Abstract
Regular two-dimensional arrays of proteins are quite common in Nature. Some examples that are discussed in this volume are: (i) surface layers on bacterial cell walls (contribution U.B. Sleytr); (ii) microtubules (contribution E. Mandelkow et al.), and (iii) virus shells (this contribution). Assembly of these structures is generally controlled in time and space, i.e., shape, size, and for example for microtubules the direction of assembly, are regulated. The information for specifying these parameters is often only to a limited extent stored in the structural protein that forms the two-dimensional lattice. In many cases other proteins are involved as well.
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References
Arisaka F, Tschopp J, Driel van R, Engel J (1980) Reassembly of the bacteriophage T4 tail from the core baseplate and the monomeric sheath protein P18. A cooperative process. J Mol Biol in press
Bijlenga RKL, Broek van den R, Kellenberger E (1974) The transformation of tau-particles into T4 heads. I. Evidence for the conservative mode of this transformation. J Supramol Struct 2: 45–59
Black LW (1974) Bacteriophage T4 internal protein mutants. Virology 60: 166–179
Branton D, Klug A (1975) Capsid geometry of baeteriophage T2: a freeze etching study. J Mol Biol 92: 559–565
Casjens S, King J (1975) Virus assembly. Annu Rev Biochem 44: 555–611
Driel van R (1977) Assembly of bacteriophage T4 head-related structures. Assembly of polyheads in vitro J Mol Biol 114: 61–78
Driel van R, (in press, 1980) Assembly of baeteriophage T4 head-related struetures IV. Isolation and association properties of T4 prehead proteins. J Mol Biol in press
Driel van R, Couture E (1978a) Assembly of baeteriophage T4 head-related struetures II. In vitro assembly of prehead-like structures. J Mol Biol 123: 115–128
Driel van R, Couture E (1978b) Assembly of the scaffolding core of baeteriophage T4 preheads. J Mol Biol 123: 713–719
Kurtz MB, Champe SP (1977) Precursors of the T4 internal peptides. J Virol 22: 412–419
Laemmli UK, Quittner SF (1974) Maturation of the head of baeteriophage T4. The proteins of the core of tubular polyheads and in vitro cleavage of the head proteins. Virology 62: 483–499
Laemmli UK, Mölbert E, Showe MK, Kellenberger E (1970) Form determining function of the genes required for the assembly of the head of baeteriophage T4. J Mol Biol 49: 99–113
Müller-Salamin L, Onorato L, Showe MK (1977) Localization of minor protein components of the head of baeteriophage T4. J Virol 24: 121–134
Onorato L, Stirmer B, Showe MK (1978) Isolation and characterization of baeteriophage T4 mutant preheads. J Virol 27: 409–426
Paulson JR, Laemmli UK (1977) Morphogenetic core of baeteriophage T4 head. Structure of the core in polyheads. J Mol Biol 111: 459–485
Showe MK, Onorato L (1978) Kinetic factors and form determination of the head of baeteriophage T4. Proc Natl Acad Sci USA 75: 4165–4169
Simon LD (1972) Infection of Escherichia coli by T2 and T4 bacteriophages as seen in the electron microscope: T4 head morphogenesis. Proc Natl Acad Sci USA 69: 907–911
Spiegelman BM, Lopata MA, Kirschner MW (1979a) Multiple sites for the initiation of microtubule assembly in mammalian cells. Cell 16: 239–252
Spiegelman, BM, Lopata MA, Kirschner MW (1979b) Aggregation of microtubule initiation sites preceding neurite outgrowth in mouse neuroblastoma cells. Cell 16: 253–263
Steven AC, Aebi U, Showe MK (1976a) Folding and capsomere morphology of the P23 surface shell of bacteriophage T4 polyheads from mutants in five different head genes. J Mol Biol 102: 373–407
Steven AC, Couture E, Aebi U, Showe MK (1976b) Structure of T4 polyheads II. A pathway of polyhead transformation as a model for capsid maturation. J Mol Biol 106: 187–221
Tschopp J, Arisaka F, Van Driel R, Engel J (1979) Purification, characterization and reassembly of the bacteriophage T4D tail sheath protein P18. J Mol Biol 128: 247–258
Wunderli H, Broek van den J, Kellenberger E (1977) Studies related to the head-maturation pathway of bacteriophage T4 and T2:1. Morphology and kinetics of intracellular particles produces by mutants in the maturation genes. J Supramol Struct 7: 135–161
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van Driel, R. (1980). The Role of a Scaffolding Core in the Assembly of the Bacteriophage T4 Head Shell Lattice. In: Baumeister, W., Vogell, W. (eds) Electron Microscopy at Molecular Dimensions. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67688-8_15
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