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Paraneoplastische endokrine Syndrome

  • Ph. U. Heitz
  • J.-J. Staub
Part of the Spezielle pathologische Anatomie book series (SPEZIELLE, volume 14)

Zusammenfassung

Die Erkennung klinischer Syndrome, welche auf die Sekretion von Hormonen durch „nicht endokrine“Tumoren zurückgeführt werden können, gehört zu den markantesten, während der letzten Jahre erzielten Fortschritten der Endokrinologie. Es ist heute bekannt, daß metabolische Auswirkungen derartiger Tumoren gefährlicher sein können als das Tumorwachstum selbst. Andererseits können Messungen von Hormonen als „Marker“für bestimmte Tumoren Hinweise auf den Sitz des Primärtumors geben und das Fortschreiten der Erkrankung bzw. den Erfolg der Therapie anzeigen. Diese Erkenntnisse haben zur Entstehung eines neuen interdisziplinären Arbeitsfeldes zwischen Endokrinologie und Onkologie geführt. Die Analyse dieser Phänomene ermöglicht es, Rückschlüsse auf ontogenetische Zusammenhänge und die Differenzierung verschiedener Gewebe zu ziehen. Sie erlaubt zudem fundamentale Einblicke in die Tumorbiologie und deren Regulationsmechanismen.

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© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • Ph. U. Heitz
    • 1
  • J.-J. Staub
    • 1
  1. 1.BaselSchweiz

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