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Probing the Cytokinin Receptor Site(s)

  • Conference paper
Plant Growth Substances 1979

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

Our present understanding of the nature of the molecules that promote cytokinin activity is based on the finding by Miller et al. (1–3) of the growth factor kinetin (1; 6-furfurylaminopurine) in old and heated samples of DNA. The first active analog, 6-benzylaminopurine (2) (4–6), was prepared within days and presaged the synthesis of large numbers of compounds that have helped to define the structure-activity relationships for such species with considerable precision [see, e.g., (7–12)]. Although kinetin is presumably an artifact formed by rearrangement of 2′-deoxyadenosine, structurally related species such as 6-(3-methyl-2-butenylamino)purine (3) were subsequently identified as the growth factors in certain plant pathogens (13–15) and have now been shown to occur more generally in plants at the purine (16–25) and purine ribonucleos(t)ide levels (26 – 28).

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of Virginia, Charlottesville, 22901, Virginia, USA

    S. M. Hecht

  2. Department of Biology, University of Virginia, Charlottesville, 22901, Virginia, USA

    S. M. Hecht

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  1. S. M. Hecht
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Editors and Affiliations

  1. Department of Botany, University of Wisconsin, 53706, Madison, Wisconsin, USA

    Folke Skoog

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© 1980 Springer-Verlag Berlin Heidelberg

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Hecht, S.M. (1980). Probing the Cytokinin Receptor Site(s). In: Skoog, F. (eds) Plant Growth Substances 1979. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67720-5_14

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  • DOI: https://doi.org/10.1007/978-3-642-67720-5_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67722-9

  • Online ISBN: 978-3-642-67720-5

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