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Toxicology and Side-Effects of Anxiolytics

  • Chapter
Psychotropic Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 55 / 2))

Abstract

Although we tend to regard anxiety as a product of twentieth century living, anxiety, stress, and tension in their various forms must have been with man throughout his entire history. Indeed, as early as about 380 B.C., a statement was made by Plato in The Republic associating anxiety with a disease state: “Man is always fancying that he is being made ill, and is in constant anxiety about the state of his body” (Jowett, 1952). William Heberden also associated anxiety with disease in his celebrated lecture on angina pectoris to the Royal College of Physicians of London in 1768 (Heberden, 1772). During the last 50 years, thousands of papers have appeared in medical and scientific journals and dozens, if not hundreds, of books and monographs have been published on the pervasive subject of anxiety. “Indeed, anxiety has become the cornerstone of both psychosomatic medicine and psychiatric theory and practice” (Lief, 1967).

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  1. L. R. Hines
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  1. Institut für Pharmakologie, Bayer AG, Aprather Weg 18a, D-5600, Wuppertal 1, Germany

    F. Hoffmeister

  2. Institut für Arzneimittel des Bundesgesundheitsamtes, Stauffenbergstraße 13, D-1000, Berlin 30, Germany

    G. Stille

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Hines, L.R. (1981). Toxicology and Side-Effects of Anxiolytics. In: Hoffmeister, F., Stille, G. (eds) Psychotropic Agents. Handbook of Experimental Pharmacology, vol 55 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67767-0_7

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