Behaviour Teratology Tests
Alterations in postnatal development resulting from intrauterine exposure are best recognized by performing a number of behavioural tests for which the means for quantification should be a basic requirement. The authors have used a modification of the Wahlsten 18 test scale for assessment of the physical development and unconditioned reflex development, together with additional tests providing quantitative data for embryotoxicity evaluation.
For the progeny CNS function estimation in an open field procedure as modified by Butcher has proved to be of value. A water T maze has been used for the assessment of learning ability and memory capacity.
The results obtained with prenatal exposure to lead acetate, alcohol, styrene and the fungicide endodan were presented and discussed.