In Vitro Sensitization of Rat Mast Cells by Human Serum IgE Tested by Histamine Release
A successful sensitization of rat mast cells (RMC) by human IgE (HuIgE) was first reported by Perelmutter and Khera . In later experiments, Perelmutter and his collaborators confirmed these results [2–4] and other investigators also published positive results [5–7]. Nevertheless, Plaut et al.  were not able to sensitize RMC with HuIgE. The problem has still not been unambiguously solved.
KeywordsHistamine Release Histamine Liberation Vitro Sensitization Successful Sensitization Echinococcus Antigen
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