Skip to main content
SpringerLink
Log in

Cardiotoxicity of Drugs Detected on Chicken Embryos

  • Conference paper
Further Studies in the Assessment of Toxic Actions

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 4))

Abstract

Results of direct observation of the effects of 9 drugs with known cardiotoxic properties upon the embryonic chick heart after intraamniotic administration on days 4 and 3 respectively, revealed the possibility of rough detection of cardiotoxic properties of newly developed drugs using the rapid, simple and inexpensive technique on chicken embryos.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Jelínek, R., Peterka, M.: One hundred substances tested with CHEST. Presented at the 6th Conference of European Teratology Society, September 4–7, 1978. Budapest, Hungary

    Google Scholar 

  • Jelinek, R.: Embryotoxicity assay on morphogenetic systems. In: Evaluation of embryotoxicity, mutagenicity and cardiogenicity risks in new drugs. Benešová, O., Rychter, Z., Jelínek, R. (eds.), pp. 195–206. Praha: Universita Karlova 1979

    Google Scholar 

  • Marhan, O., Jelínek, R., Rychter, Z., Řežábek, K.: Seventeen drugs compared in embryotoxicity tests using pregnant animals and a morphogenetic system. In: Evaluation of embryotoxicity, mutagenicity and cardiogenicity risks in new drugs. Benešová, O., Rychter, Z., Jelínek, R. (eds.), pp. 219–227, Praha: Universita Karlova 1979

    Google Scholar 

  • Pickering, J. W.: Experiments on the hearts of mammalian and chick embryos, with special references to action of electric currents. J. of Physiol. 20, 165–222 (1896)

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Experimental Medicine ČSAV, Legerova 61, 120 00, Praha 2, Czechoslovakia

    M. Peterka & R. Jelínek

  2. Department of Physiology and Pharmacology, Medical Faculty of Hygiene U.K., Ke Karlovu 4, 120 00, Praha 2, Czechoslovakia

    O. Benešová

Authors
  1. M. Peterka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Jelínek
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. O. Benešová
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Pharmacology, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers

  2. Institut für Pharmakologie und Toxikologie, Friedrich-Schiller-Universität Jena, DDR-6900, Jena, GDR

    Wolfgang Klinger

Rights and permissions

Reprints and permissions

Copyright information

© 1980 Springer-Verlag

About this paper

Cite this paper

Peterka, M., Jelínek, R., Benešová, O. (1980). Cardiotoxicity of Drugs Detected on Chicken Embryos. In: Chambers, P.L., Klinger, W. (eds) Further Studies in the Assessment of Toxic Actions. Archives of Toxicology, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67729-8_94

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67729-8_94

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10191-8

  • Online ISBN: 978-3-642-67729-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation