Abstract
High resolution electron microscopic structure analysis of biomacromolecules is chiefly limited by two factors: specimen preservation/damage in vacuo, and radiation. Progress had been made in both of these areas, as attested to by the elegant structure determination of the purple membrane by Unwin and Henderson [14,8]. Specimen preservation in vacuo was accomplished, in that case, by glucose embedment. The radiation damage problem was overcome to a certain extent by the use of Fourier methods, which allowed the averaging of many unit cells.
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© 1980 Springer-Verlag Berlin Heidelberg
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Hayward, S.B., Glaeser, R.M. (1980). Use of Low Temperatures for Electron Diffraction and Imaging of Biological Macromolecular Arrays. In: Baumeister, W., Vogell, W. (eds) Electron Microscopy at Molecular Dimensions. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67688-8_26
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DOI: https://doi.org/10.1007/978-3-642-67688-8_26
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