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Brain Abscess and Meningitis pp 214–216Cite as

Enhanced Fibrinolytic Activity in Patients with Subarachnoid Hemorrhage

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Part of the book series: Advances in Neurosurgery ((NEURO,volume 9))

Abstract

The most common causes of subarachnoid hemorrhage (SAH) are ruptured intracranial aneurysms, arterio-venous malformation and cranio-cerebral trauma. However, the percentage of unattributable cases of SAH varies between 20% and 50% (4). On the other hand indicators of activated fibrinolysis such as high levels of fibrinogen degradation products (FDP) have been found in the cerebrospinal fluid (CSF) of patients with SAH and it has been suggested that enhanced fibrinolytic activity (EFA) may be one of the many possible causes of rebleeding (1, 2, 7).

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References

  1. Ettinger, M.G.: Coagulation abnormalities in subarachnoid hemorrhage. Stroke 1 139–142 (1970)

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  2. Filizzolo, F., D’Angelo, V., Collice, M. et al.: Fibrinolytic activity in blood and cerebrospinal fluid in subarachnoid hemorrhage from ruptured intracranial saccular aneurysm before and during EACA treatment. Eur. Neurol. 17, 43–47 (1978)

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  3. Gibbs, J.R., O’Gorman, P.: Fibrinolysis in subarachnoid hemorrhage. Post grad. med. J. 43, 779–784 (1967)

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  4. Heidrich, R.: Subarachnoid hemorrhage. In: Handbook of clinical neurology, Vol 12. Vinken, P.J., Bruyn, G.W. (eds.), pp. 68–204. Amsterdam: North Holland Publishing Company 1972

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  5. Ott, E., Lechner, H., Ladurner, G. et al.: Fibrin stabilizing factor deficiency in subarachnoid hemorrhage. In: Cerebral vascular disease. Meyer, J.S., Lechner, H., Reivich, M. (eds.), pp. 157–158. Amsterdam: Excerpta Medica 1977

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  6. Ott, E., Lechner, H., Ladurner, G., Bertha, G.: Fibrinolytic activity and subarachnoid hemorrhage. Neurol. Psychiat. 3, in press (1980)

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  7. Tovi, D., Nilsson, I.M., Thulin, C.A.: Fibrinolytic activity of the CSF after subarachnoid haemorrhage. Acta neurol. scand. 49, 1–9 (1973)

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Authors
  1. E. Ott
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  2. G. Bertha
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  3. G. Ladurner
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  4. K. Marguc
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  5. H. Lechner
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Editor information

Editors and Affiliations

  1. Neurochirurgische Klinik, Der Universität Erlangen-Nürnberg, Schwabachanlage 6, (Kopfklinikum), D-8520, Erlangen, Deutschland

    W. Schiefer  & M. Klinger  & 

  2. Universitätsklinikum Steglitz Neurochirurgische Klinik und Poliklinik, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Deutschland

    M. Brock

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© 1981 Springer-Verlag Berlin Heidelberg

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Ott, E., Bertha, G., Ladurner, G., Marguc, K., Lechner, H. (1981). Enhanced Fibrinolytic Activity in Patients with Subarachnoid Hemorrhage. In: Schiefer, W., Klinger, M., Brock, M. (eds) Brain Abscess and Meningitis. Advances in Neurosurgery, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67943-8_34

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  • DOI: https://doi.org/10.1007/978-3-642-67943-8_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10539-8

  • Online ISBN: 978-3-642-67943-8

  • eBook Packages: Springer Book Archive

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