Surgical Results After Preoperative Radiotherapy of Tumors of the Head and Neck
The following goals were set for the preoperative irradiation: (1) reduction of the tumor volume or achievement of operability of large tumors, (2) prevention of lymphogenous or hematogenous spread. An increase in postoperative complications, such as suture insufficiency, fistula, and arterial bleeding are the disadvantages associated with the positive effects of preoperative irradiation. The dose as well as the localization of the irradiation play an important role in the advantages and the disadvantages. A study of the literature gives no clear answer to this question, since the results of many authors are contradictory. The necessary dose is given as between 3000 and 6000 rads, with a clear increase in the operation risks between 4000 and 6000 rads. This “grey” region between 4000 and 6000 rads needs further research, on the one hand by radiobiology, on the other hand by clinical trials.
- Campana L (1964) Die Vorbestrahlung mit schnellen Elektronen. In: Zuppinger A, Poretti G (eds) Symposium on high-energy electrons, Montreux 1964. Springer, Berlin Heidelberg New York, pp 402–406Google Scholar