes in pathology. In: Anthony PP, Woolf N (eds) Recent advances in histopathology. Churchill Livingstone, Edinburgh London New York, pp 69–89

    Google Scholar 

  • Allison AC, Davies P (1975) Increased biochemical and biological activities of mononuclear phagocytes exposed to various stimuli, with special reference to secretion of lysosomal enzymes. In: Furth R van (ed) Mononuclear phagocytes in immunity, infection and pathology. Blackwell, Oxford, p 463

    Google Scholar 

  • Asquith P (ed) (1979) Immunology of the gastrointestinal tract. Churchill Livingstone, Edinburgh London New York

    Google Scholar 

  • Auer O (1979) Immunreaktionen bei Magen-Darm-Krankheiten mit Autoimmunmarkern. In: Seifert G, Classen M (Hrsg) Ergebnisse der Gastroenterologie, Bd 14. Demeter, Gräfelfing, S 48–60

    Google Scholar 

  • Baklien K (1977) Immunopathology of the gut. A study of the immunoglobulin system of the human intestine. Universitetsforlagets trykningssentral, Oslo

    Google Scholar 

  • Baklien K, Brandtzaeg P (1974) Local immunity and ulcerative colitis. Lancet 2:411–412

    Article  PubMed  CAS  Google Scholar 

  • Ballard J, Shiner M (1974) Evidence of cytotoxicity in ulcerative colitis from immunofluorescent staining of rectal mucosa. Lancet 1:1014–1017

    Article  PubMed  CAS  Google Scholar 

  • Bazin H (1976) The secretory antibody system. In: Ferguson A, MacSween RNM (eds) Immunological aspects of the liver and gastrointestinal tract. University Park Press, Baltimore, pp 33–82

    Google Scholar 

  • Becker EL, Henson PM (1973) In vitro studies of immunologically induced secretion of mediators from cells and related phenomena. Adv Immunol 17:94–193

    Google Scholar 

  • Bessis M (1973) Living blood cells and their ultrastructure. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Bienenstock J (1979) The physiology of the local immune response. In: Asquith P (ed) Immunology of the gastrointestinal tract. Churchill Livingstone, Edinburgh London New York, pp 14–22

    Google Scholar 

  • Bienenstock J, McDermott M, Befus D, O’Neill M (1978) A common mucosal immunologic system involving the bronchus, breast and bowel. In: McGhee JR, Mestecky J, Babb JL (eds) Secretory immunity and infection. Plenum Press, New York, pp 53–66

    Google Scholar 

  • Bookman MA, Bull DM (1979) Characteristics of isolated intestinal mucosal lymphoid cells in inflammatory bowel disease. Gastroenterology 77:503–510

    PubMed  CAS  Google Scholar 

  • Brandes D, Anton E, Orbegoso CM (1969) Hashimoto′s thyreoiditis. Ultrastructure and histochemistry of the cellular infiltrate. Johns Hopkins Med J 124:211–223

    PubMed  CAS  Google Scholar 

  • Brandtzaeg P, Baklien K (1976) Immunohistochemical studies of the formation and epithelial transport of immunoglobulins in normal and diseased human intestinal mucosa. Scand J Gastroenterol [Suppl 36] 11:1–45

    Google Scholar 

  • Brandtzaeg P, Baklien K, Fausa O, Hoel PS (1974) Immunohistochemical characterization of local immunoglobulin formation in ulcerative colitis. Gastroenterology 66:1123–1136

    PubMed  CAS  Google Scholar 

  • Cardella CJ, Davies P, Allison AC (1974) Immune complexes induce selective release of lysosomal hydrolases from macrophages. Nature 247:46–48

    Article  PubMed  CAS  Google Scholar 

  • Cebra J J, Emmons R, Gearhart PJ, Robertson SM, Tseng J (1978) Cellular parameters of the IgA response. In: McGhee JR, Mestecky J, Babb JL (eds) Secretory immunity and infection. Plenum Press, New York, pp 19–34

    Google Scholar 

  • Ceralli F, Familiari G, Marinozzi G, Muccioli-Casadei D (1976) The glycocalyx of the epithelial cells of the colon, observed in normal and ulcerous colitic conditions. Experientia 32:1542–1543

    Article  PubMed  CAS  Google Scholar 

  • Ciba Foundation Symposium 46 (1977) Immunology of the gut. Elsevier/Excerpta Medica/North-Holland, Amsterdam Oxford New York

    Google Scholar 

  • Das KM, Erber WF, Rubinstein A (1977) Immunohistochemical changes in morphologically involved and uninvolved mucosa of patients with idiopathic proctitis. J Clin Invest 59:379–385

    Article  PubMed  CAS  Google Scholar 

  • Das KM, Dubin R, Nagai T (1978) Isolation and characterization of colonic tissue-bound antibodies from patients with idiopathic ulcerative colitis. Proc Natl Acad Sci USA 75:4528–4532

    Article  PubMed  CAS  Google Scholar 

  • Davies P, Allison AC (1976) Secretion of macrophage enzymes in relation pathogenesis of chronic inflammation. In: Nelson S (ed) Immunobiology of the macrophage Academic Press, New York, pp 428–463

    Google Scholar 

  • Doe WF, Booth CC, Brown DL (1973) Evidence for complement-binding immune complexes in adult coeliac disease, Crohn′s disease and ulcerative colitis. Lancet 1:402–403

    Article  PubMed  CAS  Google Scholar 

  • Engström JF, Arvanitakis C, Sagawa A, Abdou NI (1978) Secretory immunoglobulin deficiency in a family with inflammatory bowel disease. Gastroenterology 74:747–751

    PubMed  Google Scholar 

  • Feinstein PA, Kaplan SR, Thayer WR (1976) The alternative complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein. Gastroenterology 70:181–185

    PubMed  CAS  Google Scholar 

  • Ferguson A, MacSween RNM (1976) Immunological aspects of the liver and gastrointestinal tract. University Park Press, Baltimore

    Google Scholar 

  • Fiorilli M, Luzi G, Aiuti F (1975) Immunoglobulin production by the rectal mucosa in subjects with ulcerative colitis. Rendic Gastroenterol 7:1–14

    Google Scholar 

  • Gebbers JO, Otto HF (1976) Plasma cell alterations in ulcerative colitis. An electron microscopic study. Pathol Eur 11:271–279

    PubMed  CAS  Google Scholar 

  • Gebbers J-O, Otto HF (1977 a) Zur Immunpathogenese der Colitis ulcerosa. Dtsch Med Wochenschr 102:400–406

    Article  PubMed  CAS  Google Scholar 

  • Gebbers J-O, Otto HF (1977 b) Immunohistochemical and electronmicroscopic observations on the local immune response in ulcerative colitis. Virchows Arch [Pathol Anat] 374:271–273

    CAS  Google Scholar 

  • Gebbers J-O, Otto HF (1978) Evidence for local immune complexes in ulcerative colitis. Acta Gastronenterol Belg 41:329–350

    CAS  Google Scholar 

  • Gelzayd EA, Kraft SC, Fitch FW, Kirsner JB (1968) Distribution of immunoglobulins in human rectal mucosa. II. Ulcerative colitis and abnormal mucosal control subjects. Gastroenterology 54:341–347

    PubMed  CAS  Google Scholar 

  • Goetze O, Mueller-Eberhard HJ (1971) The C3 activator system: An alternate pathway of complement activation. J Exp Med 134:90s–108s

    CAS  Google Scholar 

  • Gomez JA, Russell SW, Trowbridge JO, Lee J (1977) Canine histiocytic ulcerative colitis. An ultrastructural study of the early mucosal lesion. Dig Dis 22:485–496

    Article  CAS  Google Scholar 

  • Gray A, Doniach I (1970) Ultrastructure of plasma cells containing Russell bodies in human stomach and thyroid. J Clin Pathol 23:608–612

    Article  PubMed  CAS  Google Scholar 

  • Haakenstad AO, Mannik M (1977) The biology of immune complexes. In: Talal N (ed) Autoimmunity. Genetic, immunologic, virologic and clinical aspects. Adademic Press, New York, pp 277–360

    Google Scholar 

  • Hellwege HH, Bläker F, Gebbers J-O (1976) Hypokomplementämische membranoproliferative Glomerulonephritis bei einem Kind mit Colitis ulcerosa. Monatsschr Kinderheilkd 124:706–711

    PubMed  CAS  Google Scholar 

  • Henson PM (1971) Interaction of cells with immune complexes, adherence, release of constituents and tissue injury. J Exp Med 134:114s

    PubMed  CAS  Google Scholar 

  • Henson PM (1972) Pathologic mechanisms in neutrophil-mediated injury. Am J Pathol 68:593–612

    PubMed  CAS  Google Scholar 

  • Henson PM (1976) Secretion of lysosomal enzymes induced by immune complexes and complement. In: Dingle JT, Dean RT (eds) Lysosomes in biology and pathology. North-Holland, Amsterdam, p 99

    Google Scholar 

  • Hodgson HJF, Potter BJ, Jewell DP (1976) Immune complexes in inflammatory bowel disease. Clin Sci Mol Med 51:1–8

    Google Scholar 

  • Hodgson HJF, Potter BJ, Jewell DP (1977 a) Immune complexes in ulcerative colitis and Crohn′s disease. Clin Exp Immunol 29:187–196

    PubMed  CAS  Google Scholar 

  • Hodgson HJF, Potter BJ, Jewell DP (1977 b) C3 metabolism in ulcerative colitis and Crohn′s disease. Clin Exp Immunol 28:490–495

    PubMed  CAS  Google Scholar 

  • Hodgson HJF, Potter BJ, Skinner J, Jewell DP (1978) Immune-complex mediated colitis in rabbits. Gut 19:225–232

    Article  PubMed  CAS  Google Scholar 

  • Jewell DP, MacLennan ICM (1973) Circulating immune complexes in inflammatory bowel disease. Clin Exp Immunol 14:219–226

    PubMed  CAS  Google Scholar 

  • Jewell DP, Hodgson HJF (1976) Autoimmune and inflammatory disease of the gastrointestinal tract. In: Ferguson A, MacSween RNM (eds) Immunological aspects of the liver and gastrointestinal tract. University Park Press, Baltimore, pp 203–250

    Google Scholar 

  • Kirsner JB (1970) Ulcerative colitis 1970 — recent developments. Scand J Gastroenterol 6:63–91

    CAS  Google Scholar 

  • Kirsner JB, Shorter RG (eds) (1975) Inflammatory bowel disease. Lea & Febiger, Philadelphia

    Google Scholar 

  • Klockars M, Reitamo S, Reitamo J J, Möller C (1977) Immunohistochemical identification of lysozyme in intestinal lesions in ulcerative colitis and Crohn′s disease. Gut 18:377–381

    Article  PubMed  CAS  Google Scholar 

  • Koffler D, Minkowitz S, Rothman W (1962) Immunocytochemical studies in ulcerative colitis and regional ileitis. Am J Pathol 41:733–745

    PubMed  CAS  Google Scholar 

  • Kraft SC (1979) Inflammatory bowel disease (ulcerative colitis and Crohn′s disease). In: Asquith P (ed) Immunology of the gastrointestinal tract. Churchill Livingstone, Edinburgh London New York, pp 95–128

    Google Scholar 

  • Lachman PJ, Nicol P (1973) Reaction mechanism of the alternate pathway of complement fixation. Lancet 1:465–467

    Article  Google Scholar 

  • Lough J, Shuster J (1975) Constipated plasma cells associated with monomeric macroglobulinaemia. Hum Pathol 6:251–255

    Article  PubMed  CAS  Google Scholar 

  • Machado I, Falchuk ZM (1978) Lamina propria lymphocytes: Differing responses to mitogenic stimulation between inflammatory bowel disease and other diseases. Gastroenterology 74:1059A

    Google Scholar 

  • Maldonado JE, Brown AL, Bayrd ED, Pease GL (1966) Ultra structure of the myeloma cell. Cancer 19:1613–1627

    Article  PubMed  CAS  Google Scholar 

  • McClelland DBL, Shearman DJC, Lai A Fat RFM, Furth R van (1976) In vitro synthesis of immunoglobulin, secretory component, complement and lysozyme by human gastrointestinal tissue. II. Pathological tissue. Clin Exp Immunol 23:20–27

    PubMed  CAS  Google Scholar 

  • McCluskey RT, Hall CL, Colvin RB (1978) Immune complex mediated diseases. Hum Pathol 9:71–84

    Article  PubMed  CAS  Google Scholar 

  • Monteiro E, Fossey J, Shiner M, Drasar BS, Allison AC (1971) Antibacterial antibodies in rectal and colonic mucosa in ulcerative colitis. Lancet 1:249–251

    Article  PubMed  CAS  Google Scholar 

  • Nielsen H, Binder V, Daugharty H, Svehag S-E (1978a) Circulating immune complexes in ulcerative colitis. I. Correlation to disease activity. Clin Exp Immunol 31:72–80

    PubMed  CAS  Google Scholar 

  • Nielsen H, Hyltoft Petersen P, Svehag S-E (1978 b) Circulating immune complexes in ulcerative colitis. II. Correlation with serum protein concentrations and complement conversion products. Clin Exp Immunol 31:81–91

    PubMed  CAS  Google Scholar 

  • Osserman EF (1978) Multiple myeloma and related plasma cell dyscrasias. In: Samter M (ed) Immunological diseases, vol I. Little, Brown & Co, New York, pp 499–529

    Google Scholar 

  • Otto HF, Gebbers J-O (1978) Immunhistologische Untersuchungen zur lokalen humoralen Immunreaktion bei unbehandelter Colitis ulcerosa. Inn Med 2:69–77

    Google Scholar 

  • Otto HF, Gebbers J-O, Müller-Wieland K (1975) Untersuchungen zur Ultrastructurpathologie der Colitis ulcerosa. Virchows Arch [Pathol Anat] 367:113–130

    CAS  Google Scholar 

  • Perlmann P, Hammarström S, Lagercrantz R, Campbell D (1967) Autoantibodies to colon in rats and human ulcerative colitis. Cross-reactivity with Escherichia coli 0:14 antigen. Proc Soc Exp Biol Med 125:975–980

    PubMed  CAS  Google Scholar 

  • Perlmann P, Lagercrantz R, Hammarström S (1976) Lower gastrointestinal system: ulcerative colitis and Crohn′s disease (regional enterocolitis). In: Miescher PA, Müller-Eberhard HJ (eds) Textbook of immunopathology, vol II. Grune & Stratton, New York San Francisco London, pp 755–774

    Google Scholar 

  • Porter RR (1977) Structure and activation of the early components of complement. Fed Proc 36:2191–2196

    PubMed  CAS  Google Scholar 

  • Potter BJ, Hodgson HJ, Jewell DP (1975) C3 metabolism in inflammatory bowel disease. Gut 16:833–836

    PubMed  Google Scholar 

  • Ruchti C, Luscieti P, Laissue J, Schaffner Th, Hess MW, Cottier H (1979) Funktionelle Morphologie des intestinalen Immunsystems. Z Gastroenterol Verh-Bd 14:16–24

    Google Scholar 

  • Ruddy S, Gigli I, Austen KF (1972) The complement system of man. N Engl J Med 287:489–495, 545–549, 592–596, 642–646

    Article  PubMed  CAS  Google Scholar 

  • Sainte-Marie G (1964) Study on plasmocytopoiesis. I. Description of plasmacytes and of their mitoses in the mediastinal lymph nodes often-week-old rats. Am J Anat 114:207–215

    Article  PubMed  CAS  Google Scholar 

  • Shnitka TK (1964) Current concepts of the pathogenesis and pathology of inflammatory lesions of the intestine. Can Med Assoc J 91:7–22

    PubMed  CAS  Google Scholar 

  • Skinner JM, Whitehead R (1974) The plasma cells in inflammatory diseases of the colon: a quantitative study. J Clin Pathol 27:643–646

    Article  PubMed  CAS  Google Scholar 

  • Soeltoft J, Binder V, Gudman-Höyer E (1973) Intestinal immunoglobulins in ulcerative colitis. Scand J Gastroenterol 8:293–300

    Google Scholar 

  • Strober W, Krakauer R, Klaeveman HL, Reynolds HY, Nelson DL (1976) Secretory component deficiency. A disorder of the IgA immune system. N Engl J Med 294:351–356

    Article  PubMed  CAS  Google Scholar 

  • Teisberg P, Gjone E (1975) Humoral immune system activity in inflammatory bowel disease. Scand J Gastroenterol 10:545–549

    PubMed  CAS  Google Scholar 

  • Weissmann G (1964a) The role of lysosomes in inflammation and disease. Annu Rev Med 18:97–112

    Article  Google Scholar 

  • Weissmann G (1964 b) Lysosomes, autoimmune phenomena and diseases of connective tissue. Lancet 2:1373–1375

    Article  PubMed  CAS  Google Scholar 

  • Weissmann G, Zurier RB, Hoffstein S (1972) Leukocytic proteases and the immunologic release of lysosomal enzymes. Am J Pathol 68:539–562

    PubMed  CAS  Google Scholar 

  • White RG (1954) Observations on the formation and nature of Russell bodies. Br J Exp Pathol 35:365–376

    PubMed  CAS  Google Scholar 

  • Wilkinson PC (1977) Non-specific cells: granulocytes, mononuclear phagocytes and mast cells. In: Holborow EJ, Reeves WG (eds) Immunology in medicine. Academic Press, London, pp 231–264

    Google Scholar 

  • Zeromski J, Perlmann P, Lagercrantz R, Hammarstrom S, Gustafsson BE (1970) Immunological studies in ulcerative colitis. VII. Anti-colon antibodies of different immunoglobulin classes. Clin Exp Immunol 7:469–475

    PubMed  CAS  Google Scholar 

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Authors
  1. J.-O. Gebbers
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  2. H. F. Otto
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Editor information

Editors and Affiliations

  1. Kinderklinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    F. Bläker

  2. Pharmakologisches Institut, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    W. Braun

  3. Radiologische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    E. Bücheler

  4. Zentrum Chirurgie, Abteilung Kinderchirurgie, Klinikum der Universität, Im Neuenheimer Feld 110, D-6900, Heidelberg, Deutschland

    R. Daum

  5. Chirurgische Universitätsklinik Amsterdam, Wilhelmina Gasthuis, NL-1054 EG, Amsterdam, The Netherlands

    R. J. A. M. van Dongen

  6. Radiologisches Institut, Stadtklinik, Balgerstr. 50, D-7570, Baden-Baden, Deutschland

    W. Erbe

  7. Abteilung für Allgemeine Chirurgie mit Poliklinik, Chirurgische Universitätsklinik, Hugstetter Straße 55, D-7800, Freiburg i. Br., Deutschland

    E. H. Farthmann

  8. Kantonsspital Luzern, Medizinische Klinik, Gastroenterologische Abteilung, der Universität Zürich, CH-6004, Luzern, Switzerland

    L. Filippini (Lehrbeauftragter) (Lehrbeauftragter)

  9. Innere Abteilung, Krankenhaus St. Josef, Bergstr. 6-12, D-5600, Wuppertal-Elberfeld, Deutschland

    F. H. Franken

  10. Zentrum Psychologische Medizin, Abteilung für Psychosomatik, Medizinische Hochschule Hannover, Karl-Wiechert-Allee 9, D-3000, Hannover 61, Deutschland

    H. Freyberger

  11. Pathologisches Institut, Kantonsspital Luzern, CH-6004, Luzern, Switzerland

    J.-O. Gebbers

  12. Division of Gastroenterology, The Scripps Clinic and Research Foundation, University of California, San Diego, La Jolla, CA, USA

    W. S. Haubrich M.D., F.A.C.P.

  13. Medizinische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    K. H. Hölze

  14. I. Medizinische Abteilung, Städtisches Krankenhaus Neuperlach, Oskar-Maria-Graf-Ring 51, D-8000, München 83, Deutschland

    W. Kühner

  15. Psychiatrische Klinik, ehemaliger Chefarzt der Klinik des Bernhard-Nocht-Instituts für Schiffs- und Tropenkrankheiten, Oderfelder Str. 6, D-2000, Hamburg 13, Deutschland

    W. Mohr

  16. Medizinische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    K. Müller-Wieland

  17. I. Medizinische Abteilung, Stadtisches Krankenhaus Neuperlach, Oskar-Maria-Graf-Ring 51, D-8600, München 83, Deutschland

    R. Ottenjann

  18. Medizinische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    H. F. Otto

  19. Physiologisches Institut, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    H. J. Roose

  20. Medizinische Klinik, Abteilung für Klinische Immunologic, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    E. Rumberger

  21. Medizinische Klinik, Abteilung für Klinische Immunologie, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    W.-H. Schmiegel

  22. Chirurgische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    H. W. Schreiber

  23. Chirurgische Universitätsklinik Amsterdam, Wilhelmina Gasthuis, NL-1054 EG, Amsterdam, The Netherlands

    E.-D. Schwilden

  24. Abteilung für Gefäßchirurgie, z.Z. Städtische Krankenanstalten, Hirschlandstr. 97, D-7300, Esslingen a. Neckar, Deutschland

    E.-D. Schwilden

  25. Chirurgische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    N. Soehendra

  26. Chirurgische Universitätsklinik und Poliklinik, Sigmund-Freud-Str. 25, D-5300, Bonn 1, Deutschland

    F. Stelzner

  27. Medizinische Klinik, Abteilung für Klinische Immunologic, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    H.-G. Thiele

  28. Klinik für Innere Medizin, Abteilung für Gastroenterologie, Der Universität von Amsterdam, Wilhelmina Gasthuis, NL-1054 EG, Amsterdam, The Netherlands

    G. N. Tijtgat

  29. Chirurgische Abteilung, Kreiskrankenhaus, D-6640, Merzig, Deutschland

    B. Täger

  30. I. Medizinische Abteilung, Stadtisches Krankenhaus Neuperlach, Oskar-Maria-Graf-Ring 51, D-8000, München 83, Deutschland

    J. Weingart

  31. Chirurgische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    R. Winkler

  32. Medizinische Klinik, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    Kurt Müller-Wieland

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Gebbers, JO., Otto, H.F. (1982). Immunhistologische Befunde. In: Bläker, F., et al. Dickdarm. Handbuch der inneren Medizin, vol 3 / 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67945-2_14

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  • DOI: https://doi.org/10.1007/978-3-642-67945-2_14

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