The Fate of Propoxur in Rat
The dynamics of absorption, distribution, biotransformation, and excretion of propoxur in rat was studied. The animals were given single doses of propoxur: a) 5 mg/kg intravenously (i.V.), b) 5 mg/kg 14-C labelled compound (1.5 μCi) intravenously, c) 50 mg/kg orally. The concentrations of propoxur and its metabolite 2-isopropoxyphenol were determined in blood, liver, kidneys, brain and urine. Pharmacokinetic data concerning absorption, distribution and excretion were calculated.
Key wordsCarbamate insecticides Propoxur Metabolism Excretion Distribution
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- WHO/FAO. 1973 Evaluation of some pesticide residues in food, WHO Pesticide residue series No. 3 (1974)Google Scholar