Advantages and Disadvantages of Proteinanabolica

Abstract

This is to be a short review about possibilities and problems concerning the attempts to optimize the enteral and parenteral nutrition of severely injured patients by aid of protein anabolics. In surgical, traumatic and infectious stress, body protein is broken down more rapidly than it is formed and results in exess nitrogen being excreted in the urine. The metabolic rate is increased in proportion to the severity of illness and its complications. With major surgery, particulary with major burns, the energy requirement increases up to 20 MJ daily. The normal values lie between 7 to 10 MJ. If it is impossible to supply sufficient food via the gastrointestinal tract there must be recourse to i.v. feeding. Yet, although excellent maintenance solutions are available, due to hypermetabolism the N-balance often remains in the negative range.