Skip to main content
SpringerLink
Log in
Book cover

Brain Abscess and Meningitis pp 189–196Cite as

Early Operation of Ruptured Cerebral Aneurysms: The Role of Norepinephrine in Subarachnoid Hemorrhage and in Experimental Vasospasm

  • Conference paper

Part of the book series: Advances in Neurosurgery ((NEURO,volume 9))

Abstract

It is now widely accepted that subarachnoid blood following aneurysm rupture plays a major role in the development of vasospasm. Then, early surgery with extensive removal of subarachnoid blood may have an advantage for the prevention of vasospasm. However, exact mechanisms to explain vasospasm have not been determined and are believed to be multifactorial. We are reporting on one of those factors, the adrenergic activity, by measuring norepinephrine (NE) concentrations in cerebrospinal fluid (CSF) from patients submitted to early aneurysm surgery, as well as by examining the arterial response to NE in experimental vasospasm.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Benedict, C.R., Loach, A.B.: Sympathetic nervous system activity in patients with subarachnoid hemorrhage. Stroke 9, 237–244 (1978)

    Article  PubMed  CAS  Google Scholar 

  2. Cummins, B.H., Lothian, D.: Amine levels in the cerebrospinal fluid after subarachnoid hemorrhage. Brit. J. Surg. 60, 910 (1973)

    PubMed  CAS  Google Scholar 

  3. Edvinsson, L., Aubineau, P., Owman, C., Sercombe, R., Seylaz, J.: Sympathetic innervation of cerebral arteries: Prejunctional supersensitivity to norepinephrine after sympathectomy or cocaine treatment. Stroke 6, 525–530 (1975)

    Article  PubMed  CAS  Google Scholar 

  4. Fraser, R.A.R., Stein, B.M., Barrett, R.E., Pool, J.L.: Noradrenergic mediation of experimental cerebrovascular spasm. Stroke 1, 356–362 (1970)

    Article  PubMed  CAS  Google Scholar 

  5. Goldman, M.R., Rogers, E.L., Rogers, M.C.: Subarachnoid hemorrhage. Association with unusual electrocardiographic changes. J.A.M.A. 234, 957–958 (1975)

    Article  PubMed  CAS  Google Scholar 

  6. Hunt, W.E.: Grading of risk in intracranial aneurysms. In: Recent progress in neurological surgery. Sano, K., Ishii, S., Le Vay, D. (eds.), pp. 169–175. Amsterdam: Excerpta Medica 1974

    Google Scholar 

  7. Iwayama, T., Burness, J.B., Burnstock, G.: Dual adrenergic and cholinergic innervation of the cerebral arteries of the rat. Circ. Res. 26, 635–646 (1970)

    PubMed  CAS  Google Scholar 

  8. Kim, J., Duckies, S.P., Hieshima, G.B., Bevan, R.B., Bevan, J.A.: Prolonged cerebral vasospasm in experimental subarachnoid hemorrhage (SAH) - an arterial factor. The American Association of Neurological Surgeons. Scientific manuscripts of annual meeting, pp. 59–61. New Orleans, Louisiana 1978

    Google Scholar 

  9. Meyer, J.S., Stoica, E., Pascu, J., Shimazu, K., Hartmann, A.: Catecholamine concentrations in CSF and plasma of patients with cerebral infarction and hemorrhage. Brain 96, 277–288 (1973)

    Article  PubMed  CAS  Google Scholar 

  10. Mori, K.: Automated measurement of catecholamines in urine by high-speed liquid chromatography with fluorometric detection. Jap. J. Ind. Health 16, 41–44 (1978)

    Article  CAS  Google Scholar 

  11. Peerless, S.J., Yasargil, M.G.: Adrenergic innervation of the cerebral blood vessels in the rabbit. J. Neurosurg. 35, 148–154 (1971)

    Article  PubMed  CAS  Google Scholar 

  12. Peerless, S.J., Griffiths, J.G.: Plasma catecholamines following subarachnoid hemorrhage. In: Subarachnoid hemorrhage and cerebrovascular spasm. Smith, R.R., Robertson, J.T. (eds.), pp. 148–156. Springfield, Ill.: Thomas 1975

    Google Scholar 

  13. Peerless, S.J., Kendall, M.J.: The innervation of the cerebral blood vessels. In: Subarachnoid hemorrhage and cerebrovascular spasm. Smith, R.R., Robertson, J.T. (eds.), pp. -8–54. Springfield, Ill.: Thomas 1975

    Google Scholar 

  14. Saito, I., Ueda, Y., Sano, K.: Significance of vasospasm in the treatment of ruptured intracranial aneurysms. J. Neurosurg. 47, 412–429 (1977)

    Article  PubMed  CAS  Google Scholar 

  15. Saito, I., Shigeno, T., Aritake, K., Tanishima, T., Sano, K.: Vasospasm assessed by angiography and computerized tomography. J. Neurosurg. 51, 466–475 (1979)

    Article  PubMed  CAS  Google Scholar 

  16. Shigeno, T., Aritake, K., Saito, I., Sano, K.: Hydrocephalus following early operation on ruptured cerebral aneurysms: Significance of long-term monitoring of intracranial pressure. In: Intracranial pressure IV. Shulman, K., Marmarou, A., Miller, J.D., Becker, D.P., Hochwald, G.H., Brock, M. (eds.), pp. 235–240. Berlin, Heidelberg, New York: Springer 1980

    Chapter  Google Scholar 

  17. Svengaard, N.-Aa., Edvinsson, L., Owman, Ch., Sahlin, Ch.: Increased sensitivity of the basilar artery to norepinephrine and 5-hydroxytryptamine following experimental subarachnoid hemorrhage. Surg. Neurol. 8, 191–195 (1977)

    Google Scholar 

  18. Wahl, M., Kuschinsky, W., Bosse, O., Olesen, J., Lassen, N.A., Ingvar, D.H., Michaelis, J., Thurau, K.: Effect of 1-norepine- phrine on the diameter of pial arterioles and arteries in the cat. Circ. Res. 31, 248–256 (1972)

    PubMed  CAS  Google Scholar 

  19. Wei, E.P., Raper, A.J., Kontos, H.A., Patterson, J.L.: Determinants of response of pial arteries to norepinephrine and sympathetic nerve stimulation. Stroke 6, 654–658 (1975)

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. T. Shigeno
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. Mori
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. Saito
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Sano
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Brock
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Neurochirurgische Klinik, Der Universität Erlangen-Nürnberg, Schwabachanlage 6, (Kopfklinikum), D-8520, Erlangen, Deutschland

    W. Schiefer  & M. Klinger  & 

  2. Universitätsklinikum Steglitz Neurochirurgische Klinik und Poliklinik, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Deutschland

    M. Brock

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Shigeno, T., Mori, K., Saito, I., Sano, K., Brock, M. (1981). Early Operation of Ruptured Cerebral Aneurysms: The Role of Norepinephrine in Subarachnoid Hemorrhage and in Experimental Vasospasm. In: Schiefer, W., Klinger, M., Brock, M. (eds) Brain Abscess and Meningitis. Advances in Neurosurgery, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67943-8_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67943-8_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10539-8

  • Online ISBN: 978-3-642-67943-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation