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Dickdarm pp 297–339Cite as

Pathomorphologie

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Part of the book series: Handbuch der inneren Medizin ((INNEREN 3,volume 3 / 4))

Zusammenfassung

Colitis ulcerosa und Colitis granulomatosa Crohn sind differentialdiagno-stischzufolge klinischer, radiologischer, endoskopischer und histologischer Kriterien in aller Regel gut gegeneinander abzugrenzen (MCGOVERN 1969; PRICE u. MORSON 1975; KIRSNER 1975, 1978; YARDLEY u. DONOWITZ 1977; SOMMERS 1978; OTTO u. GEBBERS 1978a, b; FAHRLäNDER et al. 1979). Dennoch faßt man derzeit ulzeröse und granulomatöse Kolitiden unter dem Oberbegriff der „chronisch-entzündlichen Darmkrankheiten“ zusammen (Übersicht: KIRSNER u. SHORTER 1975). Die Gründe dafür liegen in gewissen Gemeinsamkeiten: zwischen ulzerösen und granulomatösen Kolitiden bestehen genetische Korrelationen, beide treten in etwa gleichen Altersklassen auf, sie zeigen einen chronisch-rezidivierenden Verlauf (eine gewissermaßen „autonome Progredienz“) mit gleichen extra-intestinalen Begleiterkrankungen (Komplikationen), sie sprechen mehr oder weniger gut auf eine vergleichbare medikamentöse Therapie an (SCHACHTER u. KIRSNER 1975; KIRSNER 1978; FAHRLÄNDER 1977, 1979; FAHRLÄNDER et al. 1979). Zudem ist derzeit weder für die Colitis ulcerosa noch für den Morbus Crohn eine „ätiologische Definition“ möglich. In der französischen Literatur wird demzufolee von einer „entérocolite crvntoénétiaue“ gesprochen.

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Otto, H.F., Gebbers, JO. (1982). Pathomorphologie. In: Bläker, F., et al. Dickdarm. Handbuch der inneren Medizin, vol 3 / 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67945-2_13

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